Synthesis and some properties of 5-alkylamino-2-(phthalimidoalkyl)-1,3-oxazole-4-carbonitriles View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-11-24

AUTHORS

S. A. Chumachenko, O. V. Shablykin, A. N. Vasilenko, V. S. Brovarets

ABSTRACT

5-Alkylamino-1,3-oxazole-4-carbonitriles containing a 2-phthalimidoethyl or 3-phthalimidopropyl substituent at position 2 of the oxazole ring were synthesized. In the reaction of 5-(morpholin-4-yl)-2-(2-phthalimidoethy)l-1,3-oxazole-4-carbonitrile with hydrazine hydrate, 2-(2-aminoethyl)-5-(morpholin-4-yl)-1,3-oxazole-4-carbonitrile is formed. In the case of the 3-phthalimidopropyl analog, the recyclization product 3-amino-2-(morpholin-4-ylcarbonyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole is formed.

PAGES

1020-1028

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10593-011-0869-y

DOI

http://dx.doi.org/10.1007/s10593-011-0869-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020184622


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