Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-11-25

AUTHORS

Vivian P. Kamphuis, Jos J. M. Westenberg, Roel L. F. van der Palen, Nico A. Blom, Albert de Roos, Rob van der Geest, Mohammed S. M. Elbaz, Arno A. W. Roest

ABSTRACT

Knowledge of normal and abnormal flow patterns in the human cardiovascular system increases our understanding of normal physiology and may help unravel the complex pathophysiological mechanisms leading to cardiovascular disease. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has emerged as a suitable technique that enables visualization of in vivo blood flow patterns and quantification of parameters that could potentially be of prognostic value in the disease process. In this review, current image processing tools that are used for comprehensive visualization and quantification of blood flow and energy distribution in the heart and great vessels will be discussed. Also, imaging biomarkers extracted from 4D flow CMR will be reviewed that have been shown to distinguish between normal and abnormal flow patterns. Furthermore, current applications of 4D flow CMR in the heart and great vessels will be discussed, showing its potential as an additional diagnostic modality which could aid in disease management and timing of surgical intervention. More... »

PAGES

1069-1081

References to SciGraph publications

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  • 2010-01-14. Flow measurement by cardiovascular magnetic resonance: a multi-centre multi-vendor study of background phase offset errors that can compromise the accuracy of derived regurgitant or shunt flow measurements in JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
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  • 2000-04. Asymmetric redirection of flow through the heart in NATURE
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  • 2012-02-07. 4D cardiovascular magnetic resonance velocity mapping of alterations of right heart flow patterns and main pulmonary artery hemodynamics in tetralogy of Fallot in JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
  • 2016-05-31. Age dependence of pulmonary artery blood flow measured by 4D flow cardiovascular magnetic resonance: results of a population-based study in JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
  • 2012-11-14. Normal values of aortic dimensions, distensibility, and pulse wave velocity in children and young adults: a cross-sectional study in JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
  • 2016-01-28. Assessment of left and right atrial 3D hemodynamics in patients with atrial fibrillation: a 4D flow MRI study in THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
  • 2012-03-07. Describing the Highly Three Dimensional Right Ventricle Flow in ANNALS OF BIOMEDICAL ENGINEERING
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10554-016-1031-9

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    36 schema:description Knowledge of normal and abnormal flow patterns in the human cardiovascular system increases our understanding of normal physiology and may help unravel the complex pathophysiological mechanisms leading to cardiovascular disease. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has emerged as a suitable technique that enables visualization of in vivo blood flow patterns and quantification of parameters that could potentially be of prognostic value in the disease process. In this review, current image processing tools that are used for comprehensive visualization and quantification of blood flow and energy distribution in the heart and great vessels will be discussed. Also, imaging biomarkers extracted from 4D flow CMR will be reviewed that have been shown to distinguish between normal and abnormal flow patterns. Furthermore, current applications of 4D flow CMR in the heart and great vessels will be discussed, showing its potential as an additional diagnostic modality which could aid in disease management and timing of surgical intervention.
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