Stem cells from fetal membranes and amniotic fluid: markers for cell isolation and therapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-06

AUTHORS

Michela Pozzobon, Martina Piccoli, Paolo De Coppi

ABSTRACT

Stem cell therapy is in constant need of new cell sources to conceive regenerative medicine approaches for diseases that are still without therapy. Scientists drew the attention toward amniotic membrane and amniotic fluid stem cells, since these sources possess many advantages: first of all as cells can be extracted from discarded foetal material it is inexpensive, secondly abundant stem cells can be obtained and finally, these stem cell sources are free from ethical considerations. Many studies have demonstrated the differentiation potential in vitro and in vivo toward mesenchymal and non-mesenchymal cell types; in addition the immune-modulatory properties make these cells a good candidate for allo- and xenotransplantation. This review offers an overview on markers characterisation and on the latest findings in pre-clinical or clinical setting of the stem cell populations isolated from these sources. More... »

PAGES

199-211

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10561-014-9428-y

DOI

http://dx.doi.org/10.1007/s10561-014-9428-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042033791

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24554400


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