Advances of radiation sterilisation in tissue banking View Full Text


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Article Info

DATE

2017-10-11

AUTHORS

Norimah Yusof

ABSTRACT

Under the auspices of the IAEA tissue banking programme on “Radiation Sterilisation of Tissue Graft” conducted from 1985 to 2004, many scientists and surgeons were involved in various regional research and development (R&D) projects mainly in dealing with radiation dose selection, radiation effects on human tissues and quality system in radiation sterilisation. New findings on radiation effects, tissue processing and preservation were shared during the regional and interregional meetings and workshops. Many tissue banks started to use radiation (25 kGy) to sterilize tissue grafts for tissue safety and efficacy and still continue to use it. The IAEA Code of Practice for Radiation Sterilization of Tissues Allografts developed in 2007 offered simpler methods to conduct radiation dose setting and dose validation experiments for tissue grafts. Advances in dose selection and dose mapping are continued under the quality management system when banks need to be certified to continue their operation. The combination of good tissue processing and preservation as well as good radiation practice will ensure the tissue products are properly sterilised thus safe and of high quality. Experience in meeting challenges in using radiation sterilisation and achievements reported by the tissue bankers are shared here. More... »

PAGES

175-186

References to SciGraph publications

  • 2010-08-12. Synergetic effect of freeze-drying and gamma irradiation on the mechanical properties of human cancellous bone in CELL AND TISSUE BANKING
  • 2012-04-27. Effect of gamma irradiation on mechanical properties of human cortical bone: influence of different processing methods in CELL AND TISSUE BANKING
  • 2008-03-05. Validation of 15 kGy as a radiation sterilisation dose for bone allografts manufactured at the Queensland Bone Bank: application of the VDmax 15 method in CELL AND TISSUE BANKING
  • 2012-11-28. Scanning electron microscopic assessment on surface morphology of preserved human amniotic membrane after gamma sterilisation in CELL AND TISSUE BANKING
  • 2011-10-27. Irradiation Does Not Modify Mechanical Properties of Cancellous Bone Under Compression in CLINICAL ORTHOPAEDICS AND RELATED RESEARCH®
  • 2003-06. The International Atomic Energy Agency (IAEA) Programme in Radiation and Tissue Banking: Past, Present and Future in CELL AND TISSUE BANKING
  • 2010-05-28. Packin’ ya Eskies! in CELL AND TISSUE BANKING
  • 2008-04-23. Effect of low dose and moderate dose gamma irradiation on the mechanical properties of bone and soft tissue allografts in CELL AND TISSUE BANKING
  • 2014-03-28. Substantiation of 25 kGy radiation sterilization dose for banked air dried amniotic membrane and evaluation of personnel skill in influencing finished product bioburden in CELL AND TISSUE BANKING
  • 2006-07-05. The International Atomic Energy Agency (IAEA) Program on Radiation and Tissue Banking: a Successful Program for Developing Countries in CELL AND TISSUE BANKING
  • 2006-07-05. Validation and Substantiation of 25 kGy as Sterilization Dose for Lyophilized Human Amnion Membrane in CELL AND TISSUE BANKING
  • 2005-12. Validating a Low Dose Gamma Irradiation Process for Sterilizing Allografts Using ISO 11137 Method 2B in CELL AND TISSUE BANKING
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10561-017-9651-4

    DOI

    http://dx.doi.org/10.1007/s10561-017-9651-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1092166441

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29022196


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