Gated blood pool SPECT for measurement of left ventricular volumes and left ventricular ejection fraction: comparison of 8 and 16 ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-04

AUTHORS

Seong-Jang Kim, In-Ju Kim, Yun-Seong Kim, Yong-Ki Kim

ABSTRACT

Gated blood pool SPECT (GBPS) is an alternative to planar radionuclide ventriculography (PRNV) and offers potential advantages. The aim of this study was to compare 8 and 16 frame GBPS for the determination of left ventricular ejection fraction(LVEF) and left ventricular volumes (LV) in subjects underwent two consecutive GBPS. Method: About 66 consecutive patients (30 men, 36 women; mean age 62.3 ± 10.4 years) referred for PRNV for evaluation of preoperative cardiac risk stratification (n=40), prechemotherapy cardiac function evaluation (n=18, breast cancer), and congestive heart failure patients (n=8). All patients underwent PRNV of 16 frame and GBPS with both of 8 and 16 frame. Results: The mean LVEF calculated with PRNV (58.3 ± 16.8), showed statistically lower than 8-GBPS (70.6 ± 17.7), and 16-GBPS (69.9 ± 16.8) (PRNV vs. 8-GBPS, p < 0.01; PRNV vs 16-GBPS, p < 0.01; 8-GBPS vs 16-GBPS, p > 0.05). The correlation of LVEFS between 8-GBPS and 16-GBPS showed a correlation coefficient of 0.9194 (p < 0.01, 95% CI=0.8712–0.9500). The mean left ventricular end-diastolic volumes (EDV) calculated with 8-GBPS (83.2 ± 33.5 ml), and 16-GBPS (88.4 ± 36.8 ml) showed no statistical differences (p > 0.05). The mean left ventricular end-systolic volumes (ESV) calculated with 8-GBPS (28.1 ± 31.4 ml), and 16-GBPS (30.5 ± 33 ml) showed also no statistical differences (p > 0.05). Comparison of EDV from 8 and 16-GBPS yielded a correlation coefficient of 0.7430 (p < 0.01, 95% CI=0.6108-0.8349). The correlation between ESV of 8-GBPS and 16-GBPS showed a correlation coefficient of 0.9522 (p < 0.01, 95% CI=0.9228–0.9705). Conclusion: This study demonstrated that the LVEFs of 8-GBPS correlated well with that of 16-GBPS. The LVEF of PRNV was significantly lower than those of 8 and 16-GBPS. Also, left ventricular EDV and ESV of 8-GBPS correlated well with those of 16-GBPS. Also, further studies, involving large lumber patients, should be performed to validate the usefulness of GBPS for the evaluation of left ventricular diastolic function. More... »

PAGES

261-266

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10554-004-6133-0

DOI

http://dx.doi.org/10.1007/s10554-004-6133-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009964032

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16015439


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