Evaluation of new antibiotic cocktails against contaminating bacteria found in allograft tissues View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12

AUTHORS

Agnese Serafini, Erika Riello, Diletta Trojan, Elisa Cogliati, Giorgio Palù, Riccardo Manganelli, Adolfo Paolin

ABSTRACT

Contamination of retrieved tissues is a major problem for allograft safety. Consequently, tissue banks have implemented decontamination protocols to eliminate microorganisms from tissues. Despite the widespread adoption of these protocols, few comprehensive studies validating such methods have been published. In this manuscript we compare the bactericidal activity of different antibiotic cocktails at different temperatures against a panel of bacterial species frequently isolated in allograft tissues collected at the Treviso Tissue Bank Foundation, a reference organization of the Veneto Region in Italy that was instituted to select, recover, process, store and distribute human tissues. We were able to identify at least two different formulations capable of killing most of the bacteria during prolonged incubation at 4 °C. More... »

PAGES

619-628

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10561-016-9581-6

DOI

http://dx.doi.org/10.1007/s10561-016-9581-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015087677

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27604467


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