Disinfection of human musculoskeletal allografts in tissue banking: a systematic review View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12

AUTHORS

J. Mohr, M. Germain, M. Winters, S. Fraser, A. Duong, A. Garibaldi, N. Simunovic, D. Alsop, D. Dao, R. Bessemer, O. R. Ayeni, on behalf of the Bioburden Steering Committee and Musculoskeletal Tissue Working group

ABSTRACT

Musculoskeletal allografts are typically disinfected using antibiotics, irradiation or chemical methods but protocols vary significantly between tissue banks. It is likely that different disinfection protocols will not have the same level of microorganism kill; they may also have varying effects on the structural integrity of the tissue, which could lead to significant differences in terms of clinical outcome in recipients. Ideally, a disinfection protocol should achieve the greatest bioburden reduction with the lowest possible impact on tissue integrity. A systematic review of three databases found 68 laboratory and clinical studies that analyzed the microbial bioburden or contamination rates of musculoskeletal allografts. The use of peracetic acid-ethanol or ionizing radiation was found to be most effective for disinfection of tissues. The use of irradiation is the most frequently published method for the terminal sterilization of musculoskeletal allografts; it is widely used and its efficacy is well documented in the literature. However, effective disinfection results were still observed using the BioCleanse™ Tissue Sterilization process, pulsatile lavage with antibiotics, ethylene oxide, and chlorhexidine. The variety of effective methods to reduce contamination rate or bioburden, in conjunction with limited high quality evidence provides little support for the recommendation of a single bioburden reduction method. More... »

PAGES

573-584

References to SciGraph publications

  • 2012-01. A prospective randomized comparison of irradiated and non-irradiated hamstring tendon allograft for ACL reconstruction in KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
  • 2005-06. Biomechanical comparison of human bone-patellar tendon-bone grafts after sterilization with peracetic acid ethanol in CELL AND TISSUE BANKING
  • 2013-09. Evaluation of safety and efficacy of radiation-sterilized bone allografts in reconstructive oral surgery in CELL AND TISSUE BANKING
  • 2009-05. Femoral and acetabular revision using impacted nondemineralized freeze-dried bone allografts in JOURNAL OF ORTHOPAEDIC SCIENCE
  • 2012-03. Repeated Freeze-thaw Cycles Do Not Alter the Biomechanical Properties of Fibular Allograft Bone in CLINICAL ORTHOPAEDICS AND RELATED RESEARCH®
  • 2008-08. Radioprotectant and Radiosensitizer Effects on Sterility of γ-irradiated Bone in CLINICAL ORTHOPAEDICS AND RELATED RESEARCH®
  • 2008-06. Validation of 15 kGy as a radiation sterilisation dose for bone allografts manufactured at the Queensland Bone Bank: application of the VDmax 15 method in CELL AND TISSUE BANKING
  • 2009-07. Effectiveness of antibiotics and antiseptics on coagulase-negative staphylococci for the decontamination of bone allografts in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
  • 2002-12. Clinical Efficacy and Compatibility of Allogeneic Avital Tissue Transplants Sterilized with a Peracetic Acid/Ethanol Mixture in CELL AND TISSUE BANKING
  • 2011-11. Synergetic effect of freeze-drying and gamma irradiation on the mechanical properties of human cancellous bone in CELL AND TISSUE BANKING
  • 2005-12. Validating a Low Dose Gamma Irradiation Process for Sterilizing Allografts Using ISO 11137 Method 2B in CELL AND TISSUE BANKING
  • 2003-06. Reconstructing Tumour Defects: Lyophilised, Irradiated Bone Allografts in CELL AND TISSUE BANKING
  • 2011-11. Fractionation of high-dose electron beam irradiation of BPTB grafts provides significantly improved viscoelastic and structural properties compared to standard gamma irradiation in KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
  • 2012-09. Irradiation Does Not Modify Mechanical Properties of Cancellous Bone Under Compression in CLINICAL ORTHOPAEDICS AND RELATED RESEARCH®
  • 2004-09. Effects of a Peracetic Acid Disinfection Protocol on the Biocompatibility and Biomechanical Properties of Human Patellar Tendon Allografts in CELL AND TISSUE BANKING
  • 2007-09. Effects of gamma irradiation on mechanical properties of defatted trabecular bone allografts assessed by speed-of-sound measurement in CELL AND TISSUE BANKING
  • 2001-11. Effects of freezing/thawing on the biomechanical properties of human tendons in SURGICAL AND RADIOLOGIC ANATOMY
  • 2012-08. Analysis of predisposing factors for contamination of bone and tendon allografts in CELL AND TISSUE BANKING
  • 2008-12. Effect of low dose and moderate dose gamma irradiation on the mechanical properties of bone and soft tissue allografts in CELL AND TISSUE BANKING
  • 2010-08. Bacterial Colonization of Bone Allografts: Establishment and Effects of Antibiotics in CLINICAL ORTHOPAEDICS AND RELATED RESEARCH®
  • 2009-08. Mechanical properties of radiation-sterilised human Bone-Tendon-Bone grafts preserved by different methods in CELL AND TISSUE BANKING
  • 2013-09. Aseptically processed and chemically sterilized BTB allografts for anterior cruciate ligament reconstruction: a prospective randomized study in KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
  • 2007-06. Development of a bacteriophage model system to investigate virus inactivation methods used in the treatment of bone allografts in CELL AND TISSUE BANKING
  • 2009-05. Anterior cruciate ligament reconstruction with BPTB autograft, irradiated versus non-irradiated allograft: a prospective randomized clinical study in KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
  • 2008-04. Effects of freezing on the biomechanical and structural properties of human posterior tibial tendons in INTERNATIONAL ORTHOPAEDICS
  • 2011-12. Radiation and Ethylene Oxide Terminal Sterilization Experiences with Drug Eluting Stent Products in AAPS PHARMSCITECH
  • 2012-08. Effect of accelerated electron beam on mechanical properties of human cortical bone: influence of different processing methods in CELL AND TISSUE BANKING
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10561-016-9584-3

    DOI

    http://dx.doi.org/10.1007/s10561-016-9584-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010126929

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27665294


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