Synthesis of 5-Trifluoroacetylpyrrole-2-Carbaldehydes* View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-09-12

AUTHORS

O. V. Petrova, M. V. Markova, I. A. Ushakov, L. N. Sobenina, E. V. Tretyakov, V. I. Ovcharenko, A. I. Mikhaleva, B. A. Trofimov

ABSTRACT

5-Trifluoroacetylpyrrole-2-carbaldehydes were synthesized by low-temperature trifluoroacetylation of pyrrole-2-carbaldehyde acetals using trifluoroacetic anhydride, with subsequent removal of the acetal protecting group by mild acid-catalysed hydrolysis. The hydrolysis was accompanied by the formation of a minor product, (1Е,4Е)-1,5-bis[5-(2,2,2-trifluoroacetyl)-1Н-pyrrol-2-yl]-1,4-pentadien-3-one, which was isolated and identified.

PAGES

941-945

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10593-014-1548-6

DOI

http://dx.doi.org/10.1007/s10593-014-1548-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042139095


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