Refinement of macaque synteny arrangement with respect to the official rheMac2 macaque sequence assembly View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-10-10

AUTHORS

Roberta Roberto, Doriana Misceo, Pietro D’Addabbo, Nicoletta Archidiacono, Mariano Rocchi

ABSTRACT

We have compared the synteny block organization of the official macaque genome sequence assembly (Jan. 2006; rheMac2) with an independent assembly that used a molecular cytogenetic approach. The mapping of four synteny segments, ranging in size from 4 Mb to 24 Mb, was found to be inconsistent between the two datasets. We specifically investigated these discrepancies by appropriate co-hybridization FISH experiments with validated reference probes located outside the area under study. We found that in the macaque rheMac2 release three synteny segments were wrongly mapped and one segment was incorrectly oriented. More... »

PAGES

977-985

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10577-008-1255-1

DOI

http://dx.doi.org/10.1007/s10577-008-1255-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015745547

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18841486


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