Preformed Angiotensin II is Present in Human Mast Cells View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-11

AUTHORS

Masatake Hara, Koh Ono, Hiromi Wada, Shigetake Sasayama, Akira Matsumori

ABSTRACT

Purpose The density of mast cells increases in the myocardium of patients suffering from heart failure. However, their function remains unclear. In this study, preformed angiotensin II (ANG II), a potent growth factor, was found to be contained in, and released by, human mast cells.Methods: The human mast cell line (HMC-1) was incubated with 0 to 10−6 M calcitonin gene-related peptide (CGRP) or culture medium. The expression of renin-angiotensin system mRNA was examined using RT-PCR analysis. ELISA and immunohistochemistry with monoclonal antibody against human ANG II were performed to detect the presence of ANG II in HMC-1. The effect of CGRP on the expression of angiotensinogen mRNA was examined by quantitative RT-PCR analysis.Results: Preformed ANG II was detected in a human mast cell line (HMC-1) which is a neoplastic cell line of mast cells by ELISA and immunohistochemistry. Presence of mRNA of angiotensinogen and renin was confirmed by polymerase chain reaction in HMC-1, while mRNA of angiotensin converting enzyme (ACE) was undetectable. Since myocardial mast cells are interfaced with nerve fibers and functionally associated with CGRP, the effect of CGRP on ANG II release from HMC-1 was examined. CGRP induced the release of ANG II and increased angiotensinogen mRNA in HMC-1.Conclusions The presence of preformed ANG II and gene expression of the renin-angiotensin system were detected in human mast cells. The release and synthesis of ANG II in mast cells was regulated by CGRP. More... »

PAGES

415-420

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10557-004-6218-y

DOI

http://dx.doi.org/10.1007/s10557-004-6218-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022931766

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15770428


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Angiotensin II", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcitonin Gene-Related Peptide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enzyme-Linked Immunosorbent Assay", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia, Mast-Cell", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mast Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rabbits", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renin-Angiotensin System", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hara", 
        "givenName": "Masatake", 
        "id": "sg:person.0607066624.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607066624.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ono", 
        "givenName": "Koh", 
        "id": "sg:person.01070333054.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070333054.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Thoracic Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Thoracic Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wada", 
        "givenName": "Hiromi", 
        "id": "sg:person.011252066622.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011252066622.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sasayama", 
        "givenName": "Shigetake", 
        "id": "sg:person.0771215563.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771215563.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kyoto University, 54 Kawaracho Shogoin, 606-8397, Sakyo-ku, Kyoto, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan", 
            "Department of Cardiovascular Medicine, Kyoto University, 54 Kawaracho Shogoin, 606-8397, Sakyo-ku, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsumori", 
        "givenName": "Akira", 
        "id": "sg:person.01135443703.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01135443703.32"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1023/a:1020776807187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018939459", 
          "https://doi.org/10.1023/a:1020776807187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00327753", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017941951", 
          "https://doi.org/10.1007/bf00327753"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2004-11", 
    "datePublishedReg": "2004-11-01", 
    "description": "Purpose The density of mast cells increases in the myocardium of patients suffering from heart failure. However, their function remains unclear. In this study, preformed angiotensin II (ANG II), a potent growth factor, was found to be contained in, and released by, human mast cells.Methods: The human mast cell line (HMC-1) was incubated with 0 to 10\u22126 M calcitonin gene-related peptide (CGRP) or culture medium. The expression of renin-angiotensin system mRNA was examined using RT-PCR analysis. ELISA and immunohistochemistry with monoclonal antibody against human ANG II were performed to detect the presence of ANG II in HMC-1. The effect of CGRP on the expression of angiotensinogen mRNA was examined by quantitative RT-PCR analysis.Results: Preformed ANG II was detected in a human mast cell line (HMC-1) which is a neoplastic cell line of mast cells by ELISA and immunohistochemistry. Presence of mRNA of angiotensinogen and renin was confirmed by polymerase chain reaction in HMC-1, while mRNA of angiotensin converting enzyme (ACE) was undetectable. Since myocardial mast cells are interfaced with nerve fibers and functionally associated with CGRP, the effect of CGRP on ANG II release from HMC-1 was examined. CGRP induced the release of ANG II and increased angiotensinogen mRNA in HMC-1.Conclusions The presence of preformed ANG II and gene expression of the renin-angiotensin system were detected in human mast cells. The release and synthesis of ANG II in mast cells was regulated by CGRP.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s10557-004-6218-y", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1097576", 
        "issn": [
          "0920-3206", 
          "1573-7241"
        ], 
        "name": "Cardiovascular Drugs and Therapy", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "keywords": [
      "calcitonin gene-related peptide", 
      "effect of CGRP", 
      "human mast cells", 
      "human mast cell line", 
      "Ang II", 
      "mast cells", 
      "angiotensin converting enzyme", 
      "mast cell line", 
      "HMC-1", 
      "angiotensin II", 
      "angiotensinogen mRNA", 
      "M calcitonin gene-related peptide", 
      "RT-PCR analysis", 
      "cell lines", 
      "human ANG II", 
      "Ang II release", 
      "renin-angiotensin system", 
      "myocardium of patients", 
      "gene-related peptide", 
      "myocardial mast cells", 
      "presence of mRNA", 
      "potent growth factor", 
      "heart failure", 
      "polymerase chain reaction", 
      "nerve fibers", 
      "neoplastic cell lines", 
      "converting enzyme", 
      "monoclonal antibodies", 
      "growth factor", 
      "quantitative RT-PCR analysis", 
      "chain reaction", 
      "immunohistochemistry", 
      "ELISA", 
      "mRNA", 
      "cells", 
      "expression", 
      "gene expression", 
      "release", 
      "culture medium", 
      "patients", 
      "renin", 
      "angiotensinogen", 
      "myocardium", 
      "antibodies", 
      "presence", 
      "effect", 
      "failure", 
      "peptides", 
      "lines", 
      "factors", 
      "study", 
      "analysis", 
      "enzyme", 
      "purpose", 
      "function", 
      "fibers", 
      "reaction", 
      "medium", 
      "synthesis", 
      "system", 
      "density"
    ], 
    "name": "Preformed Angiotensin II is Present in Human Mast Cells", 
    "pagination": "415-420", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1022931766"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10557-004-6218-y"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15770428"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10557-004-6218-y", 
      "https://app.dimensions.ai/details/publication/pub.1022931766"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:32", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_390.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s10557-004-6218-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10557-004-6218-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10557-004-6218-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10557-004-6218-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10557-004-6218-y'


 

This table displays all metadata directly associated to this object as RDF triples.

214 TRIPLES      21 PREDICATES      102 URIs      92 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10557-004-6218-y schema:about N0e0062f22ade4fa7a137c56a459a5834
2 N1b9a624b8c914913b81860cba7418522
3 N234e68a99dbc44d5bdd7e48287b386c9
4 N30c3d9d7c438414b89122dfca8751ecc
5 N37bab5bc902f4f95bf85c08cca6c84ce
6 N3fa43c06c2654c62ad40eee2ddd0fc8d
7 N5b7b4d3f9c4549a0b8e0f4430f92d36f
8 N66655afc2b3b417584059ae9d0dda48e
9 N747efdf428a54e55b9f1b2307eac8bb5
10 N8833e90d647344be80b6ba085bdc2fa7
11 N93853d957c3b4abb8e63a6808e6ad4b2
12 Na8a63364a7704d14ba718b2b8d5e9f48
13 Ne82d7765d69e4bd2a4c7f14b48cc4332
14 anzsrc-for:11
15 anzsrc-for:1102
16 schema:author Nd8ddfb7ba33c4ec78e823c8483e1bd2b
17 schema:citation sg:pub.10.1007/bf00327753
18 sg:pub.10.1023/a:1020776807187
19 schema:datePublished 2004-11
20 schema:datePublishedReg 2004-11-01
21 schema:description Purpose The density of mast cells increases in the myocardium of patients suffering from heart failure. However, their function remains unclear. In this study, preformed angiotensin II (ANG II), a potent growth factor, was found to be contained in, and released by, human mast cells.Methods: The human mast cell line (HMC-1) was incubated with 0 to 10−6 M calcitonin gene-related peptide (CGRP) or culture medium. The expression of renin-angiotensin system mRNA was examined using RT-PCR analysis. ELISA and immunohistochemistry with monoclonal antibody against human ANG II were performed to detect the presence of ANG II in HMC-1. The effect of CGRP on the expression of angiotensinogen mRNA was examined by quantitative RT-PCR analysis.Results: Preformed ANG II was detected in a human mast cell line (HMC-1) which is a neoplastic cell line of mast cells by ELISA and immunohistochemistry. Presence of mRNA of angiotensinogen and renin was confirmed by polymerase chain reaction in HMC-1, while mRNA of angiotensin converting enzyme (ACE) was undetectable. Since myocardial mast cells are interfaced with nerve fibers and functionally associated with CGRP, the effect of CGRP on ANG II release from HMC-1 was examined. CGRP induced the release of ANG II and increased angiotensinogen mRNA in HMC-1.Conclusions The presence of preformed ANG II and gene expression of the renin-angiotensin system were detected in human mast cells. The release and synthesis of ANG II in mast cells was regulated by CGRP.
22 schema:genre article
23 schema:isAccessibleForFree false
24 schema:isPartOf N31a0a1532fc14dff862fbd0aedff67cc
25 N43730710f58f4b3280bc3d570f80cbf5
26 sg:journal.1097576
27 schema:keywords Ang II
28 Ang II release
29 ELISA
30 HMC-1
31 M calcitonin gene-related peptide
32 RT-PCR analysis
33 analysis
34 angiotensin II
35 angiotensin converting enzyme
36 angiotensinogen
37 angiotensinogen mRNA
38 antibodies
39 calcitonin gene-related peptide
40 cell lines
41 cells
42 chain reaction
43 converting enzyme
44 culture medium
45 density
46 effect
47 effect of CGRP
48 enzyme
49 expression
50 factors
51 failure
52 fibers
53 function
54 gene expression
55 gene-related peptide
56 growth factor
57 heart failure
58 human ANG II
59 human mast cell line
60 human mast cells
61 immunohistochemistry
62 lines
63 mRNA
64 mast cell line
65 mast cells
66 medium
67 monoclonal antibodies
68 myocardial mast cells
69 myocardium
70 myocardium of patients
71 neoplastic cell lines
72 nerve fibers
73 patients
74 peptides
75 polymerase chain reaction
76 potent growth factor
77 presence
78 presence of mRNA
79 purpose
80 quantitative RT-PCR analysis
81 reaction
82 release
83 renin
84 renin-angiotensin system
85 study
86 synthesis
87 system
88 schema:name Preformed Angiotensin II is Present in Human Mast Cells
89 schema:pagination 415-420
90 schema:productId Ncce714374a7940d09c90e054c494fb2e
91 Nf1e98f6d0a764e06bd6b104766e78103
92 Nfe3ccedf60a543a3b40df2c8eae5a5ce
93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022931766
94 https://doi.org/10.1007/s10557-004-6218-y
95 schema:sdDatePublished 2022-10-01T06:32
96 schema:sdLicense https://scigraph.springernature.com/explorer/license/
97 schema:sdPublisher N29ab1a188283494c99de12deeccfdbd1
98 schema:url https://doi.org/10.1007/s10557-004-6218-y
99 sgo:license sg:explorer/license/
100 sgo:sdDataset articles
101 rdf:type schema:ScholarlyArticle
102 N0bc48fc4be6e47d7b535c120b9ab8cf5 rdf:first sg:person.01135443703.32
103 rdf:rest rdf:nil
104 N0dd844c144604e8e8b59b88f98d46caf rdf:first sg:person.011252066622.02
105 rdf:rest N5eb5f2d496aa437fa28be2b39987bbb5
106 N0e0062f22ade4fa7a137c56a459a5834 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Cell Line, Tumor
108 rdf:type schema:DefinedTerm
109 N1b9a624b8c914913b81860cba7418522 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Enzyme-Linked Immunosorbent Assay
111 rdf:type schema:DefinedTerm
112 N234e68a99dbc44d5bdd7e48287b386c9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Rabbits
114 rdf:type schema:DefinedTerm
115 N29ab1a188283494c99de12deeccfdbd1 schema:name Springer Nature - SN SciGraph project
116 rdf:type schema:Organization
117 N30c3d9d7c438414b89122dfca8751ecc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Angiotensin II
119 rdf:type schema:DefinedTerm
120 N31a0a1532fc14dff862fbd0aedff67cc schema:volumeNumber 18
121 rdf:type schema:PublicationVolume
122 N37bab5bc902f4f95bf85c08cca6c84ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Animals
124 rdf:type schema:DefinedTerm
125 N3fa43c06c2654c62ad40eee2ddd0fc8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Mast Cells
127 rdf:type schema:DefinedTerm
128 N43730710f58f4b3280bc3d570f80cbf5 schema:issueNumber 6
129 rdf:type schema:PublicationIssue
130 N5b7b4d3f9c4549a0b8e0f4430f92d36f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Humans
132 rdf:type schema:DefinedTerm
133 N5eb5f2d496aa437fa28be2b39987bbb5 rdf:first sg:person.0771215563.82
134 rdf:rest N0bc48fc4be6e47d7b535c120b9ab8cf5
135 N66655afc2b3b417584059ae9d0dda48e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name RNA, Messenger
137 rdf:type schema:DefinedTerm
138 N747efdf428a54e55b9f1b2307eac8bb5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Calcitonin Gene-Related Peptide
140 rdf:type schema:DefinedTerm
141 N8833e90d647344be80b6ba085bdc2fa7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Immunohistochemistry
143 rdf:type schema:DefinedTerm
144 N93853d957c3b4abb8e63a6808e6ad4b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Renin-Angiotensin System
146 rdf:type schema:DefinedTerm
147 N95afb544eff540b5a2f0a86b761e1ab8 rdf:first sg:person.01070333054.04
148 rdf:rest N0dd844c144604e8e8b59b88f98d46caf
149 Na8a63364a7704d14ba718b2b8d5e9f48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Gene Expression
151 rdf:type schema:DefinedTerm
152 Ncce714374a7940d09c90e054c494fb2e schema:name pubmed_id
153 schema:value 15770428
154 rdf:type schema:PropertyValue
155 Nd8ddfb7ba33c4ec78e823c8483e1bd2b rdf:first sg:person.0607066624.12
156 rdf:rest N95afb544eff540b5a2f0a86b761e1ab8
157 Ne82d7765d69e4bd2a4c7f14b48cc4332 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Leukemia, Mast-Cell
159 rdf:type schema:DefinedTerm
160 Nf1e98f6d0a764e06bd6b104766e78103 schema:name doi
161 schema:value 10.1007/s10557-004-6218-y
162 rdf:type schema:PropertyValue
163 Nfe3ccedf60a543a3b40df2c8eae5a5ce schema:name dimensions_id
164 schema:value pub.1022931766
165 rdf:type schema:PropertyValue
166 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
167 schema:name Medical and Health Sciences
168 rdf:type schema:DefinedTerm
169 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
170 schema:name Cardiorespiratory Medicine and Haematology
171 rdf:type schema:DefinedTerm
172 sg:journal.1097576 schema:issn 0920-3206
173 1573-7241
174 schema:name Cardiovascular Drugs and Therapy
175 schema:publisher Springer Nature
176 rdf:type schema:Periodical
177 sg:person.01070333054.04 schema:affiliation grid-institutes:grid.258799.8
178 schema:familyName Ono
179 schema:givenName Koh
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070333054.04
181 rdf:type schema:Person
182 sg:person.011252066622.02 schema:affiliation grid-institutes:grid.258799.8
183 schema:familyName Wada
184 schema:givenName Hiromi
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011252066622.02
186 rdf:type schema:Person
187 sg:person.01135443703.32 schema:affiliation grid-institutes:grid.258799.8
188 schema:familyName Matsumori
189 schema:givenName Akira
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01135443703.32
191 rdf:type schema:Person
192 sg:person.0607066624.12 schema:affiliation grid-institutes:grid.258799.8
193 schema:familyName Hara
194 schema:givenName Masatake
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607066624.12
196 rdf:type schema:Person
197 sg:person.0771215563.82 schema:affiliation grid-institutes:grid.258799.8
198 schema:familyName Sasayama
199 schema:givenName Shigetake
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771215563.82
201 rdf:type schema:Person
202 sg:pub.10.1007/bf00327753 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017941951
203 https://doi.org/10.1007/bf00327753
204 rdf:type schema:CreativeWork
205 sg:pub.10.1023/a:1020776807187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018939459
206 https://doi.org/10.1023/a:1020776807187
207 rdf:type schema:CreativeWork
208 grid-institutes:grid.258799.8 schema:alternateName Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
209 Department of Cardiovascular Medicine, Kyoto University, 54 Kawaracho Shogoin, 606-8397, Sakyo-ku, Kyoto, Japan
210 Department of Thoracic Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan
211 schema:name Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
212 Department of Cardiovascular Medicine, Kyoto University, 54 Kawaracho Shogoin, 606-8397, Sakyo-ku, Kyoto, Japan
213 Department of Thoracic Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan
214 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...