Amniotic membrane in ophthalmology: properties, preparation, storage and indications for grafting—a review View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-03-02

AUTHORS

Katerina Jirsova, Gary L. A. Jones

ABSTRACT

The use of amniotic membrane in ophthalmic surgery and other surgical procedures in the fields of dermatology, plastic surgery, genitourinary medicine and otolaryngology is on the increase. Furthermore, amniotic membrane and its epithelial and mesenchymal cells have broad use in regenerative medicine and hold great promise in anticancer treatment. Amniotic membrane is a rich source of biologically active factors and as such, promotes healing and acts as an effective material for wound dressing. Amniotic membrane supports epithelialization and exhibits anti-fibrotic, anti-inflammatory, anti-angiogenic and anti-microbial features. Placentas utilised in the preparation of amniotic membrane are retrieved from donors undergoing elective caesarean section. Maternal blood must undergo serological screening at the time of donation and, in the absence of advanced diagnostic testing techniques, 6 months postpartum in order to cover the time window for the potential transmission of communicable diseases. Amniotic membrane is prepared by blunt dissection under strict aseptic conditions, then is typically transferred onto a nitrocellulose paper carrier, usually with the epithelial side up, and cut into multiple pieces of different dimensions. Amniotic membrane can be stored under various conditions, most often cryopreserved in glycerol or dimethyl sulfoxide or their mixture with culture medium or buffers. Other preservation methods include lyophilisation and air-drying. In ophthalmology, amniotic membrane is increasingly used for ocular surface reconstruction, including the treatment of persistent epithelial defects and non-healing corneal ulcers, corneal perforations and descemetoceles, bullous keratopathy, as well as corneal disorders with associated limbal stem cell deficiency, pterygium, conjunctival reconstruction, corneoscleral melts and perforations, and glaucoma surgeries. More... »

PAGES

193-204

References to SciGraph publications

  • 2006-04-13. Comparison of intact and denuded amniotic membrane as a substrate for cell-suspension culture of human limbal epithelial cells in GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • 2009-08-20. Comparison of cryopreserved and air-dried human amniotic membrane for ophthalmologic applications in GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • 2009-01-23. Amniotic membrane in ophthalmology: indications and limitations in EYE
  • 2016-07-18. Optimizing amniotic membrane tissue banking protocols for ophthalmic use in CELL AND TISSUE BANKING
  • 2012-03-11. A suitable and efficient procedure for the removal of decontaminating antibiotics from tissue allografts in CELL AND TISSUE BANKING
  • 2015-07-11. Amniotic membranes in ophthalmology: long term data on transplantation outcomes in CELL AND TISSUE BANKING
  • 2013-10-14. Human amniotic epithelial cells can differentiate into granulosa cells and restore folliculogenesis in a mouse model of chemotherapy-induced premature ovarian failure in STEM CELL RESEARCH & THERAPY
  • 2001-09. Further evaluation of amniotic membrane banking for transplantation in ocular surface diseases in CELL AND TISSUE BANKING
  • 2012-12-16. Amniotic membrane in oral and maxillofacial surgery in ORAL AND MAXILLOFACIAL SURGERY
  • 2012-11-28. Scanning electron microscopic assessment on surface morphology of preserved human amniotic membrane after gamma sterilisation in CELL AND TISSUE BANKING
  • 2014-02-16. A skin substitute based on human amniotic membrane in CELL AND TISSUE BANKING
  • 2012-05-18. Amniotic membrane: from structure and functions to clinical applications in CELL AND TISSUE RESEARCH
  • 2011-06-18. The effects of different preservation processes on the total protein and growth factor content in a new biological product developed from human amniotic membrane in CELL AND TISSUE BANKING
  • 2004-03. The Influence of Different Preservation and Sterilisation Steps on the Histological Properties of Amnion Allografts — Light and Scanning Electron Microscopic Studies in CELL AND TISSUE BANKING
  • 2004-06. Evaluation of Lyophilised, Gamma-Irradiated Amnion as a Biological Dressing in CELL AND TISSUE BANKING
  • 2000-01. Cryopreserved human amniotic membrane for ocular surface reconstruction in GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • 2015-12-09. Comparison of structural changes in skin and amnion tissue grafts for transplantation induced by gamma and electron beam irradiation for sterilization in CELL AND TISSUE BANKING
  • 1982-01. Expression of HLA antigens, β2-microglobulin and enzymes by human amniotic epithelial cells in NATURE
  • 2003-06. Properties of Air Dried Radiation Processed Amniotic Membranes under Different Storage Conditions in CELL AND TISSUE BANKING
  • 2016-04-12. Cytokine expression and ultrastructural alterations in fresh-frozen, freeze-dried and γ-irradiated human amniotic membranes in CELL AND TISSUE BANKING
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10561-017-9618-5

    DOI

    http://dx.doi.org/10.1007/s10561-017-9618-5

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1084025505

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28255771


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1113", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Ophthalmology and Optometry", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Amnion", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cryopreservation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Desiccation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Eye Diseases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Freeze Drying", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Ophthalmologic Surgical Procedures", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Pregnancy", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sterilization", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tissue Donors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tissue Preservation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tissue Scaffolds", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tissue and Organ Harvesting", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Laboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and 1st Faculty of Medicine, Charles University, Czech Republic, Ke Karlovu 2, 128 08, Prague 2, Czech Republic", 
              "id": "http://www.grid.ac/institutes/grid.4491.8", 
              "name": [
                "Laboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and 1st Faculty of Medicine, Charles University, Czech Republic, Ke Karlovu 2, 128 08, Prague 2, Czech Republic"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jirsova", 
            "givenName": "Katerina", 
            "id": "sg:person.01360341723.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360341723.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The Veneto Eye Bank Foundation, Padiglione Rama - Via Paccagnella n. 11, 30174, Zelarino, Venice, Italy", 
              "id": "http://www.grid.ac/institutes/grid.509584.5", 
              "name": [
                "The Veneto Eye Bank Foundation, Padiglione Rama - Via Paccagnella n. 11, 30174, Zelarino, Venice, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jones", 
            "givenName": "Gary L. A.", 
            "id": "sg:person.015013140717.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015013140717.30"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1023/b:catb.0000034076.16744.4b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013035329", 
              "https://doi.org/10.1023/b:catb.0000034076.16744.4b"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-014-9427-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036379687", 
              "https://doi.org/10.1007/s10561-014-9427-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-012-9305-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009155077", 
              "https://doi.org/10.1007/s10561-012-9305-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/scrt335", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010412145", 
              "https://doi.org/10.1186/scrt335"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1020158206073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035238869", 
              "https://doi.org/10.1023/a:1020158206073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-011-9261-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034001835", 
              "https://doi.org/10.1007/s10561-011-9261-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s004170050012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018958519", 
              "https://doi.org/10.1007/s004170050012"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-012-9353-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020920509", 
              "https://doi.org/10.1007/s10561-012-9353-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00441-012-1424-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015376243", 
              "https://doi.org/10.1007/s00441-012-1424-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-015-9536-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024596830", 
              "https://doi.org/10.1007/s10561-015-9536-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00417-005-0095-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043294130", 
              "https://doi.org/10.1007/s00417-005-0095-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-016-9553-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050230804", 
              "https://doi.org/10.1007/s10561-016-9553-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/295325a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003913437", 
              "https://doi.org/10.1038/295325a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10006-012-0382-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019536600", 
              "https://doi.org/10.1007/s10006-012-0382-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/eye.2008.410", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002035512", 
              "https://doi.org/10.1038/eye.2008.410"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00417-009-1162-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027638152", 
              "https://doi.org/10.1007/s00417-009-1162-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/b:catb.0000007030.72031.12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010431737", 
              "https://doi.org/10.1023/b:catb.0000007030.72031.12"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-015-9520-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017191578", 
              "https://doi.org/10.1007/s10561-015-9520-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10561-016-9568-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012431241", 
              "https://doi.org/10.1007/s10561-016-9568-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/b:catb.0000022276.47180.96", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017401663", 
              "https://doi.org/10.1023/b:catb.0000022276.47180.96"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2017-03-02", 
        "datePublishedReg": "2017-03-02", 
        "description": "The use of amniotic membrane in ophthalmic surgery and other surgical procedures in the fields of dermatology, plastic surgery, genitourinary medicine and otolaryngology is on the increase. Furthermore, amniotic membrane and its epithelial and mesenchymal cells have broad use in regenerative medicine and hold great promise in anticancer treatment. Amniotic membrane is a rich source of biologically active factors and as such, promotes healing and acts as an effective material for wound dressing. Amniotic membrane supports epithelialization and exhibits anti-fibrotic, anti-inflammatory, anti-angiogenic and anti-microbial features. Placentas utilised in the preparation of amniotic membrane are retrieved from donors undergoing elective caesarean section. Maternal blood must undergo serological screening at the time of donation and, in the absence of advanced diagnostic testing techniques, 6\u00a0months postpartum in order to cover the time window for the potential transmission of communicable diseases. Amniotic membrane is prepared by blunt dissection under strict aseptic conditions, then is typically transferred onto a nitrocellulose paper carrier, usually with the epithelial side up, and cut into multiple pieces of different dimensions. Amniotic membrane can be stored under various conditions, most often cryopreserved in glycerol or dimethyl sulfoxide or their mixture with culture medium or buffers. Other preservation methods include lyophilisation and air-drying. In ophthalmology, amniotic membrane is increasingly used for ocular surface reconstruction, including the treatment of persistent epithelial defects and non-healing corneal ulcers, corneal perforations and descemetoceles, bullous keratopathy, as well as corneal disorders with associated limbal stem cell deficiency, pterygium, conjunctival reconstruction, corneoscleral melts and perforations, and glaucoma surgeries.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s10561-017-9618-5", 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.6890757", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1023785", 
            "issn": [
              "1389-9333", 
              "1573-6814"
            ], 
            "name": "Cell and Tissue Banking", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "18"
          }
        ], 
        "keywords": [
          "amniotic membrane", 
          "non-healing corneal ulcers", 
          "limbal stem cell deficiency", 
          "elective caesarean section", 
          "persistent epithelial defects", 
          "time of donation", 
          "stem cell deficiency", 
          "strict aseptic conditions", 
          "ocular surface reconstruction", 
          "caesarean section", 
          "corneal perforation", 
          "bullous keratopathy", 
          "corneal ulcers", 
          "glaucoma surgery", 
          "epithelial defects", 
          "months postpartum", 
          "genitourinary medicine", 
          "maternal blood", 
          "serological screening", 
          "surgical procedures", 
          "diagnostic testing techniques", 
          "corneal disorders", 
          "cell deficiency", 
          "field of dermatology", 
          "blunt dissection", 
          "ophthalmic surgery", 
          "communicable diseases", 
          "anticancer treatment", 
          "surgery", 
          "anti-microbial features", 
          "plastic surgery", 
          "epithelial side", 
          "conjunctival reconstruction", 
          "potential transmission", 
          "mesenchymal cells", 
          "perforation", 
          "ophthalmology", 
          "treatment", 
          "active factors", 
          "aseptic conditions", 
          "medicine", 
          "descemetocele", 
          "keratopathy", 
          "culture medium", 
          "ulcers", 
          "pterygium", 
          "postpartum", 
          "placenta", 
          "disease", 
          "blood", 
          "otolaryngology", 
          "dissection", 
          "dermatology", 
          "epithelialization", 
          "disorders", 
          "wound dressings", 
          "healing", 
          "regenerative medicine", 
          "broad use", 
          "rich source", 
          "screening", 
          "deficiency", 
          "indications", 
          "preservation methods", 
          "membrane", 
          "cells", 
          "donation", 
          "dressing", 
          "review", 
          "donors", 
          "use", 
          "time window", 
          "reconstruction", 
          "factors", 
          "dimethyl sulfoxide", 
          "absence", 
          "great promise", 
          "increase", 
          "defects", 
          "procedure", 
          "preparation", 
          "transmission", 
          "promise", 
          "carriers", 
          "multiple pieces", 
          "conditions", 
          "time", 
          "paper carriers", 
          "side", 
          "features", 
          "sections", 
          "lyophilisation", 
          "glycerol", 
          "sulfoxide", 
          "technique", 
          "window", 
          "method", 
          "medium", 
          "materials", 
          "buffer", 
          "effective material", 
          "source", 
          "different dimensions", 
          "order", 
          "pieces", 
          "storage", 
          "dimensions", 
          "properties", 
          "mixture", 
          "testing techniques", 
          "field", 
          "surface reconstruction", 
          "melt"
        ], 
        "name": "Amniotic membrane in ophthalmology: properties, preparation, storage and indications for grafting\u2014a review", 
        "pagination": "193-204", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1084025505"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s10561-017-9618-5"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "28255771"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s10561-017-9618-5", 
          "https://app.dimensions.ai/details/publication/pub.1084025505"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-10-01T06:43", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_743.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s10561-017-9618-5"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9618-5'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9618-5'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9618-5'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10561-017-9618-5'


     

    This table displays all metadata directly associated to this object as RDF triples.

    326 TRIPLES      21 PREDICATES      173 URIs      145 LITERALS      22 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s10561-017-9618-5 schema:about N360830974c0a44be80faa6ca44cd2428
    2 N460987f1dda74c1c9edf8df651458c60
    3 N54b9b9f51253499fae0d80754ee58fb9
    4 N75e08e5661d248bbaab39d1371950ee0
    5 N798c32a1da694c00bcd97549ecb59624
    6 N930e66ca34654ae1b453b0b761cc0bec
    7 Nc74c4e5aa279442fbd68ebd2685d4ad0
    8 Nd7c359254aa64578b195aad48a0e1c96
    9 Ndd044acfaeab4d428e0f1a6295f9137f
    10 Nde513a6a10a247fdaaf9fa911c740ff0
    11 Ne342060176434996bf47b90f26ec28be
    12 Nec8e4086ebc14728af28feb4bef8acc0
    13 Neeec8dc645be4c429db1550a6ccc6cdc
    14 Nef7b2ebadfc84d13b95c931e9b5e2496
    15 Nf1cdded9f35d42f2a547f022189ed7f1
    16 anzsrc-for:11
    17 anzsrc-for:1113
    18 schema:author N1cbbd0e36b2942c09e4c49aed17740b6
    19 schema:citation sg:pub.10.1007/s00417-005-0095-3
    20 sg:pub.10.1007/s00417-009-1162-y
    21 sg:pub.10.1007/s004170050012
    22 sg:pub.10.1007/s00441-012-1424-6
    23 sg:pub.10.1007/s10006-012-0382-1
    24 sg:pub.10.1007/s10561-011-9261-5
    25 sg:pub.10.1007/s10561-012-9305-5
    26 sg:pub.10.1007/s10561-012-9353-x
    27 sg:pub.10.1007/s10561-014-9427-z
    28 sg:pub.10.1007/s10561-015-9520-y
    29 sg:pub.10.1007/s10561-015-9536-3
    30 sg:pub.10.1007/s10561-016-9553-x
    31 sg:pub.10.1007/s10561-016-9568-3
    32 sg:pub.10.1023/a:1020158206073
    33 sg:pub.10.1023/b:catb.0000007030.72031.12
    34 sg:pub.10.1023/b:catb.0000022276.47180.96
    35 sg:pub.10.1023/b:catb.0000034076.16744.4b
    36 sg:pub.10.1038/295325a0
    37 sg:pub.10.1038/eye.2008.410
    38 sg:pub.10.1186/scrt335
    39 schema:datePublished 2017-03-02
    40 schema:datePublishedReg 2017-03-02
    41 schema:description The use of amniotic membrane in ophthalmic surgery and other surgical procedures in the fields of dermatology, plastic surgery, genitourinary medicine and otolaryngology is on the increase. Furthermore, amniotic membrane and its epithelial and mesenchymal cells have broad use in regenerative medicine and hold great promise in anticancer treatment. Amniotic membrane is a rich source of biologically active factors and as such, promotes healing and acts as an effective material for wound dressing. Amniotic membrane supports epithelialization and exhibits anti-fibrotic, anti-inflammatory, anti-angiogenic and anti-microbial features. Placentas utilised in the preparation of amniotic membrane are retrieved from donors undergoing elective caesarean section. Maternal blood must undergo serological screening at the time of donation and, in the absence of advanced diagnostic testing techniques, 6 months postpartum in order to cover the time window for the potential transmission of communicable diseases. Amniotic membrane is prepared by blunt dissection under strict aseptic conditions, then is typically transferred onto a nitrocellulose paper carrier, usually with the epithelial side up, and cut into multiple pieces of different dimensions. Amniotic membrane can be stored under various conditions, most often cryopreserved in glycerol or dimethyl sulfoxide or their mixture with culture medium or buffers. Other preservation methods include lyophilisation and air-drying. In ophthalmology, amniotic membrane is increasingly used for ocular surface reconstruction, including the treatment of persistent epithelial defects and non-healing corneal ulcers, corneal perforations and descemetoceles, bullous keratopathy, as well as corneal disorders with associated limbal stem cell deficiency, pterygium, conjunctival reconstruction, corneoscleral melts and perforations, and glaucoma surgeries.
    42 schema:genre article
    43 schema:isAccessibleForFree false
    44 schema:isPartOf N3743976725794d2e818628e221281916
    45 Nfd286c9fada8470da306cd3ea7e8e033
    46 sg:journal.1023785
    47 schema:keywords absence
    48 active factors
    49 amniotic membrane
    50 anti-microbial features
    51 anticancer treatment
    52 aseptic conditions
    53 blood
    54 blunt dissection
    55 broad use
    56 buffer
    57 bullous keratopathy
    58 caesarean section
    59 carriers
    60 cell deficiency
    61 cells
    62 communicable diseases
    63 conditions
    64 conjunctival reconstruction
    65 corneal disorders
    66 corneal perforation
    67 corneal ulcers
    68 culture medium
    69 defects
    70 deficiency
    71 dermatology
    72 descemetocele
    73 diagnostic testing techniques
    74 different dimensions
    75 dimensions
    76 dimethyl sulfoxide
    77 disease
    78 disorders
    79 dissection
    80 donation
    81 donors
    82 dressing
    83 effective material
    84 elective caesarean section
    85 epithelial defects
    86 epithelial side
    87 epithelialization
    88 factors
    89 features
    90 field
    91 field of dermatology
    92 genitourinary medicine
    93 glaucoma surgery
    94 glycerol
    95 great promise
    96 healing
    97 increase
    98 indications
    99 keratopathy
    100 limbal stem cell deficiency
    101 lyophilisation
    102 materials
    103 maternal blood
    104 medicine
    105 medium
    106 melt
    107 membrane
    108 mesenchymal cells
    109 method
    110 mixture
    111 months postpartum
    112 multiple pieces
    113 non-healing corneal ulcers
    114 ocular surface reconstruction
    115 ophthalmic surgery
    116 ophthalmology
    117 order
    118 otolaryngology
    119 paper carriers
    120 perforation
    121 persistent epithelial defects
    122 pieces
    123 placenta
    124 plastic surgery
    125 postpartum
    126 potential transmission
    127 preparation
    128 preservation methods
    129 procedure
    130 promise
    131 properties
    132 pterygium
    133 reconstruction
    134 regenerative medicine
    135 review
    136 rich source
    137 screening
    138 sections
    139 serological screening
    140 side
    141 source
    142 stem cell deficiency
    143 storage
    144 strict aseptic conditions
    145 sulfoxide
    146 surface reconstruction
    147 surgery
    148 surgical procedures
    149 technique
    150 testing techniques
    151 time
    152 time of donation
    153 time window
    154 transmission
    155 treatment
    156 ulcers
    157 use
    158 window
    159 wound dressings
    160 schema:name Amniotic membrane in ophthalmology: properties, preparation, storage and indications for grafting—a review
    161 schema:pagination 193-204
    162 schema:productId N6efaeaa2919a4cdfae760229516c8554
    163 Na24600f82cb740dd92501947c073a26e
    164 Ndf5e513c0241446f8daf57ffe45ca5a6
    165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084025505
    166 https://doi.org/10.1007/s10561-017-9618-5
    167 schema:sdDatePublished 2022-10-01T06:43
    168 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    169 schema:sdPublisher Nb80030cd3b964f77b4e0f35b2f0ebaf8
    170 schema:url https://doi.org/10.1007/s10561-017-9618-5
    171 sgo:license sg:explorer/license/
    172 sgo:sdDataset articles
    173 rdf:type schema:ScholarlyArticle
    174 N1cbbd0e36b2942c09e4c49aed17740b6 rdf:first sg:person.01360341723.02
    175 rdf:rest Nb67b576b994c4c5b9993a70a33877b6d
    176 N360830974c0a44be80faa6ca44cd2428 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    177 schema:name Tissue Preservation
    178 rdf:type schema:DefinedTerm
    179 N3743976725794d2e818628e221281916 schema:volumeNumber 18
    180 rdf:type schema:PublicationVolume
    181 N460987f1dda74c1c9edf8df651458c60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    182 schema:name Amnion
    183 rdf:type schema:DefinedTerm
    184 N54b9b9f51253499fae0d80754ee58fb9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    185 schema:name Cryopreservation
    186 rdf:type schema:DefinedTerm
    187 N6efaeaa2919a4cdfae760229516c8554 schema:name doi
    188 schema:value 10.1007/s10561-017-9618-5
    189 rdf:type schema:PropertyValue
    190 N75e08e5661d248bbaab39d1371950ee0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    191 schema:name Desiccation
    192 rdf:type schema:DefinedTerm
    193 N798c32a1da694c00bcd97549ecb59624 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    194 schema:name Tissue Scaffolds
    195 rdf:type schema:DefinedTerm
    196 N930e66ca34654ae1b453b0b761cc0bec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    197 schema:name Humans
    198 rdf:type schema:DefinedTerm
    199 Na24600f82cb740dd92501947c073a26e schema:name dimensions_id
    200 schema:value pub.1084025505
    201 rdf:type schema:PropertyValue
    202 Nb67b576b994c4c5b9993a70a33877b6d rdf:first sg:person.015013140717.30
    203 rdf:rest rdf:nil
    204 Nb80030cd3b964f77b4e0f35b2f0ebaf8 schema:name Springer Nature - SN SciGraph project
    205 rdf:type schema:Organization
    206 Nc74c4e5aa279442fbd68ebd2685d4ad0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    207 schema:name Sterilization
    208 rdf:type schema:DefinedTerm
    209 Nd7c359254aa64578b195aad48a0e1c96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    210 schema:name Tissue and Organ Harvesting
    211 rdf:type schema:DefinedTerm
    212 Ndd044acfaeab4d428e0f1a6295f9137f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    213 schema:name Ophthalmologic Surgical Procedures
    214 rdf:type schema:DefinedTerm
    215 Nde513a6a10a247fdaaf9fa911c740ff0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    216 schema:name Freeze Drying
    217 rdf:type schema:DefinedTerm
    218 Ndf5e513c0241446f8daf57ffe45ca5a6 schema:name pubmed_id
    219 schema:value 28255771
    220 rdf:type schema:PropertyValue
    221 Ne342060176434996bf47b90f26ec28be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    222 schema:name Eye Diseases
    223 rdf:type schema:DefinedTerm
    224 Nec8e4086ebc14728af28feb4bef8acc0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    225 schema:name Animals
    226 rdf:type schema:DefinedTerm
    227 Neeec8dc645be4c429db1550a6ccc6cdc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    228 schema:name Pregnancy
    229 rdf:type schema:DefinedTerm
    230 Nef7b2ebadfc84d13b95c931e9b5e2496 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    231 schema:name Tissue Donors
    232 rdf:type schema:DefinedTerm
    233 Nf1cdded9f35d42f2a547f022189ed7f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    234 schema:name Female
    235 rdf:type schema:DefinedTerm
    236 Nfd286c9fada8470da306cd3ea7e8e033 schema:issueNumber 2
    237 rdf:type schema:PublicationIssue
    238 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    239 schema:name Medical and Health Sciences
    240 rdf:type schema:DefinedTerm
    241 anzsrc-for:1113 schema:inDefinedTermSet anzsrc-for:
    242 schema:name Ophthalmology and Optometry
    243 rdf:type schema:DefinedTerm
    244 sg:grant.6890757 http://pending.schema.org/fundedItem sg:pub.10.1007/s10561-017-9618-5
    245 rdf:type schema:MonetaryGrant
    246 sg:journal.1023785 schema:issn 1389-9333
    247 1573-6814
    248 schema:name Cell and Tissue Banking
    249 schema:publisher Springer Nature
    250 rdf:type schema:Periodical
    251 sg:person.01360341723.02 schema:affiliation grid-institutes:grid.4491.8
    252 schema:familyName Jirsova
    253 schema:givenName Katerina
    254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360341723.02
    255 rdf:type schema:Person
    256 sg:person.015013140717.30 schema:affiliation grid-institutes:grid.509584.5
    257 schema:familyName Jones
    258 schema:givenName Gary L. A.
    259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015013140717.30
    260 rdf:type schema:Person
    261 sg:pub.10.1007/s00417-005-0095-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043294130
    262 https://doi.org/10.1007/s00417-005-0095-3
    263 rdf:type schema:CreativeWork
    264 sg:pub.10.1007/s00417-009-1162-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1027638152
    265 https://doi.org/10.1007/s00417-009-1162-y
    266 rdf:type schema:CreativeWork
    267 sg:pub.10.1007/s004170050012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018958519
    268 https://doi.org/10.1007/s004170050012
    269 rdf:type schema:CreativeWork
    270 sg:pub.10.1007/s00441-012-1424-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015376243
    271 https://doi.org/10.1007/s00441-012-1424-6
    272 rdf:type schema:CreativeWork
    273 sg:pub.10.1007/s10006-012-0382-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019536600
    274 https://doi.org/10.1007/s10006-012-0382-1
    275 rdf:type schema:CreativeWork
    276 sg:pub.10.1007/s10561-011-9261-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034001835
    277 https://doi.org/10.1007/s10561-011-9261-5
    278 rdf:type schema:CreativeWork
    279 sg:pub.10.1007/s10561-012-9305-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009155077
    280 https://doi.org/10.1007/s10561-012-9305-5
    281 rdf:type schema:CreativeWork
    282 sg:pub.10.1007/s10561-012-9353-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020920509
    283 https://doi.org/10.1007/s10561-012-9353-x
    284 rdf:type schema:CreativeWork
    285 sg:pub.10.1007/s10561-014-9427-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1036379687
    286 https://doi.org/10.1007/s10561-014-9427-z
    287 rdf:type schema:CreativeWork
    288 sg:pub.10.1007/s10561-015-9520-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1017191578
    289 https://doi.org/10.1007/s10561-015-9520-y
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1007/s10561-015-9536-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024596830
    292 https://doi.org/10.1007/s10561-015-9536-3
    293 rdf:type schema:CreativeWork
    294 sg:pub.10.1007/s10561-016-9553-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050230804
    295 https://doi.org/10.1007/s10561-016-9553-x
    296 rdf:type schema:CreativeWork
    297 sg:pub.10.1007/s10561-016-9568-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012431241
    298 https://doi.org/10.1007/s10561-016-9568-3
    299 rdf:type schema:CreativeWork
    300 sg:pub.10.1023/a:1020158206073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035238869
    301 https://doi.org/10.1023/a:1020158206073
    302 rdf:type schema:CreativeWork
    303 sg:pub.10.1023/b:catb.0000007030.72031.12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010431737
    304 https://doi.org/10.1023/b:catb.0000007030.72031.12
    305 rdf:type schema:CreativeWork
    306 sg:pub.10.1023/b:catb.0000022276.47180.96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017401663
    307 https://doi.org/10.1023/b:catb.0000022276.47180.96
    308 rdf:type schema:CreativeWork
    309 sg:pub.10.1023/b:catb.0000034076.16744.4b schema:sameAs https://app.dimensions.ai/details/publication/pub.1013035329
    310 https://doi.org/10.1023/b:catb.0000034076.16744.4b
    311 rdf:type schema:CreativeWork
    312 sg:pub.10.1038/295325a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003913437
    313 https://doi.org/10.1038/295325a0
    314 rdf:type schema:CreativeWork
    315 sg:pub.10.1038/eye.2008.410 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002035512
    316 https://doi.org/10.1038/eye.2008.410
    317 rdf:type schema:CreativeWork
    318 sg:pub.10.1186/scrt335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010412145
    319 https://doi.org/10.1186/scrt335
    320 rdf:type schema:CreativeWork
    321 grid-institutes:grid.4491.8 schema:alternateName Laboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and 1st Faculty of Medicine, Charles University, Czech Republic, Ke Karlovu 2, 128 08, Prague 2, Czech Republic
    322 schema:name Laboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and 1st Faculty of Medicine, Charles University, Czech Republic, Ke Karlovu 2, 128 08, Prague 2, Czech Republic
    323 rdf:type schema:Organization
    324 grid-institutes:grid.509584.5 schema:alternateName The Veneto Eye Bank Foundation, Padiglione Rama - Via Paccagnella n. 11, 30174, Zelarino, Venice, Italy
    325 schema:name The Veneto Eye Bank Foundation, Padiglione Rama - Via Paccagnella n. 11, 30174, Zelarino, Venice, Italy
    326 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...