Study of Three-Component Reactions Between 5-Amino-3-Methylisoxazole, N-Arylamides of Acetoacetic Acid, and Aromatic Aldehydes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-11

AUTHORS

V. V. Tkachenko, E. A. Muravyova, S. V. Shishkina, O. V. Shishkin, S. M. Desenko, V. A. Chebanov

ABSTRACT

A three-component cyclocondensation between 5-amino-3-methylisoxazole, N-arylamides of aceto-acetic acid, and aromatic aldehydes was studied under the conditions of thermal activation and ultrasonication. Upon heating in n-butanol, depending on the substituent in aldehyde, the reaction produced either N,4-diaryl-3,6-dimethylisoxazolо[5,4-b]pyridine-5-carboxamides, or their 4,7-dihydro derivatives. Ultrasonication unexpectedly produced N1,N3,2-triaryl-4-hydroxy-4-methyl-6-oxocyclo-hexane-1,3-dicarboxamides.

PAGES

1166-1176

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10593-014-1578-0

DOI

http://dx.doi.org/10.1007/s10593-014-1578-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044170643


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