Long bone mesenchymal stem cells (Lb-MSCs): clinically reliable cells for osteo-diseases View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-08-16

AUTHORS

Shirin Toosi, Hojjat Naderi-Meshkin, Fatemeh Kalalinia, Mohammad Taghi Pievandi, Hossein Hosseinkhani, Ahmad Reza Bahrami, Asieh Heirani-Tabasi, Mahdi Mirahmadi, Javad Behravan

ABSTRACT

Mesenchymal stem cells (MSCs) have been designated as the most reliable cells in clinics to treat osteo-diseases because of their versatile nature. MSCs, isolated from long bone (Lb-MSCs) are rarely reported and named as RIA-MSCs because of the reamer–irrigator–aspirator (RIA) device. The potential of these cells in the treatment of non-union bone fractures made them the ideal candidates to be studied for clinical practices. In this work, effect of cryopreservation on the proliferation and differentiation capabilities of long bone MSCs (Lb-MSCs) has been studied. For this purpose, Lb-MSCs were isolated via RIA device and characterized using flow cytometry and differentiation assays. Cells were cryopreserved for 3, 6 and 12 months and thereafter were characterized using differentiation assays and genetic markers specific for osteogenic, chondrogenic, and adipogenic potential quantitatively by qRT-PCR. Lb-MSCs were found expressing MSC characteristic markers defining their identity. The population doubling time (PDT) was about 2.5 ± 0.5 days and colonies appeared after 7–10 days. Differentiation potential and gene expression of 3, 6 and 12 months cryopreserved Lb-MSCs were unaltered. The results show that cryopreservation did not have an effect on the differentiation potential of human Lb-MSCs. Therefore, our work offers Lb-MSCs as clinically cells for treating osteo-diseases. More... »

PAGES

489-500

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10561-017-9652-3

DOI

http://dx.doi.org/10.1007/s10561-017-9652-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091220758

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28815364


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone and Bones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Culture Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Differentiation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Proliferation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chondrogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cryopreservation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diastasis, Bone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mesenchymal Stem Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Osteogenesis", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411583.a", 
          "name": [
            "Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Toosi", 
        "givenName": "Shirin", 
        "id": "sg:person.014212754751.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014212754751.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Naderi-Meshkin", 
        "givenName": "Hojjat", 
        "id": "sg:person.0715547640.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0715547640.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical Genetic Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411583.a", 
          "name": [
            "Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran", 
            "Medical Genetic Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kalalinia", 
        "givenName": "Fatemeh", 
        "id": "sg:person.01354672317.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354672317.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopedic Surgery, Orthopedic and Trauma Research Center, Mashhad University of Medical Sciences, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411583.a", 
          "name": [
            "Department of Orthopedic Surgery, Orthopedic and Trauma Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pievandi", 
        "givenName": "Mohammad Taghi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan", 
          "id": "http://www.grid.ac/institutes/grid.260770.4", 
          "name": [
            "School of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hosseinkhani", 
        "givenName": "Hossein", 
        "id": "sg:person.0773173167.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773173167.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bahrami", 
        "givenName": "Ahmad Reza", 
        "id": "sg:person.0673027625.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673027625.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heirani-Tabasi", 
        "givenName": "Asieh", 
        "id": "sg:person.01335211077.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335211077.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mirahmadi", 
        "givenName": "Mahdi", 
        "id": "sg:person.0722061436.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722061436.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad, Iran", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran", 
            "Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Behravan", 
        "givenName": "Javad", 
        "id": "sg:person.01245756105.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245756105.18"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.gt.3301760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034195992", 
          "https://doi.org/10.1038/sj.gt.3301760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00316069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039888162", 
          "https://doi.org/10.1007/bf00316069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10517-006-0214-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001751346", 
          "https://doi.org/10.1007/s10517-006-0214-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00264-004-0547-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033915925", 
          "https://doi.org/10.1007/s00264-004-0547-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/6529", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040720175", 
          "https://doi.org/10.1038/6529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00264-011-1338-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030535452", 
          "https://doi.org/10.1007/s00264-011-1338-z"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-08-16", 
    "datePublishedReg": "2017-08-16", 
    "description": "Mesenchymal stem cells (MSCs) have been designated as the most reliable cells in clinics to treat osteo-diseases because of their versatile nature. MSCs, isolated from long bone (Lb-MSCs) are rarely reported and named as RIA-MSCs because of the reamer\u2013irrigator\u2013aspirator (RIA) device. The potential of these cells in the treatment of non-union bone fractures made them the ideal candidates to be studied for clinical practices. In this work, effect of cryopreservation on the proliferation and differentiation capabilities of long bone MSCs (Lb-MSCs) has been studied. For this purpose, Lb-MSCs were isolated via RIA device and characterized using flow cytometry and differentiation assays. Cells were cryopreserved for 3, 6 and 12\u00a0months and thereafter were characterized using differentiation assays and genetic markers specific for osteogenic, chondrogenic, and adipogenic potential quantitatively by qRT-PCR. Lb-MSCs were found expressing MSC characteristic markers defining their identity. The population doubling time (PDT) was about 2.5\u00a0\u00b1\u00a00.5\u00a0days and colonies appeared after 7\u201310\u00a0days. Differentiation potential and gene expression of 3, 6 and 12\u00a0months cryopreserved Lb-MSCs were unaltered. The results show that cryopreservation did not have an effect on the differentiation potential of human Lb-MSCs. Therefore, our work offers Lb-MSCs as clinically cells for treating osteo-diseases.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s10561-017-9652-3", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1023785", 
        "issn": [
          "1389-9333", 
          "1573-6814"
        ], 
        "name": "Cell and Tissue Banking", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "keywords": [
      "mesenchymal stem cells", 
      "differentiation potential", 
      "differentiation assays", 
      "stem cells", 
      "bone mesenchymal stem cells", 
      "non-union bone fractures", 
      "qRT-PCR", 
      "gene expression", 
      "genetic markers", 
      "RIA-MSCs", 
      "differentiation capability", 
      "cells", 
      "characteristic markers", 
      "effect of cryopreservation", 
      "flow cytometry", 
      "assays", 
      "chondrogenic", 
      "versatile nature", 
      "markers", 
      "reliable cell", 
      "colonies", 
      "expression", 
      "proliferation", 
      "cryopreservation", 
      "potential", 
      "RIA device", 
      "cytometry", 
      "identity", 
      "population", 
      "long bones", 
      "ideal candidate", 
      "effect", 
      "candidates", 
      "days", 
      "bone fractures", 
      "clinical practice", 
      "aspirator device", 
      "bone", 
      "results", 
      "nature", 
      "work", 
      "treatment", 
      "months", 
      "time", 
      "clinic", 
      "capability", 
      "fractures", 
      "practice", 
      "purpose", 
      "devices", 
      "long bone MSCs", 
      "Lb-MSCs", 
      "MSC characteristic markers", 
      "human Lb-MSCs"
    ], 
    "name": "Long bone mesenchymal stem cells (Lb-MSCs): clinically reliable cells for osteo-diseases", 
    "pagination": "489-500", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1091220758"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10561-017-9652-3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28815364"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10561-017-9652-3", 
      "https://app.dimensions.ai/details/publication/pub.1091220758"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:38", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_719.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s10561-017-9652-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9652-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9652-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9652-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9652-3'


 

This table displays all metadata directly associated to this object as RDF triples.

256 TRIPLES      22 PREDICATES      98 URIs      83 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10561-017-9652-3 schema:about N1387efaf2c7042809def5d3d262acacb
2 N2d0ba36b8b8c4f969c34f3b8ea9775b4
3 N5a4cd611f26147d5a5697d6066349911
4 N6bb6048501f0434fa7425d882bb2e874
5 N74c3abbde5164b5c911347638f457318
6 N8c0330b37657439a8fa39a07d243347a
7 Nc53604009cd243c69ec2a4beb102c54f
8 Ndb8e0a0ec98b4e09bd0fb66f62d06197
9 Ne2df8d85d32b4069a323d44667a53428
10 Ne70c79f1e9264e76847be688b1639862
11 Nfae397edb1aa4459aa3e519ef226d1b0
12 anzsrc-for:11
13 anzsrc-for:1103
14 anzsrc-for:1109
15 schema:author N65e845fcf0f24bc294e57499768229e8
16 schema:citation sg:pub.10.1007/bf00316069
17 sg:pub.10.1007/s00264-004-0547-0
18 sg:pub.10.1007/s00264-011-1338-z
19 sg:pub.10.1007/s10517-006-0214-0
20 sg:pub.10.1038/6529
21 sg:pub.10.1038/sj.gt.3301760
22 schema:datePublished 2017-08-16
23 schema:datePublishedReg 2017-08-16
24 schema:description Mesenchymal stem cells (MSCs) have been designated as the most reliable cells in clinics to treat osteo-diseases because of their versatile nature. MSCs, isolated from long bone (Lb-MSCs) are rarely reported and named as RIA-MSCs because of the reamer–irrigator–aspirator (RIA) device. The potential of these cells in the treatment of non-union bone fractures made them the ideal candidates to be studied for clinical practices. In this work, effect of cryopreservation on the proliferation and differentiation capabilities of long bone MSCs (Lb-MSCs) has been studied. For this purpose, Lb-MSCs were isolated via RIA device and characterized using flow cytometry and differentiation assays. Cells were cryopreserved for 3, 6 and 12 months and thereafter were characterized using differentiation assays and genetic markers specific for osteogenic, chondrogenic, and adipogenic potential quantitatively by qRT-PCR. Lb-MSCs were found expressing MSC characteristic markers defining their identity. The population doubling time (PDT) was about 2.5 ± 0.5 days and colonies appeared after 7–10 days. Differentiation potential and gene expression of 3, 6 and 12 months cryopreserved Lb-MSCs were unaltered. The results show that cryopreservation did not have an effect on the differentiation potential of human Lb-MSCs. Therefore, our work offers Lb-MSCs as clinically cells for treating osteo-diseases.
25 schema:genre article
26 schema:inLanguage en
27 schema:isAccessibleForFree false
28 schema:isPartOf N29ce73bb25d64bd6b50cfc0761023b75
29 Nb58801c8973443e7ba7fe5812e66671d
30 sg:journal.1023785
31 schema:keywords Lb-MSCs
32 MSC characteristic markers
33 RIA device
34 RIA-MSCs
35 aspirator device
36 assays
37 bone
38 bone fractures
39 bone mesenchymal stem cells
40 candidates
41 capability
42 cells
43 characteristic markers
44 chondrogenic
45 clinic
46 clinical practice
47 colonies
48 cryopreservation
49 cytometry
50 days
51 devices
52 differentiation assays
53 differentiation capability
54 differentiation potential
55 effect
56 effect of cryopreservation
57 expression
58 flow cytometry
59 fractures
60 gene expression
61 genetic markers
62 human Lb-MSCs
63 ideal candidate
64 identity
65 long bone MSCs
66 long bones
67 markers
68 mesenchymal stem cells
69 months
70 nature
71 non-union bone fractures
72 population
73 potential
74 practice
75 proliferation
76 purpose
77 qRT-PCR
78 reliable cell
79 results
80 stem cells
81 time
82 treatment
83 versatile nature
84 work
85 schema:name Long bone mesenchymal stem cells (Lb-MSCs): clinically reliable cells for osteo-diseases
86 schema:pagination 489-500
87 schema:productId N8e074af214624df9aa07fd9279f4bdcd
88 Na1fa0e424aa44ce29e57e55249869f73
89 Nda1bb98e6ddd4e10bab16f2f05934b25
90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091220758
91 https://doi.org/10.1007/s10561-017-9652-3
92 schema:sdDatePublished 2021-12-01T19:38
93 schema:sdLicense https://scigraph.springernature.com/explorer/license/
94 schema:sdPublisher N39d9cd59842545d79f0d26ee51f34363
95 schema:url https://doi.org/10.1007/s10561-017-9652-3
96 sgo:license sg:explorer/license/
97 sgo:sdDataset articles
98 rdf:type schema:ScholarlyArticle
99 N113a7f0074c2447aa73573943f0f4dbc schema:affiliation grid-institutes:grid.411583.a
100 schema:familyName Pievandi
101 schema:givenName Mohammad Taghi
102 rdf:type schema:Person
103 N12f607071726436aba0eb8fd45a36912 rdf:first sg:person.0673027625.55
104 rdf:rest N315342c2b6e049ce80bf196f336bb1ea
105 N1387efaf2c7042809def5d3d262acacb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Cell Differentiation
107 rdf:type schema:DefinedTerm
108 N24b3b14b0efd4350bc1cb76af49a58b9 rdf:first sg:person.0715547640.10
109 rdf:rest Ne444ef76085641e2b0bf43b1525be07b
110 N27a0831dda6549d2bcba8b822ecc2fd5 rdf:first N113a7f0074c2447aa73573943f0f4dbc
111 rdf:rest Nbc982ecc972e4b89b7af7025a907ec75
112 N29ce73bb25d64bd6b50cfc0761023b75 schema:volumeNumber 18
113 rdf:type schema:PublicationVolume
114 N2d0ba36b8b8c4f969c34f3b8ea9775b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Cells, Cultured
116 rdf:type schema:DefinedTerm
117 N315342c2b6e049ce80bf196f336bb1ea rdf:first sg:person.01335211077.35
118 rdf:rest N76be316800e3472fa1ea4579e44826de
119 N39d9cd59842545d79f0d26ee51f34363 schema:name Springer Nature - SN SciGraph project
120 rdf:type schema:Organization
121 N5a4cd611f26147d5a5697d6066349911 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Cell Culture Techniques
123 rdf:type schema:DefinedTerm
124 N65e845fcf0f24bc294e57499768229e8 rdf:first sg:person.014212754751.73
125 rdf:rest N24b3b14b0efd4350bc1cb76af49a58b9
126 N6bb6048501f0434fa7425d882bb2e874 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Osteogenesis
128 rdf:type schema:DefinedTerm
129 N74c3abbde5164b5c911347638f457318 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Mesenchymal Stem Cells
131 rdf:type schema:DefinedTerm
132 N76be316800e3472fa1ea4579e44826de rdf:first sg:person.0722061436.43
133 rdf:rest Nf1bb02ed952c40e7bcf113f5870d24ff
134 N8c0330b37657439a8fa39a07d243347a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Cryopreservation
136 rdf:type schema:DefinedTerm
137 N8e074af214624df9aa07fd9279f4bdcd schema:name dimensions_id
138 schema:value pub.1091220758
139 rdf:type schema:PropertyValue
140 Na1fa0e424aa44ce29e57e55249869f73 schema:name pubmed_id
141 schema:value 28815364
142 rdf:type schema:PropertyValue
143 Nb58801c8973443e7ba7fe5812e66671d schema:issueNumber 4
144 rdf:type schema:PublicationIssue
145 Nbc982ecc972e4b89b7af7025a907ec75 rdf:first sg:person.0773173167.40
146 rdf:rest N12f607071726436aba0eb8fd45a36912
147 Nc53604009cd243c69ec2a4beb102c54f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Bone and Bones
149 rdf:type schema:DefinedTerm
150 Nda1bb98e6ddd4e10bab16f2f05934b25 schema:name doi
151 schema:value 10.1007/s10561-017-9652-3
152 rdf:type schema:PropertyValue
153 Ndb8e0a0ec98b4e09bd0fb66f62d06197 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Humans
155 rdf:type schema:DefinedTerm
156 Ne2df8d85d32b4069a323d44667a53428 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Diastasis, Bone
158 rdf:type schema:DefinedTerm
159 Ne444ef76085641e2b0bf43b1525be07b rdf:first sg:person.01354672317.51
160 rdf:rest N27a0831dda6549d2bcba8b822ecc2fd5
161 Ne70c79f1e9264e76847be688b1639862 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Cell Proliferation
163 rdf:type schema:DefinedTerm
164 Nf1bb02ed952c40e7bcf113f5870d24ff rdf:first sg:person.01245756105.18
165 rdf:rest rdf:nil
166 Nfae397edb1aa4459aa3e519ef226d1b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Chondrogenesis
168 rdf:type schema:DefinedTerm
169 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
170 schema:name Medical and Health Sciences
171 rdf:type schema:DefinedTerm
172 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
173 schema:name Clinical Sciences
174 rdf:type schema:DefinedTerm
175 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
176 schema:name Neurosciences
177 rdf:type schema:DefinedTerm
178 sg:journal.1023785 schema:issn 1389-9333
179 1573-6814
180 schema:name Cell and Tissue Banking
181 schema:publisher Springer Nature
182 rdf:type schema:Periodical
183 sg:person.01245756105.18 schema:affiliation grid-institutes:None
184 schema:familyName Behravan
185 schema:givenName Javad
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245756105.18
187 rdf:type schema:Person
188 sg:person.01335211077.35 schema:affiliation grid-institutes:None
189 schema:familyName Heirani-Tabasi
190 schema:givenName Asieh
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335211077.35
192 rdf:type schema:Person
193 sg:person.01354672317.51 schema:affiliation grid-institutes:grid.411583.a
194 schema:familyName Kalalinia
195 schema:givenName Fatemeh
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354672317.51
197 rdf:type schema:Person
198 sg:person.014212754751.73 schema:affiliation grid-institutes:grid.411583.a
199 schema:familyName Toosi
200 schema:givenName Shirin
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014212754751.73
202 rdf:type schema:Person
203 sg:person.0673027625.55 schema:affiliation grid-institutes:None
204 schema:familyName Bahrami
205 schema:givenName Ahmad Reza
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673027625.55
207 rdf:type schema:Person
208 sg:person.0715547640.10 schema:affiliation grid-institutes:None
209 schema:familyName Naderi-Meshkin
210 schema:givenName Hojjat
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0715547640.10
212 rdf:type schema:Person
213 sg:person.0722061436.43 schema:affiliation grid-institutes:None
214 schema:familyName Mirahmadi
215 schema:givenName Mahdi
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722061436.43
217 rdf:type schema:Person
218 sg:person.0773173167.40 schema:affiliation grid-institutes:grid.260770.4
219 schema:familyName Hosseinkhani
220 schema:givenName Hossein
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773173167.40
222 rdf:type schema:Person
223 sg:pub.10.1007/bf00316069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039888162
224 https://doi.org/10.1007/bf00316069
225 rdf:type schema:CreativeWork
226 sg:pub.10.1007/s00264-004-0547-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033915925
227 https://doi.org/10.1007/s00264-004-0547-0
228 rdf:type schema:CreativeWork
229 sg:pub.10.1007/s00264-011-1338-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1030535452
230 https://doi.org/10.1007/s00264-011-1338-z
231 rdf:type schema:CreativeWork
232 sg:pub.10.1007/s10517-006-0214-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001751346
233 https://doi.org/10.1007/s10517-006-0214-0
234 rdf:type schema:CreativeWork
235 sg:pub.10.1038/6529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040720175
236 https://doi.org/10.1038/6529
237 rdf:type schema:CreativeWork
238 sg:pub.10.1038/sj.gt.3301760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034195992
239 https://doi.org/10.1038/sj.gt.3301760
240 rdf:type schema:CreativeWork
241 grid-institutes:None schema:alternateName Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad, Iran
242 Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran
243 schema:name Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
244 Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad, Iran
245 Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran
246 rdf:type schema:Organization
247 grid-institutes:grid.260770.4 schema:alternateName School of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan
248 schema:name School of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan
249 rdf:type schema:Organization
250 grid-institutes:grid.411583.a schema:alternateName Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
251 Department of Orthopedic Surgery, Orthopedic and Trauma Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
252 Medical Genetic Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran
253 schema:name Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
254 Department of Orthopedic Surgery, Orthopedic and Trauma Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
255 Medical Genetic Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran
256 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...