Patterns of myocardial perfusion in humans evaluated with contrast-enhanced 320 multidetector computed tomography View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-10

AUTHORS

J. Tobias Kühl, Jesper J. Linde, Andreas Fuchs, Thomas S. Kristensen, Henning Kelbæk, Richard T. George, Jens D. Hove, Klaus Fuglsang Kofoed

ABSTRACT

Left ventricular (LV) myocardial contrast enhancement can be recorded using 320 multi detector computed tomography (MDCT). We aimed to (1) assess patterns of regional myocardial perfusion at rest and compare them with NH(3) positron emission tomography (PET) (2) and to assess the effect of intravenous adenosine infusion on regional myocardial perfusion. To evaluate myocardial perfusion patterns at rest, we scanned 14 healthy subjects with PET and 14 age and gender matched subjects with 320 MDCT. To evaluate the effect of adenosine stress on relative perfusion patterns 14 subjects with near-normal epicardial coronary arteries were studied at rest and during adenosine stress. Relative perfusion was assessed as attenuation density (AD) in 16 segments of the LV, and each segment was divided into 3 layers: endo-, mid- and epi-cardial. During rest the relative AD by MDCT was lower in the lateral wall compared with the remainder of the LV (P < 0.002). A similar pattern was found by PET-imaging. LV endocardial AD was higher than mid- and epicardial AD (P < 0.05). At rest the endocardial/epicardial ratio in the septum was 0.99 compared with 1.23 in non-septal segments (P < 0.001). During adenosine infusion transmural AD increased due to significant increases in the mid- and epicardium and the endocardial/epicardial ratio decreased by 18% in non-septal segments (from 1.23 to 1.05 P < 0.001). Relative perfusion at rest is lower in the lateral wall of the LV with both PET and MDCT compared to the remainder of the myocardium. During adenosine stress endocardial/epicardial ratio decrease significantly. More... »

PAGES

1739-1747

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10554-011-9986-z

DOI

http://dx.doi.org/10.1007/s10554-011-9986-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050160560

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22143171


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenosine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Analysis of Variance", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coronary Circulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Ventricles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multidetector Computed Tomography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Myocardial Perfusion Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Positron-Emission Tomography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Predictive Value of Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reference Values", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vasodilator Agents", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "K\u00fchl", 
        "givenName": "J. Tobias", 
        "id": "sg:person.01001370400.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01001370400.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Copenhagen", 
          "id": "https://www.grid.ac/institutes/grid.5254.6", 
          "name": [
            "Department of Cardiology, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Linde", 
        "givenName": "Jesper J.", 
        "id": "sg:person.0706137677.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706137677.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fuchs", 
        "givenName": "Andreas", 
        "id": "sg:person.01131014113.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131014113.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kristensen", 
        "givenName": "Thomas S.", 
        "id": "sg:person.01150533044.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150533044.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kelb\u00e6k", 
        "givenName": "Henning", 
        "id": "sg:person.0771034557.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771034557.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Medicine, Johns Hopkins University, Baltimore, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "George", 
        "givenName": "Richard T.", 
        "id": "sg:person.01100661206.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100661206.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Copenhagen", 
          "id": "https://www.grid.ac/institutes/grid.5254.6", 
          "name": [
            "Department of Cardiology, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hove", 
        "givenName": "Jens D.", 
        "id": "sg:person.01136733117.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136733117.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark", 
            "Department of Radiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kofoed", 
        "givenName": "Klaus Fuglsang", 
        "id": "sg:person.016452166277.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016452166277.03"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1152/physrev.00045.2006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001000025"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181c4f535", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010033371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181c4f535", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010033371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181c4f535", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010033371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.09091014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010140910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12350-009-9156-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021153314", 
          "https://doi.org/10.1007/s12350-009-9156-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12350-009-9156-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021153314", 
          "https://doi.org/10.1007/s12350-009-9156-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(87)80083-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024102684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1011981526366", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026381728", 
          "https://doi.org/10.1023/a:1011981526366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2009.06.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028985969"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.2471070332", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030279036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2006.04.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033946852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circimaging.108.813766", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035827179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circimaging.108.813766", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035827179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181dfa2f2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036604988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181dfa2f2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036604988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e3181dfa2f2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036604988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10554-009-9531-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036804512", 
          "https://doi.org/10.1007/s10554-009-9531-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10554-009-9531-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036804512", 
          "https://doi.org/10.1007/s10554-009-9531-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10554-009-9531-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036804512", 
          "https://doi.org/10.1007/s10554-009-9531-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.10091399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040693172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.41.5.648", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043537925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.22538", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045195610"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e318124a884", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045237062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rli.0b013e318124a884", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045237062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.76.6.1262", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050887723"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.17.3.391", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053025551"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1992.73.6.2274", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075678894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076848166", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076848681", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082470357", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.1998.275.4.h1274", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083319418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.1998.275.4.h1274", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083319418"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2012-10", 
    "datePublishedReg": "2012-10-01", 
    "description": "Left ventricular (LV) myocardial contrast enhancement can be recorded using 320 multi detector computed tomography (MDCT). We aimed to (1) assess patterns of regional myocardial perfusion at rest and compare them with NH(3) positron emission tomography (PET) (2) and to assess the effect of intravenous adenosine infusion on regional myocardial perfusion. To evaluate myocardial perfusion patterns at rest, we scanned 14 healthy subjects with PET and 14 age and gender matched subjects with 320 MDCT. To evaluate the effect of adenosine stress on relative perfusion patterns 14 subjects with near-normal epicardial coronary arteries were studied at rest and during adenosine stress. Relative perfusion was assessed as attenuation density (AD) in 16 segments of the LV, and each segment was divided into 3 layers: endo-, mid- and epi-cardial. During rest the relative AD by MDCT was lower in the lateral wall compared with the remainder of the LV (P < 0.002). A similar pattern was found by PET-imaging. LV endocardial AD was higher than mid- and epicardial AD (P < 0.05). At rest the endocardial/epicardial ratio in the septum was 0.99 compared with 1.23 in non-septal segments (P < 0.001). During adenosine infusion transmural AD increased due to significant increases in the mid- and epicardium and the endocardial/epicardial ratio decreased by 18% in non-septal segments (from 1.23 to 1.05 P < 0.001). Relative perfusion at rest is lower in the lateral wall of the LV with both PET and MDCT compared to the remainder of the myocardium. During adenosine stress endocardial/epicardial ratio decrease significantly.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10554-011-9986-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1025429", 
        "issn": [
          "1569-5794", 
          "1573-0743"
        ], 
        "name": "The International Journal of Cardiovascular Imaging", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "28"
      }
    ], 
    "name": "Patterns of myocardial perfusion in humans evaluated with contrast-enhanced 320 multidetector computed tomography", 
    "pagination": "1739-1747", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "eef325ed474ffba08cbad79ccb1b879f11cf0973e7ae0e552588b8624f73d75a"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22143171"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100969716"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10554-011-9986-z"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050160560"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10554-011-9986-z", 
      "https://app.dimensions.ai/details/publication/pub.1050160560"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:08", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000516.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs10554-011-9986-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10554-011-9986-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10554-011-9986-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10554-011-9986-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10554-011-9986-z'


 

This table displays all metadata directly associated to this object as RDF triples.

245 TRIPLES      21 PREDICATES      63 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10554-011-9986-z schema:about N1c00c0833d5d4ec4a2ecc3b753e44b5c
2 N1e096b2ec6434c9e9e0084b542c989e8
3 N3527163e744d4577a98b135693f49b2c
4 N476361fcacae436095cfa7b680e2e859
5 N64cf85c84db747c698804cfec1d0adb3
6 N72f6b5892f024d6597f825d30e0ce7aa
7 N9f23394f4fb747b0964974db6bbb322d
8 Nb129e07951cd40d99a7bfbb691d6ea53
9 Nb4fd6f674af14d07b0a127177ed056f7
10 Nd77d9640a2ff4362acdd6e4b1b7e2a12
11 Ne5f0e967a4ba4c9591823d1fe9806034
12 anzsrc-for:11
13 anzsrc-for:1103
14 schema:author Nfa7effe1152646b5a9b47ce8c57980ac
15 schema:citation sg:pub.10.1007/s10554-009-9531-5
16 sg:pub.10.1007/s12350-009-9156-z
17 sg:pub.10.1023/a:1011981526366
18 https://app.dimensions.ai/details/publication/pub.1076848166
19 https://app.dimensions.ai/details/publication/pub.1076848681
20 https://app.dimensions.ai/details/publication/pub.1082470357
21 https://doi.org/10.1002/mrm.22538
22 https://doi.org/10.1016/j.jacc.2006.04.014
23 https://doi.org/10.1016/j.jacc.2009.06.014
24 https://doi.org/10.1016/s0735-1097(87)80083-9
25 https://doi.org/10.1097/rli.0b013e318124a884
26 https://doi.org/10.1097/rli.0b013e3181c4f535
27 https://doi.org/10.1097/rli.0b013e3181dfa2f2
28 https://doi.org/10.1148/radiol.09091014
29 https://doi.org/10.1148/radiol.10091399
30 https://doi.org/10.1148/radiol.2471070332
31 https://doi.org/10.1152/ajpheart.1998.275.4.h1274
32 https://doi.org/10.1152/jappl.1992.73.6.2274
33 https://doi.org/10.1152/physrev.00045.2006
34 https://doi.org/10.1161/01.cir.17.3.391
35 https://doi.org/10.1161/01.cir.76.6.1262
36 https://doi.org/10.1161/01.res.41.5.648
37 https://doi.org/10.1161/circimaging.108.813766
38 schema:datePublished 2012-10
39 schema:datePublishedReg 2012-10-01
40 schema:description Left ventricular (LV) myocardial contrast enhancement can be recorded using 320 multi detector computed tomography (MDCT). We aimed to (1) assess patterns of regional myocardial perfusion at rest and compare them with NH(3) positron emission tomography (PET) (2) and to assess the effect of intravenous adenosine infusion on regional myocardial perfusion. To evaluate myocardial perfusion patterns at rest, we scanned 14 healthy subjects with PET and 14 age and gender matched subjects with 320 MDCT. To evaluate the effect of adenosine stress on relative perfusion patterns 14 subjects with near-normal epicardial coronary arteries were studied at rest and during adenosine stress. Relative perfusion was assessed as attenuation density (AD) in 16 segments of the LV, and each segment was divided into 3 layers: endo-, mid- and epi-cardial. During rest the relative AD by MDCT was lower in the lateral wall compared with the remainder of the LV (P < 0.002). A similar pattern was found by PET-imaging. LV endocardial AD was higher than mid- and epicardial AD (P < 0.05). At rest the endocardial/epicardial ratio in the septum was 0.99 compared with 1.23 in non-septal segments (P < 0.001). During adenosine infusion transmural AD increased due to significant increases in the mid- and epicardium and the endocardial/epicardial ratio decreased by 18% in non-septal segments (from 1.23 to 1.05 P < 0.001). Relative perfusion at rest is lower in the lateral wall of the LV with both PET and MDCT compared to the remainder of the myocardium. During adenosine stress endocardial/epicardial ratio decrease significantly.
41 schema:genre research_article
42 schema:inLanguage en
43 schema:isAccessibleForFree false
44 schema:isPartOf N470c714d731748b18495426717b1812b
45 Nf86328c8f53b4cb6991cabe639e5dc30
46 sg:journal.1025429
47 schema:name Patterns of myocardial perfusion in humans evaluated with contrast-enhanced 320 multidetector computed tomography
48 schema:pagination 1739-1747
49 schema:productId N498e98d9c0c5400aa1a5a8ba50745e8d
50 N570704134786483e99ddf057f6a22c49
51 Nda2f1cd81cfd4907954c374e2df523e3
52 Nea96db3376ad41ab8f806537b39aef0b
53 Nf587d4fd16d14ca2bd9b850d19d30338
54 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050160560
55 https://doi.org/10.1007/s10554-011-9986-z
56 schema:sdDatePublished 2019-04-11T01:08
57 schema:sdLicense https://scigraph.springernature.com/explorer/license/
58 schema:sdPublisher Nd0ee26d0690f4fd3ac030ed2befadda6
59 schema:url http://link.springer.com/10.1007%2Fs10554-011-9986-z
60 sgo:license sg:explorer/license/
61 sgo:sdDataset articles
62 rdf:type schema:ScholarlyArticle
63 N14b615375abd4106a3f24b0f9638f546 schema:name Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark
64 Department of Radiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
65 rdf:type schema:Organization
66 N1c00c0833d5d4ec4a2ecc3b753e44b5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Reference Values
68 rdf:type schema:DefinedTerm
69 N1e096b2ec6434c9e9e0084b542c989e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Adenosine
71 rdf:type schema:DefinedTerm
72 N2ce738a17fb54d428565e1beed138bc6 rdf:first sg:person.01131014113.96
73 rdf:rest N2dd7cd8ba180452e9cc5c4dbd5a59d85
74 N2dd7cd8ba180452e9cc5c4dbd5a59d85 rdf:first sg:person.01150533044.15
75 rdf:rest N2edf8572a0784e1bb07a82add8d8fe08
76 N2edf8572a0784e1bb07a82add8d8fe08 rdf:first sg:person.0771034557.12
77 rdf:rest N5e74f87802e444a7b6b30532410a216d
78 N34e204d8598d4710b180c22467f6c5ca rdf:first sg:person.01136733117.88
79 rdf:rest N9726f5bd6b9848a1a226d694a4e1ad12
80 N3527163e744d4577a98b135693f49b2c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Coronary Circulation
82 rdf:type schema:DefinedTerm
83 N3b2b29dec6a9416fb014390df4bf71b2 schema:name Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark
84 rdf:type schema:Organization
85 N470c714d731748b18495426717b1812b schema:volumeNumber 28
86 rdf:type schema:PublicationVolume
87 N476361fcacae436095cfa7b680e2e859 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Analysis of Variance
89 rdf:type schema:DefinedTerm
90 N498e98d9c0c5400aa1a5a8ba50745e8d schema:name pubmed_id
91 schema:value 22143171
92 rdf:type schema:PropertyValue
93 N5209b736d9d74b0685ab0493d059d6aa schema:name Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark
94 rdf:type schema:Organization
95 N570704134786483e99ddf057f6a22c49 schema:name doi
96 schema:value 10.1007/s10554-011-9986-z
97 rdf:type schema:PropertyValue
98 N5e74f87802e444a7b6b30532410a216d rdf:first sg:person.01100661206.03
99 rdf:rest N34e204d8598d4710b180c22467f6c5ca
100 N64cf85c84db747c698804cfec1d0adb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Myocardial Perfusion Imaging
102 rdf:type schema:DefinedTerm
103 N72f6b5892f024d6597f825d30e0ce7aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Multidetector Computed Tomography
105 rdf:type schema:DefinedTerm
106 N9726f5bd6b9848a1a226d694a4e1ad12 rdf:first sg:person.016452166277.03
107 rdf:rest rdf:nil
108 N9f23394f4fb747b0964974db6bbb322d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Positron-Emission Tomography
110 rdf:type schema:DefinedTerm
111 Nb129e07951cd40d99a7bfbb691d6ea53 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Heart Ventricles
113 rdf:type schema:DefinedTerm
114 Nb4fd6f674af14d07b0a127177ed056f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Humans
116 rdf:type schema:DefinedTerm
117 Nd0ee26d0690f4fd3ac030ed2befadda6 schema:name Springer Nature - SN SciGraph project
118 rdf:type schema:Organization
119 Nd4bd583ca0254c10a86fe09e9af80c51 rdf:first sg:person.0706137677.23
120 rdf:rest N2ce738a17fb54d428565e1beed138bc6
121 Nd77d9640a2ff4362acdd6e4b1b7e2a12 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Vasodilator Agents
123 rdf:type schema:DefinedTerm
124 Nda2f1cd81cfd4907954c374e2df523e3 schema:name readcube_id
125 schema:value eef325ed474ffba08cbad79ccb1b879f11cf0973e7ae0e552588b8624f73d75a
126 rdf:type schema:PropertyValue
127 Ne5d7ea86a8584c30838a0c2af7d2c1e9 schema:name Department of Radiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
128 rdf:type schema:Organization
129 Ne5f0e967a4ba4c9591823d1fe9806034 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Predictive Value of Tests
131 rdf:type schema:DefinedTerm
132 Nea96db3376ad41ab8f806537b39aef0b schema:name nlm_unique_id
133 schema:value 100969716
134 rdf:type schema:PropertyValue
135 Neaaf249fed454073839abe2c21d11ac8 schema:name Department of Cardiology, 2012, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark
136 rdf:type schema:Organization
137 Nf587d4fd16d14ca2bd9b850d19d30338 schema:name dimensions_id
138 schema:value pub.1050160560
139 rdf:type schema:PropertyValue
140 Nf86328c8f53b4cb6991cabe639e5dc30 schema:issueNumber 7
141 rdf:type schema:PublicationIssue
142 Nfa7effe1152646b5a9b47ce8c57980ac rdf:first sg:person.01001370400.17
143 rdf:rest Nd4bd583ca0254c10a86fe09e9af80c51
144 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
145 schema:name Medical and Health Sciences
146 rdf:type schema:DefinedTerm
147 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
148 schema:name Clinical Sciences
149 rdf:type schema:DefinedTerm
150 sg:journal.1025429 schema:issn 1569-5794
151 1573-0743
152 schema:name The International Journal of Cardiovascular Imaging
153 rdf:type schema:Periodical
154 sg:person.01001370400.17 schema:affiliation Neaaf249fed454073839abe2c21d11ac8
155 schema:familyName Kühl
156 schema:givenName J. Tobias
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01001370400.17
158 rdf:type schema:Person
159 sg:person.01100661206.03 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
160 schema:familyName George
161 schema:givenName Richard T.
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100661206.03
163 rdf:type schema:Person
164 sg:person.01131014113.96 schema:affiliation N5209b736d9d74b0685ab0493d059d6aa
165 schema:familyName Fuchs
166 schema:givenName Andreas
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131014113.96
168 rdf:type schema:Person
169 sg:person.01136733117.88 schema:affiliation https://www.grid.ac/institutes/grid.5254.6
170 schema:familyName Hove
171 schema:givenName Jens D.
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136733117.88
173 rdf:type schema:Person
174 sg:person.01150533044.15 schema:affiliation Ne5d7ea86a8584c30838a0c2af7d2c1e9
175 schema:familyName Kristensen
176 schema:givenName Thomas S.
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150533044.15
178 rdf:type schema:Person
179 sg:person.016452166277.03 schema:affiliation N14b615375abd4106a3f24b0f9638f546
180 schema:familyName Kofoed
181 schema:givenName Klaus Fuglsang
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016452166277.03
183 rdf:type schema:Person
184 sg:person.0706137677.23 schema:affiliation https://www.grid.ac/institutes/grid.5254.6
185 schema:familyName Linde
186 schema:givenName Jesper J.
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706137677.23
188 rdf:type schema:Person
189 sg:person.0771034557.12 schema:affiliation N3b2b29dec6a9416fb014390df4bf71b2
190 schema:familyName Kelbæk
191 schema:givenName Henning
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771034557.12
193 rdf:type schema:Person
194 sg:pub.10.1007/s10554-009-9531-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036804512
195 https://doi.org/10.1007/s10554-009-9531-5
196 rdf:type schema:CreativeWork
197 sg:pub.10.1007/s12350-009-9156-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1021153314
198 https://doi.org/10.1007/s12350-009-9156-z
199 rdf:type schema:CreativeWork
200 sg:pub.10.1023/a:1011981526366 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026381728
201 https://doi.org/10.1023/a:1011981526366
202 rdf:type schema:CreativeWork
203 https://app.dimensions.ai/details/publication/pub.1076848166 schema:CreativeWork
204 https://app.dimensions.ai/details/publication/pub.1076848681 schema:CreativeWork
205 https://app.dimensions.ai/details/publication/pub.1082470357 schema:CreativeWork
206 https://doi.org/10.1002/mrm.22538 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045195610
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/j.jacc.2006.04.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033946852
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/j.jacc.2009.06.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028985969
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/s0735-1097(87)80083-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024102684
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1097/rli.0b013e318124a884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045237062
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1097/rli.0b013e3181c4f535 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010033371
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1097/rli.0b013e3181dfa2f2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036604988
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1148/radiol.09091014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010140910
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1148/radiol.10091399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040693172
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1148/radiol.2471070332 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030279036
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1152/ajpheart.1998.275.4.h1274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083319418
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1152/jappl.1992.73.6.2274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075678894
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1152/physrev.00045.2006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001000025
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1161/01.cir.17.3.391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053025551
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1161/01.cir.76.6.1262 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050887723
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1161/01.res.41.5.648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043537925
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1161/circimaging.108.813766 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035827179
239 rdf:type schema:CreativeWork
240 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
241 schema:name Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
242 rdf:type schema:Organization
243 https://www.grid.ac/institutes/grid.5254.6 schema:alternateName University of Copenhagen
244 schema:name Department of Cardiology, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark
245 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...