A family-based study of gene variants and maternal folate and choline in neuroblastoma: a report from the Children’s Oncology Group View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-10

AUTHORS

Angela L. Mazul, Anna Maria Siega-Riz, Clarice R. Weinberg, Stephanie M. Engel, Fei Zou, Kathryn S. Carrier, Patricia V. Basta, Zalman Vaksman, John M. Maris, Sharon J. Diskin, Charlene Maxen, Arlene Naranjo, Andrew F. Olshan

ABSTRACT

PURPOSE: Neuroblastoma is a childhood cancer of the sympathetic nervous system with embryonic origins. Previous epidemiologic studies suggest maternal vitamin supplementation during pregnancy reduces the risk of neuroblastoma. We hypothesized offspring and maternal genetic variants in folate-related and choline-related genes are associated with neuroblastoma and modify the effects of maternal intake of folate, choline, and folic acid. METHODS: The Neuroblastoma Epidemiology in North America (NENA) study recruited 563 affected children and their parents through the Children's Oncology Group's Childhood Cancer Research Network. We used questionnaires to ascertain pre-pregnancy supplementation and estimate usual maternal dietary intake of folate, choline, and folic acid. We genotyped 955 genetic variants related to folate or choline using DNA extracted from saliva samples and used a log-linear model to estimate both child and maternal risk ratios and stratum-specific risk ratios for gene-environment interactions. RESULTS: Overall, no maternal or offspring genotypic results met criteria for a false discovery rate (FDR) Q-value <0.2. Associations were also null for gene-environment interaction with pre-pregnancy vitamin supplementation, dietary folic acid, and folate. FDR-significant gene-choline interactions were found for offspring SNPs rs10489810 and rs9966612 located in MTHFD1L and TYMS, respectively, with maternal choline dietary intake dichotomized at the first quartile. CONCLUSION: These results suggest that variants related to one-carbon metabolism are not strongly associated with neuroblastoma. Choline-related variants may play a role; however, the functional consequences of the interacting variants are unknown and require independent replication. More... »

PAGES

1209-1218

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10552-016-0799-1

DOI

http://dx.doi.org/10.1007/s10552-016-0799-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005089459

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27541142


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Choline", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dietary Supplements", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Folic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene-Environment Interaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Variation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuroblastoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Odds Ratio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Registries", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "United States", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mazul", 
        "givenName": "Angela L.", 
        "id": "sg:person.0744770531.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744770531.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA", 
            "Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siega-Riz", 
        "givenName": "Anna Maria", 
        "id": "sg:person.0703761250.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703761250.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Environmental Health Sciences", 
          "id": "https://www.grid.ac/institutes/grid.280664.e", 
          "name": [
            "Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Weinberg", 
        "givenName": "Clarice R.", 
        "id": "sg:person.01005541755.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005541755.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Engel", 
        "givenName": "Stephanie M.", 
        "id": "sg:person.011374744077.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011374744077.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zou", 
        "givenName": "Fei", 
        "id": "sg:person.01034404673.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034404673.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Carrier", 
        "givenName": "Kathryn S.", 
        "id": "sg:person.01213517062.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213517062.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina System", 
          "id": "https://www.grid.ac/institutes/grid.410711.2", 
          "name": [
            "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA", 
            "Biospecimen Processing Center, University of North Carolina, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Basta", 
        "givenName": "Patricia V.", 
        "id": "sg:person.01363716002.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363716002.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Hospital of Philadelphia", 
          "id": "https://www.grid.ac/institutes/grid.239552.a", 
          "name": [
            "Division of Oncology and Center for Childhood Cancer Research, Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA", 
            "Department of Biomedical and Health Informatics, Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vaksman", 
        "givenName": "Zalman", 
        "id": "sg:person.01047255031.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047255031.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Pennsylvania", 
          "id": "https://www.grid.ac/institutes/grid.25879.31", 
          "name": [
            "Division of Oncology and Center for Childhood Cancer Research, Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA", 
            "Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maris", 
        "givenName": "John M.", 
        "id": "sg:person.0775660163.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775660163.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Pennsylvania", 
          "id": "https://www.grid.ac/institutes/grid.25879.31", 
          "name": [
            "Division of Oncology and Center for Childhood Cancer Research, Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA", 
            "Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Diskin", 
        "givenName": "Sharon J.", 
        "id": "sg:person.0635070737.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635070737.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Akron Children's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413473.6", 
          "name": [
            "Showers Center for Childhood Cancer and Blood Disorder, Akron Children\u2019s Hospital, Akron, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maxen", 
        "givenName": "Charlene", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Biostatistics, Colleges of Medicine and Public Health & Health Professions, University of Florida, Gainesville, FL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Naranjo", 
        "givenName": "Arlene", 
        "id": "sg:person.01157107214.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157107214.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of North Carolina at Chapel Hill", 
          "id": "https://www.grid.ac/institutes/grid.10698.36", 
          "name": [
            "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Olshan", 
        "givenName": "Andrew F.", 
        "id": "sg:person.012712323677.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012712323677.42"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1753-4887.2009.00246.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002446657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1753-4887.2009.00246.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002446657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/13816810600976871", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005667303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg2796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009739594", 
          "https://doi.org/10.1038/nrg2796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg2796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009739594", 
          "https://doi.org/10.1038/nrg2796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.23169", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010372207"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bdra.23005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011982583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014011076", 
          "https://doi.org/10.1038/nature08035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014011076", 
          "https://doi.org/10.1038/nature08035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.28813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016519757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3945/ajcn.2009.28401", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016847232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2006.05.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017813147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.aje.a008682", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018117566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/519795", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019061180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020230947", 
          "https://doi.org/10.1038/nature09609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pbc.23137", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020685359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1503/cmaj.081155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021176727"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1503/cmaj.081155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021176727"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/aje/kws303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021796568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.paed.2011.08.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022069187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3945/jn.115.211300", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024754327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025450596", 
          "https://doi.org/10.1038/ng.374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025450596", 
          "https://doi.org/10.1038/ng.374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/14767051003678234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026303173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btn564", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026900777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrdp.2016.79", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029964145", 
          "https://doi.org/10.1038/nrdp.2016.79"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.nutr.21.1.255", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033160204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/humu.21109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033783315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/humu.21109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033783315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/dvdy.10303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034280906"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra0804577", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034486634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3945/an.110.1010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035741113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1079/pns2001113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035942100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2350-13-77", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037311263", 
          "https://doi.org/10.1186/1471-2350-13-77"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bdra.20183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037718111"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bdra.20183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037718111"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajmg.a.35552", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038080805"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc3557", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038912868", 
          "https://doi.org/10.1038/nrc3557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btm426", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040245354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11033-014-3372-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043235344", 
          "https://doi.org/10.1007/s11033-014-3372-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.aje.a009715", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044902999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.2387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046277408", 
          "https://doi.org/10.1038/ng.2387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng2088", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046979341", 
          "https://doi.org/10.1038/ng2088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001648-200209000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053055862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001648-200209000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053055862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/301802", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058609408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/302337", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058609915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/302707", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058610273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/381000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058673096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/gtmb.2014.0177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059268259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1214/09-sts290", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064391121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/br.2013.134", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071502150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-150-9-200905050-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073710777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/71.5.1218s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074635876"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-10", 
    "datePublishedReg": "2016-10-01", 
    "description": "PURPOSE: Neuroblastoma is a childhood cancer of the sympathetic nervous system with embryonic origins. Previous epidemiologic studies suggest maternal vitamin supplementation during pregnancy reduces the risk of neuroblastoma. We hypothesized offspring and maternal genetic variants in folate-related and choline-related genes are associated with neuroblastoma and modify the effects of maternal intake of folate, choline, and folic acid.\nMETHODS: The Neuroblastoma Epidemiology in North America (NENA) study recruited 563 affected children and their parents through the Children's Oncology Group's Childhood Cancer Research Network. We used questionnaires to ascertain pre-pregnancy supplementation and estimate usual maternal dietary intake of folate, choline, and folic acid. We genotyped 955 genetic variants related to folate or choline using DNA extracted from saliva samples and used a log-linear model to estimate both child and maternal risk ratios and stratum-specific risk ratios for gene-environment interactions.\nRESULTS: Overall, no maternal or offspring genotypic results met criteria for a false discovery rate (FDR) Q-value\u00a0<0.2. Associations were also null for gene-environment interaction with pre-pregnancy vitamin supplementation, dietary folic acid, and folate. FDR-significant gene-choline interactions were found for offspring SNPs rs10489810 and rs9966612 located in MTHFD1L and TYMS, respectively, with maternal choline dietary intake dichotomized at the first quartile.\nCONCLUSION: These results suggest that variants related to one-carbon metabolism are not strongly associated with neuroblastoma. Choline-related variants may play a role; however, the functional consequences of the interacting variants are unknown and require independent replication.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10552-016-0799-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2439107", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2479060", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2622456", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3536120", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2479793", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6952720", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3535922", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.4455762", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1100917", 
        "issn": [
          "0957-5243", 
          "1573-7225"
        ], 
        "name": "Cancer Causes & Control", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "27"
      }
    ], 
    "name": "A family-based study of gene variants and maternal folate and choline in neuroblastoma: a report from the Children\u2019s Oncology Group", 
    "pagination": "1209-1218", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "183fbb7a9c038a3c7be2706fa5b35e18281b1a7db0efb068b3d527b60c625f1c"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27541142"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9100846"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10552-016-0799-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1005089459"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10552-016-0799-1", 
      "https://app.dimensions.ai/details/publication/pub.1005089459"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87094_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10552-016-0799-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10552-016-0799-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10552-016-0799-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10552-016-0799-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10552-016-0799-1'


 

This table displays all metadata directly associated to this object as RDF triples.

407 TRIPLES      21 PREDICATES      92 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10552-016-0799-1 schema:about N009b9a6e671943298623543e1ca99c06
2 N08d4ad97358947748aa0bd004fdaf443
3 N197cfe2d07ca498f92606d4f18941247
4 N2cc38b8dc51545439876c074851b9dde
5 N310831a63b8645f99ba1565e62f6afb7
6 N31193adf716d4e58af4b2c15b07640e9
7 N3c70b561ed714f40a6b93385da477eca
8 N3cda63e4d9434247846f9cb8d8625c24
9 N47f940d12f2745c98741d5e5b3e44fc3
10 N5a2c8b9ee7e64ae382e1a980e544ec47
11 N5cf321da26d849b694f073d9177975e5
12 N799a2e6962d943a7bdd706e7c411c9c7
13 N8bf85ce6af404a67b5297773d0c2a16f
14 Nb1abee12591b4caf8cf6f036da5be152
15 Nb72a055f5944400e97ad40857c7bc3ad
16 Nd33e42a64dec40d988e9dc19ff1c3206
17 Ne2f7134c88d144558becf34384cc89f1
18 anzsrc-for:11
19 anzsrc-for:1117
20 schema:author Ndc35352ba1114edbb0fb7f8c049986c5
21 schema:citation sg:pub.10.1007/s11033-014-3372-6
22 sg:pub.10.1038/nature08035
23 sg:pub.10.1038/nature09609
24 sg:pub.10.1038/ng.2387
25 sg:pub.10.1038/ng.374
26 sg:pub.10.1038/ng2088
27 sg:pub.10.1038/nrc3557
28 sg:pub.10.1038/nrdp.2016.79
29 sg:pub.10.1038/nrg2796
30 sg:pub.10.1186/1471-2350-13-77
31 https://doi.org/10.1002/ajmg.a.35552
32 https://doi.org/10.1002/bdra.20183
33 https://doi.org/10.1002/bdra.23005
34 https://doi.org/10.1002/cncr.23169
35 https://doi.org/10.1002/cncr.28813
36 https://doi.org/10.1002/dvdy.10303
37 https://doi.org/10.1002/humu.21109
38 https://doi.org/10.1002/pbc.23137
39 https://doi.org/10.1016/j.ejca.2006.05.008
40 https://doi.org/10.1016/j.paed.2011.08.005
41 https://doi.org/10.1056/nejmra0804577
42 https://doi.org/10.1079/pns2001113
43 https://doi.org/10.1080/13816810600976871
44 https://doi.org/10.1086/301802
45 https://doi.org/10.1086/302337
46 https://doi.org/10.1086/302707
47 https://doi.org/10.1086/381000
48 https://doi.org/10.1086/519795
49 https://doi.org/10.1089/gtmb.2014.0177
50 https://doi.org/10.1093/ajcn/71.5.1218s
51 https://doi.org/10.1093/aje/kws303
52 https://doi.org/10.1093/bioinformatics/btm426
53 https://doi.org/10.1093/bioinformatics/btn564
54 https://doi.org/10.1093/oxfordjournals.aje.a008682
55 https://doi.org/10.1093/oxfordjournals.aje.a009715
56 https://doi.org/10.1097/00001648-200209000-00014
57 https://doi.org/10.1111/j.1753-4887.2009.00246.x
58 https://doi.org/10.1146/annurev.nutr.21.1.255
59 https://doi.org/10.1214/09-sts290
60 https://doi.org/10.1503/cmaj.081155
61 https://doi.org/10.3109/14767051003678234
62 https://doi.org/10.3892/br.2013.134
63 https://doi.org/10.3945/ajcn.2009.28401
64 https://doi.org/10.3945/an.110.1010
65 https://doi.org/10.3945/jn.115.211300
66 https://doi.org/10.7326/0003-4819-150-9-200905050-00009
67 schema:datePublished 2016-10
68 schema:datePublishedReg 2016-10-01
69 schema:description PURPOSE: Neuroblastoma is a childhood cancer of the sympathetic nervous system with embryonic origins. Previous epidemiologic studies suggest maternal vitamin supplementation during pregnancy reduces the risk of neuroblastoma. We hypothesized offspring and maternal genetic variants in folate-related and choline-related genes are associated with neuroblastoma and modify the effects of maternal intake of folate, choline, and folic acid. METHODS: The Neuroblastoma Epidemiology in North America (NENA) study recruited 563 affected children and their parents through the Children's Oncology Group's Childhood Cancer Research Network. We used questionnaires to ascertain pre-pregnancy supplementation and estimate usual maternal dietary intake of folate, choline, and folic acid. We genotyped 955 genetic variants related to folate or choline using DNA extracted from saliva samples and used a log-linear model to estimate both child and maternal risk ratios and stratum-specific risk ratios for gene-environment interactions. RESULTS: Overall, no maternal or offspring genotypic results met criteria for a false discovery rate (FDR) Q-value <0.2. Associations were also null for gene-environment interaction with pre-pregnancy vitamin supplementation, dietary folic acid, and folate. FDR-significant gene-choline interactions were found for offspring SNPs rs10489810 and rs9966612 located in MTHFD1L and TYMS, respectively, with maternal choline dietary intake dichotomized at the first quartile. CONCLUSION: These results suggest that variants related to one-carbon metabolism are not strongly associated with neuroblastoma. Choline-related variants may play a role; however, the functional consequences of the interacting variants are unknown and require independent replication.
70 schema:genre research_article
71 schema:inLanguage en
72 schema:isAccessibleForFree true
73 schema:isPartOf N497ba78e73424bc0b3331b01f1bbab0d
74 N5a1a40ba0b594dfcb82594465897c2a6
75 sg:journal.1100917
76 schema:name A family-based study of gene variants and maternal folate and choline in neuroblastoma: a report from the Children’s Oncology Group
77 schema:pagination 1209-1218
78 schema:productId N0d54e3271329486baf0dde252cf9092c
79 N918377cac84a4338a82b97f040757578
80 Nc24f1fd1718648d995feff3dea80c80c
81 Nd3695ab01a4d4f2dbca213a84e2c6768
82 Ndc2c96a8ab4e42238fa804a67db6eb99
83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005089459
84 https://doi.org/10.1007/s10552-016-0799-1
85 schema:sdDatePublished 2019-04-11T12:23
86 schema:sdLicense https://scigraph.springernature.com/explorer/license/
87 schema:sdPublisher N4e657ac17db04943b60ca71b84b828b3
88 schema:url https://link.springer.com/10.1007%2Fs10552-016-0799-1
89 sgo:license sg:explorer/license/
90 sgo:sdDataset articles
91 rdf:type schema:ScholarlyArticle
92 N009b9a6e671943298623543e1ca99c06 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Dietary Supplements
94 rdf:type schema:DefinedTerm
95 N08d4ad97358947748aa0bd004fdaf443 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Pregnancy
97 rdf:type schema:DefinedTerm
98 N0d54e3271329486baf0dde252cf9092c schema:name readcube_id
99 schema:value 183fbb7a9c038a3c7be2706fa5b35e18281b1a7db0efb068b3d527b60c625f1c
100 rdf:type schema:PropertyValue
101 N126e21a43954409f81e86d77c7385991 rdf:first sg:person.0703761250.01
102 rdf:rest Na8f3f8706d7a415aa3a350467e77c4df
103 N197cfe2d07ca498f92606d4f18941247 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Genotype
105 rdf:type schema:DefinedTerm
106 N29a1b5dfec2248339aed88fd5c727ec0 rdf:first sg:person.01213517062.04
107 rdf:rest N7ac4d30c92344f11b189bc7fe8e5c29c
108 N2cc38b8dc51545439876c074851b9dde schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Male
110 rdf:type schema:DefinedTerm
111 N310831a63b8645f99ba1565e62f6afb7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Choline
113 rdf:type schema:DefinedTerm
114 N31193adf716d4e58af4b2c15b07640e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Odds Ratio
116 rdf:type schema:DefinedTerm
117 N3a2e9ba8028e42eb9f7daee923b3eced rdf:first sg:person.0775660163.63
118 rdf:rest N772dda96ea0149889d5af6481c266817
119 N3c70b561ed714f40a6b93385da477eca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Humans
121 rdf:type schema:DefinedTerm
122 N3cda63e4d9434247846f9cb8d8625c24 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Registries
124 rdf:type schema:DefinedTerm
125 N3da32fa4effe488a82b4c36984860a01 rdf:first sg:person.01034404673.62
126 rdf:rest N29a1b5dfec2248339aed88fd5c727ec0
127 N47f940d12f2745c98741d5e5b3e44fc3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Gene-Environment Interaction
129 rdf:type schema:DefinedTerm
130 N497ba78e73424bc0b3331b01f1bbab0d schema:issueNumber 10
131 rdf:type schema:PublicationIssue
132 N4e657ac17db04943b60ca71b84b828b3 schema:name Springer Nature - SN SciGraph project
133 rdf:type schema:Organization
134 N537ce5d1fa4a4b92a91ef0d8b9bcaae7 rdf:first sg:person.01047255031.50
135 rdf:rest N3a2e9ba8028e42eb9f7daee923b3eced
136 N5a1a40ba0b594dfcb82594465897c2a6 schema:volumeNumber 27
137 rdf:type schema:PublicationVolume
138 N5a2c8b9ee7e64ae382e1a980e544ec47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Neuroblastoma
140 rdf:type schema:DefinedTerm
141 N5cf321da26d849b694f073d9177975e5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Child, Preschool
143 rdf:type schema:DefinedTerm
144 N66c04092315842d28ab4f3ce5062f148 schema:affiliation https://www.grid.ac/institutes/grid.413473.6
145 schema:familyName Maxen
146 schema:givenName Charlene
147 rdf:type schema:Person
148 N772dda96ea0149889d5af6481c266817 rdf:first sg:person.0635070737.26
149 rdf:rest Nbd148e1480644d08bd7aa97c0fb6dd09
150 N799a2e6962d943a7bdd706e7c411c9c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Infant
152 rdf:type schema:DefinedTerm
153 N7ac4d30c92344f11b189bc7fe8e5c29c rdf:first sg:person.01363716002.06
154 rdf:rest N537ce5d1fa4a4b92a91ef0d8b9bcaae7
155 N8bf85ce6af404a67b5297773d0c2a16f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Polymorphism, Single Nucleotide
157 rdf:type schema:DefinedTerm
158 N918377cac84a4338a82b97f040757578 schema:name dimensions_id
159 schema:value pub.1005089459
160 rdf:type schema:PropertyValue
161 Na8f3f8706d7a415aa3a350467e77c4df rdf:first sg:person.01005541755.78
162 rdf:rest Nc2395b45ee2f421aa8f354ba0af60c93
163 Nb1abee12591b4caf8cf6f036da5be152 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name United States
165 rdf:type schema:DefinedTerm
166 Nb72a055f5944400e97ad40857c7bc3ad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Genetic Variation
168 rdf:type schema:DefinedTerm
169 Nbd148e1480644d08bd7aa97c0fb6dd09 rdf:first N66c04092315842d28ab4f3ce5062f148
170 rdf:rest Nef43cff9b2554ee9bf9fe38f008d78d9
171 Nc2395b45ee2f421aa8f354ba0af60c93 rdf:first sg:person.011374744077.86
172 rdf:rest N3da32fa4effe488a82b4c36984860a01
173 Nc24f1fd1718648d995feff3dea80c80c schema:name doi
174 schema:value 10.1007/s10552-016-0799-1
175 rdf:type schema:PropertyValue
176 Nd33e42a64dec40d988e9dc19ff1c3206 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Folic Acid
178 rdf:type schema:DefinedTerm
179 Nd3695ab01a4d4f2dbca213a84e2c6768 schema:name nlm_unique_id
180 schema:value 9100846
181 rdf:type schema:PropertyValue
182 Ndc2c96a8ab4e42238fa804a67db6eb99 schema:name pubmed_id
183 schema:value 27541142
184 rdf:type schema:PropertyValue
185 Ndc35352ba1114edbb0fb7f8c049986c5 rdf:first sg:person.0744770531.07
186 rdf:rest N126e21a43954409f81e86d77c7385991
187 Ne00367a4795942f5a10e226e7e86c982 rdf:first sg:person.012712323677.42
188 rdf:rest rdf:nil
189 Ne2f7134c88d144558becf34384cc89f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Female
191 rdf:type schema:DefinedTerm
192 Nef43cff9b2554ee9bf9fe38f008d78d9 rdf:first sg:person.01157107214.98
193 rdf:rest Ne00367a4795942f5a10e226e7e86c982
194 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
195 schema:name Medical and Health Sciences
196 rdf:type schema:DefinedTerm
197 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
198 schema:name Public Health and Health Services
199 rdf:type schema:DefinedTerm
200 sg:grant.2439107 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
201 rdf:type schema:MonetaryGrant
202 sg:grant.2479060 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
203 rdf:type schema:MonetaryGrant
204 sg:grant.2479793 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
205 rdf:type schema:MonetaryGrant
206 sg:grant.2622456 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
207 rdf:type schema:MonetaryGrant
208 sg:grant.3535922 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
209 rdf:type schema:MonetaryGrant
210 sg:grant.3536120 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
211 rdf:type schema:MonetaryGrant
212 sg:grant.4455762 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
213 rdf:type schema:MonetaryGrant
214 sg:grant.6952720 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-016-0799-1
215 rdf:type schema:MonetaryGrant
216 sg:journal.1100917 schema:issn 0957-5243
217 1573-7225
218 schema:name Cancer Causes & Control
219 rdf:type schema:Periodical
220 sg:person.01005541755.78 schema:affiliation https://www.grid.ac/institutes/grid.280664.e
221 schema:familyName Weinberg
222 schema:givenName Clarice R.
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005541755.78
224 rdf:type schema:Person
225 sg:person.01034404673.62 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
226 schema:familyName Zou
227 schema:givenName Fei
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034404673.62
229 rdf:type schema:Person
230 sg:person.01047255031.50 schema:affiliation https://www.grid.ac/institutes/grid.239552.a
231 schema:familyName Vaksman
232 schema:givenName Zalman
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047255031.50
234 rdf:type schema:Person
235 sg:person.011374744077.86 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
236 schema:familyName Engel
237 schema:givenName Stephanie M.
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011374744077.86
239 rdf:type schema:Person
240 sg:person.01157107214.98 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
241 schema:familyName Naranjo
242 schema:givenName Arlene
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157107214.98
244 rdf:type schema:Person
245 sg:person.01213517062.04 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
246 schema:familyName Carrier
247 schema:givenName Kathryn S.
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213517062.04
249 rdf:type schema:Person
250 sg:person.012712323677.42 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
251 schema:familyName Olshan
252 schema:givenName Andrew F.
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012712323677.42
254 rdf:type schema:Person
255 sg:person.01363716002.06 schema:affiliation https://www.grid.ac/institutes/grid.410711.2
256 schema:familyName Basta
257 schema:givenName Patricia V.
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363716002.06
259 rdf:type schema:Person
260 sg:person.0635070737.26 schema:affiliation https://www.grid.ac/institutes/grid.25879.31
261 schema:familyName Diskin
262 schema:givenName Sharon J.
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635070737.26
264 rdf:type schema:Person
265 sg:person.0703761250.01 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
266 schema:familyName Siega-Riz
267 schema:givenName Anna Maria
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703761250.01
269 rdf:type schema:Person
270 sg:person.0744770531.07 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
271 schema:familyName Mazul
272 schema:givenName Angela L.
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744770531.07
274 rdf:type schema:Person
275 sg:person.0775660163.63 schema:affiliation https://www.grid.ac/institutes/grid.25879.31
276 schema:familyName Maris
277 schema:givenName John M.
278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775660163.63
279 rdf:type schema:Person
280 sg:pub.10.1007/s11033-014-3372-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043235344
281 https://doi.org/10.1007/s11033-014-3372-6
282 rdf:type schema:CreativeWork
283 sg:pub.10.1038/nature08035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014011076
284 https://doi.org/10.1038/nature08035
285 rdf:type schema:CreativeWork
286 sg:pub.10.1038/nature09609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020230947
287 https://doi.org/10.1038/nature09609
288 rdf:type schema:CreativeWork
289 sg:pub.10.1038/ng.2387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046277408
290 https://doi.org/10.1038/ng.2387
291 rdf:type schema:CreativeWork
292 sg:pub.10.1038/ng.374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025450596
293 https://doi.org/10.1038/ng.374
294 rdf:type schema:CreativeWork
295 sg:pub.10.1038/ng2088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046979341
296 https://doi.org/10.1038/ng2088
297 rdf:type schema:CreativeWork
298 sg:pub.10.1038/nrc3557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038912868
299 https://doi.org/10.1038/nrc3557
300 rdf:type schema:CreativeWork
301 sg:pub.10.1038/nrdp.2016.79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029964145
302 https://doi.org/10.1038/nrdp.2016.79
303 rdf:type schema:CreativeWork
304 sg:pub.10.1038/nrg2796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009739594
305 https://doi.org/10.1038/nrg2796
306 rdf:type schema:CreativeWork
307 sg:pub.10.1186/1471-2350-13-77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037311263
308 https://doi.org/10.1186/1471-2350-13-77
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1002/ajmg.a.35552 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038080805
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1002/bdra.20183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037718111
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1002/bdra.23005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011982583
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1002/cncr.23169 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010372207
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1002/cncr.28813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016519757
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1002/dvdy.10303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034280906
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1002/humu.21109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033783315
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1002/pbc.23137 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020685359
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1016/j.ejca.2006.05.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017813147
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/j.paed.2011.08.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022069187
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1056/nejmra0804577 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034486634
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1079/pns2001113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035942100
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1080/13816810600976871 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005667303
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1086/301802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058609408
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1086/302337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058609915
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1086/302707 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058610273
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1086/381000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058673096
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1086/519795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019061180
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1089/gtmb.2014.0177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059268259
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1093/ajcn/71.5.1218s schema:sameAs https://app.dimensions.ai/details/publication/pub.1074635876
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1093/aje/kws303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021796568
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1093/bioinformatics/btm426 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040245354
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1093/bioinformatics/btn564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026900777
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1093/oxfordjournals.aje.a008682 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018117566
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1093/oxfordjournals.aje.a009715 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044902999
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1097/00001648-200209000-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053055862
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1111/j.1753-4887.2009.00246.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002446657
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1146/annurev.nutr.21.1.255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033160204
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1214/09-sts290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064391121
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1503/cmaj.081155 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021176727
369 rdf:type schema:CreativeWork
370 https://doi.org/10.3109/14767051003678234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026303173
371 rdf:type schema:CreativeWork
372 https://doi.org/10.3892/br.2013.134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071502150
373 rdf:type schema:CreativeWork
374 https://doi.org/10.3945/ajcn.2009.28401 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016847232
375 rdf:type schema:CreativeWork
376 https://doi.org/10.3945/an.110.1010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035741113
377 rdf:type schema:CreativeWork
378 https://doi.org/10.3945/jn.115.211300 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024754327
379 rdf:type schema:CreativeWork
380 https://doi.org/10.7326/0003-4819-150-9-200905050-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073710777
381 rdf:type schema:CreativeWork
382 https://www.grid.ac/institutes/grid.10698.36 schema:alternateName University of North Carolina at Chapel Hill
383 schema:name Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA
384 Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA
385 Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA
386 rdf:type schema:Organization
387 https://www.grid.ac/institutes/grid.15276.37 schema:alternateName University of Florida
388 schema:name Department of Biostatistics, Colleges of Medicine and Public Health & Health Professions, University of Florida, Gainesville, FL, USA
389 rdf:type schema:Organization
390 https://www.grid.ac/institutes/grid.239552.a schema:alternateName Children's Hospital of Philadelphia
391 schema:name Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
392 Division of Oncology and Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
393 rdf:type schema:Organization
394 https://www.grid.ac/institutes/grid.25879.31 schema:alternateName University of Pennsylvania
395 schema:name Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
396 Division of Oncology and Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
397 rdf:type schema:Organization
398 https://www.grid.ac/institutes/grid.280664.e schema:alternateName National Institute of Environmental Health Sciences
399 schema:name Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
400 rdf:type schema:Organization
401 https://www.grid.ac/institutes/grid.410711.2 schema:alternateName University of North Carolina System
402 schema:name Biospecimen Processing Center, University of North Carolina, Chapel Hill, NC, USA
403 Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, 27599-7435, Chapel Hill, NC, USA
404 rdf:type schema:Organization
405 https://www.grid.ac/institutes/grid.413473.6 schema:alternateName Akron Children's Hospital
406 schema:name Showers Center for Childhood Cancer and Blood Disorder, Akron Children’s Hospital, Akron, OH, USA
407 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...