Association of secondhand smoke exposures with DNA methylation in bladder carcinomas View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-08

AUTHORS

Charlotte S. Wilhelm-Benartzi, Brock C. Christensen, Devin C. Koestler, E. Andres Houseman, Alan R. Schned, Margaret R. Karagas, Karl T. Kelsey, Carmen J. Marsit

ABSTRACT

BACKGROUND: The association between secondhand smoke (SHS) exposure and bladder cancer is inconclusive. Epigenetic alterations in bladder tumors have been linked to primary cigarette smoking and could add to the biological plausibility of an association between SHS exposure and bladder cancer. HYPOTHESIS: SHS exposure is associated with DNA methylation in bladder tumors. METHODS: Using an array-based approach, we profiled DNA methylation from never smoking cases of incident bladder cancer. Analyses examined associations between individual loci's methylation with SHS variables (exposure in adulthood, childhood, occupationally, and total exposure). A canonical pathway analysis was used to find pathways significantly associated with each SHS exposure type. RESULTS: There is a trend toward increased methylation of numerous CpG loci with increasing exposure to adulthood, occupational, and total SHS. Discrete associations between methylation extent of several CpG loci and SHS exposures demonstrated significantly increased methylation of these loci across all types of SHS exposure. CpGs with SHS-related methylation alterations were associated with genes in pathways involved in carcinogenesis, immune modulation, and immune signaling. INTERPRETATION: Exposures to SHS in adulthood, childhood, occupationally, and in total are each significantly associated with changes in DNA methylation of several CpG loci in bladder tumors, adding biological plausibility to SHS as a risk factor for bladder cancer. More... »

PAGES

1205-1213

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10552-011-9788-6

DOI

http://dx.doi.org/10.1007/s10552-011-9788-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008764704

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21660454


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Methylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Environmental Exposure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Smoke", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tobacco Smoke Pollution", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urinary Bladder Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Brown University", 
          "id": "https://www.grid.ac/institutes/grid.40263.33", 
          "name": [
            "Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wilhelm-Benartzi", 
        "givenName": "Charlotte S.", 
        "id": "sg:person.01226701141.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226701141.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brown University", 
          "id": "https://www.grid.ac/institutes/grid.40263.33", 
          "name": [
            "Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA", 
            "Department of Pathology and Laboratory Medicine, Brown University, Box G-E537, 02912, Providence, RI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Christensen", 
        "givenName": "Brock C.", 
        "id": "sg:person.01100506032.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100506032.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brown University", 
          "id": "https://www.grid.ac/institutes/grid.40263.33", 
          "name": [
            "Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koestler", 
        "givenName": "Devin C.", 
        "id": "sg:person.0665636641.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665636641.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brown University", 
          "id": "https://www.grid.ac/institutes/grid.40263.33", 
          "name": [
            "Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Andres Houseman", 
        "givenName": "E.", 
        "id": "sg:person.01170010143.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170010143.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dartmouth College", 
          "id": "https://www.grid.ac/institutes/grid.254880.3", 
          "name": [
            "Department of Pathology, Dartmouth Medical School, Lebanon, NH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schned", 
        "givenName": "Alan R.", 
        "id": "sg:person.01077706721.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077706721.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dartmouth College", 
          "id": "https://www.grid.ac/institutes/grid.254880.3", 
          "name": [
            "Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Karagas", 
        "givenName": "Margaret R.", 
        "id": "sg:person.07573167157.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07573167157.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brown University", 
          "id": "https://www.grid.ac/institutes/grid.40263.33", 
          "name": [
            "Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA", 
            "Department of Pathology and Laboratory Medicine, Brown University, Box G-E537, 02912, Providence, RI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kelsey", 
        "givenName": "Karl T.", 
        "id": "sg:person.0603341031.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603341031.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brown University", 
          "id": "https://www.grid.ac/institutes/grid.40263.33", 
          "name": [
            "Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA", 
            "Department of Pathology and Laboratory Medicine, Brown University, Box G-E537, 02912, Providence, RI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Marsit", 
        "givenName": "Carmen J.", 
        "id": "sg:person.01065166305.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065166305.40"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1371/journal.pgen.1001043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001869456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0371254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004867967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0371254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004867967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-05-2580", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005441037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2009-05-222208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007002501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1467-9868.2004.00439.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007395272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/03008880802285032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007941239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yexcr.2010.03.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008506367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.2910440411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010898321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/b:caco.0000036452.55199.a3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011609224", 
          "https://doi.org/10.1023/b:caco.0000036452.55199.a3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2004.08.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012235373"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)60491-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017197399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1013954932343", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018978333", 
          "https://doi.org/10.1023/a:1013954932343"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-3835(87)90079-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019918293"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1071545", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021511972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mrgentox.2006.02.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022709676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-05-0267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026512316"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/93.5.378", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026600565"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199905063401810", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027579263"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa043331", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029207836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.4410706", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033075033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/carcin/bgi172", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037478026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1055-9965.epi-06-0636", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038301216"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/carcin/bgm116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038496205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkj468", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038984084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0012334", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039236324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lfs.2010.05.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040946679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041169608", 
          "https://doi.org/10.1038/nrc1799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041169608", 
          "https://doi.org/10.1038/nrc1799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-06-4567", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044178352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jat/30.3.187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044989538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncpuro0318", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045623818", 
          "https://doi.org/10.1038/ncpuro0318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncpuro0318", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045623818", 
          "https://doi.org/10.1038/ncpuro0318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molmed.2009.12.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047503737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.11467", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047900870"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ni1558", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049440431", 
          "https://doi.org/10.1038/ni1558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0008357", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050617185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/djp361", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051754382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1018453104303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052300916", 
          "https://doi.org/10.1023/a:1018453104303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcp.22209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053287283"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcp.22209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053287283"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg816", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053491434", 
          "https://doi.org/10.1038/nrg816"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg816", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053491434", 
          "https://doi.org/10.1038/nrg816"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(86)90360-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054549956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1081/gnc-120021372", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058431294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1289/ehp.98106s41047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064747148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/156652408785747979", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069185942"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/ijmm.14.5.825", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071505862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075303191", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077285953", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.aje.a113980", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080057177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/acprof:oso/9780195149616.003.0058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1088889222"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-08", 
    "datePublishedReg": "2011-08-01", 
    "description": "BACKGROUND: The association between secondhand smoke (SHS) exposure and bladder cancer is inconclusive. Epigenetic alterations in bladder tumors have been linked to primary cigarette smoking and could add to the biological plausibility of an association between SHS exposure and bladder cancer.\nHYPOTHESIS: SHS exposure is associated with DNA methylation in bladder tumors.\nMETHODS: Using an array-based approach, we profiled DNA methylation from never smoking cases of incident bladder cancer. Analyses examined associations between individual loci's methylation with SHS variables (exposure in adulthood, childhood, occupationally, and total exposure). A canonical pathway analysis was used to find pathways significantly associated with each SHS exposure type.\nRESULTS: There is a trend toward increased methylation of numerous CpG loci with increasing exposure to adulthood, occupational, and total SHS. Discrete associations between methylation extent of several CpG loci and SHS exposures demonstrated significantly increased methylation of these loci across all types of SHS exposure. CpGs with SHS-related methylation alterations were associated with genes in pathways involved in carcinogenesis, immune modulation, and immune signaling.\nINTERPRETATION: Exposures to SHS in adulthood, childhood, occupationally, and in total are each significantly associated with changes in DNA methylation of several CpG loci in bladder tumors, adding biological plausibility to SHS as a risk factor for bladder cancer.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10552-011-9788-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2439959", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2438839", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2478773", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2471226", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1100917", 
        "issn": [
          "0957-5243", 
          "1573-7225"
        ], 
        "name": "Cancer Causes & Control", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "22"
      }
    ], 
    "name": "Association of secondhand smoke exposures with DNA methylation in bladder carcinomas", 
    "pagination": "1205-1213", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "29c201b2751de8bc912d44fe34e604c0b19769f9a34b0fa03a2902752a5de275"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21660454"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9100846"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10552-011-9788-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1008764704"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10552-011-9788-6", 
      "https://app.dimensions.ai/details/publication/pub.1008764704"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000480.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s10552-011-9788-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10552-011-9788-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10552-011-9788-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10552-011-9788-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10552-011-9788-6'


 

This table displays all metadata directly associated to this object as RDF triples.

313 TRIPLES      21 PREDICATES      85 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10552-011-9788-6 schema:about N09b5953327934986be1886d01f400454
2 N4a5d809df1d44b458103d1b23dca54b1
3 N81ffa62a017d4ff181847080ec2523c2
4 N8df59c6d19684c8b805f049513229a45
5 N928d705383194681886ab09d0b55722c
6 Na95c1056750a405389873980a4b1ec3d
7 Nbd6da72294e34c6db53120729804dce1
8 Nd9ede3f576f442ffb36845a7eaf3846a
9 Nea5d8532263046ed898a4c4d839a598e
10 anzsrc-for:11
11 anzsrc-for:1117
12 schema:author Nd2e3183978984e0db395aeddad8a4d65
13 schema:citation sg:pub.10.1023/a:1013954932343
14 sg:pub.10.1023/a:1018453104303
15 sg:pub.10.1023/b:caco.0000036452.55199.a3
16 sg:pub.10.1038/ncpuro0318
17 sg:pub.10.1038/ni1558
18 sg:pub.10.1038/nrc1799
19 sg:pub.10.1038/nrg816
20 https://app.dimensions.ai/details/publication/pub.1075303191
21 https://app.dimensions.ai/details/publication/pub.1077285953
22 https://doi.org/10.1002/ijc.11467
23 https://doi.org/10.1002/ijc.2910440411
24 https://doi.org/10.1002/jcp.22209
25 https://doi.org/10.1016/0092-8674(86)90360-0
26 https://doi.org/10.1016/0304-3835(87)90079-6
27 https://doi.org/10.1016/j.ccr.2004.08.002
28 https://doi.org/10.1016/j.lfs.2010.05.001
29 https://doi.org/10.1016/j.molmed.2009.12.004
30 https://doi.org/10.1016/j.mrgentox.2006.02.015
31 https://doi.org/10.1016/j.yexcr.2010.03.007
32 https://doi.org/10.1016/s0140-6736(09)60491-8
33 https://doi.org/10.1042/bst0371254
34 https://doi.org/10.1056/nejm199905063401810
35 https://doi.org/10.1056/nejmoa043331
36 https://doi.org/10.1080/03008880802285032
37 https://doi.org/10.1081/gnc-120021372
38 https://doi.org/10.1093/acprof:oso/9780195149616.003.0058
39 https://doi.org/10.1093/carcin/bgi172
40 https://doi.org/10.1093/carcin/bgm116
41 https://doi.org/10.1093/jat/30.3.187
42 https://doi.org/10.1093/jnci/93.5.378
43 https://doi.org/10.1093/jnci/djp361
44 https://doi.org/10.1093/nar/gkj468
45 https://doi.org/10.1093/oxfordjournals.aje.a113980
46 https://doi.org/10.1101/gr.4410706
47 https://doi.org/10.1111/j.1467-9868.2004.00439.x
48 https://doi.org/10.1126/science.1071545
49 https://doi.org/10.1158/0008-5472.can-05-0267
50 https://doi.org/10.1158/0008-5472.can-05-2580
51 https://doi.org/10.1158/0008-5472.can-06-4567
52 https://doi.org/10.1158/1055-9965.epi-06-0636
53 https://doi.org/10.1182/blood-2009-05-222208
54 https://doi.org/10.1289/ehp.98106s41047
55 https://doi.org/10.1371/journal.pgen.1001043
56 https://doi.org/10.1371/journal.pone.0008357
57 https://doi.org/10.1371/journal.pone.0012334
58 https://doi.org/10.2174/156652408785747979
59 https://doi.org/10.3892/ijmm.14.5.825
60 schema:datePublished 2011-08
61 schema:datePublishedReg 2011-08-01
62 schema:description BACKGROUND: The association between secondhand smoke (SHS) exposure and bladder cancer is inconclusive. Epigenetic alterations in bladder tumors have been linked to primary cigarette smoking and could add to the biological plausibility of an association between SHS exposure and bladder cancer. HYPOTHESIS: SHS exposure is associated with DNA methylation in bladder tumors. METHODS: Using an array-based approach, we profiled DNA methylation from never smoking cases of incident bladder cancer. Analyses examined associations between individual loci's methylation with SHS variables (exposure in adulthood, childhood, occupationally, and total exposure). A canonical pathway analysis was used to find pathways significantly associated with each SHS exposure type. RESULTS: There is a trend toward increased methylation of numerous CpG loci with increasing exposure to adulthood, occupational, and total SHS. Discrete associations between methylation extent of several CpG loci and SHS exposures demonstrated significantly increased methylation of these loci across all types of SHS exposure. CpGs with SHS-related methylation alterations were associated with genes in pathways involved in carcinogenesis, immune modulation, and immune signaling. INTERPRETATION: Exposures to SHS in adulthood, childhood, occupationally, and in total are each significantly associated with changes in DNA methylation of several CpG loci in bladder tumors, adding biological plausibility to SHS as a risk factor for bladder cancer.
63 schema:genre research_article
64 schema:inLanguage en
65 schema:isAccessibleForFree true
66 schema:isPartOf N1ea10c8ea7f745ca867a22c948763f85
67 N59b83ec41cba41e8bab92ff59bccbbcf
68 sg:journal.1100917
69 schema:name Association of secondhand smoke exposures with DNA methylation in bladder carcinomas
70 schema:pagination 1205-1213
71 schema:productId N13a9b3afe00b46b3ad5ae1fb3733e32f
72 N24c5b66753c54033b090210bf10abadc
73 N732a2c1d143d4ba3827dd801f43ccb99
74 N8353f0a200d148afaef2dbc42b564598
75 Ndedaaabcc1204fdfa09e7fa7109bff33
76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008764704
77 https://doi.org/10.1007/s10552-011-9788-6
78 schema:sdDatePublished 2019-04-11T01:00
79 schema:sdLicense https://scigraph.springernature.com/explorer/license/
80 schema:sdPublisher Neefe1c1451f64d848fbb2625a99f8d2b
81 schema:url http://link.springer.com/10.1007/s10552-011-9788-6
82 sgo:license sg:explorer/license/
83 sgo:sdDataset articles
84 rdf:type schema:ScholarlyArticle
85 N09b5953327934986be1886d01f400454 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Humans
87 rdf:type schema:DefinedTerm
88 N13a9b3afe00b46b3ad5ae1fb3733e32f schema:name readcube_id
89 schema:value 29c201b2751de8bc912d44fe34e604c0b19769f9a34b0fa03a2902752a5de275
90 rdf:type schema:PropertyValue
91 N1ea10c8ea7f745ca867a22c948763f85 schema:volumeNumber 22
92 rdf:type schema:PublicationVolume
93 N1fc3798523494f23a1bbcb273d7c8914 rdf:first sg:person.07573167157.40
94 rdf:rest Nfe6cda88ff074791b52ede5c6e09e975
95 N24c5b66753c54033b090210bf10abadc schema:name doi
96 schema:value 10.1007/s10552-011-9788-6
97 rdf:type schema:PropertyValue
98 N3a4c7c4bd9b04be4ba3ecd03fc10ada2 rdf:first sg:person.01170010143.70
99 rdf:rest Nc59e75352d4a4f88b79238e758f69f66
100 N4a5d809df1d44b458103d1b23dca54b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Urinary Bladder Neoplasms
102 rdf:type schema:DefinedTerm
103 N59b83ec41cba41e8bab92ff59bccbbcf schema:issueNumber 8
104 rdf:type schema:PublicationIssue
105 N732a2c1d143d4ba3827dd801f43ccb99 schema:name nlm_unique_id
106 schema:value 9100846
107 rdf:type schema:PropertyValue
108 N7935be1682f74309b433c48fd4c98f8c rdf:first sg:person.01100506032.35
109 rdf:rest Nc1563b68aafc4a0f9cda470591af0a6b
110 N81ffa62a017d4ff181847080ec2523c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name DNA Methylation
112 rdf:type schema:DefinedTerm
113 N8353f0a200d148afaef2dbc42b564598 schema:name pubmed_id
114 schema:value 21660454
115 rdf:type schema:PropertyValue
116 N8df59c6d19684c8b805f049513229a45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Environmental Exposure
118 rdf:type schema:DefinedTerm
119 N928d705383194681886ab09d0b55722c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Middle Aged
121 rdf:type schema:DefinedTerm
122 Na95c1056750a405389873980a4b1ec3d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Tobacco Smoke Pollution
124 rdf:type schema:DefinedTerm
125 Nb601caf332404f71a7b9587f7a085a42 rdf:first sg:person.01065166305.40
126 rdf:rest rdf:nil
127 Nbd6da72294e34c6db53120729804dce1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Male
129 rdf:type schema:DefinedTerm
130 Nc1563b68aafc4a0f9cda470591af0a6b rdf:first sg:person.0665636641.91
131 rdf:rest N3a4c7c4bd9b04be4ba3ecd03fc10ada2
132 Nc59e75352d4a4f88b79238e758f69f66 rdf:first sg:person.01077706721.23
133 rdf:rest N1fc3798523494f23a1bbcb273d7c8914
134 Nd2e3183978984e0db395aeddad8a4d65 rdf:first sg:person.01226701141.38
135 rdf:rest N7935be1682f74309b433c48fd4c98f8c
136 Nd9ede3f576f442ffb36845a7eaf3846a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Female
138 rdf:type schema:DefinedTerm
139 Ndedaaabcc1204fdfa09e7fa7109bff33 schema:name dimensions_id
140 schema:value pub.1008764704
141 rdf:type schema:PropertyValue
142 Nea5d8532263046ed898a4c4d839a598e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Smoke
144 rdf:type schema:DefinedTerm
145 Neefe1c1451f64d848fbb2625a99f8d2b schema:name Springer Nature - SN SciGraph project
146 rdf:type schema:Organization
147 Nfe6cda88ff074791b52ede5c6e09e975 rdf:first sg:person.0603341031.23
148 rdf:rest Nb601caf332404f71a7b9587f7a085a42
149 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
150 schema:name Medical and Health Sciences
151 rdf:type schema:DefinedTerm
152 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
153 schema:name Public Health and Health Services
154 rdf:type schema:DefinedTerm
155 sg:grant.2438839 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-011-9788-6
156 rdf:type schema:MonetaryGrant
157 sg:grant.2439959 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-011-9788-6
158 rdf:type schema:MonetaryGrant
159 sg:grant.2471226 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-011-9788-6
160 rdf:type schema:MonetaryGrant
161 sg:grant.2478773 http://pending.schema.org/fundedItem sg:pub.10.1007/s10552-011-9788-6
162 rdf:type schema:MonetaryGrant
163 sg:journal.1100917 schema:issn 0957-5243
164 1573-7225
165 schema:name Cancer Causes & Control
166 rdf:type schema:Periodical
167 sg:person.01065166305.40 schema:affiliation https://www.grid.ac/institutes/grid.40263.33
168 schema:familyName Marsit
169 schema:givenName Carmen J.
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065166305.40
171 rdf:type schema:Person
172 sg:person.01077706721.23 schema:affiliation https://www.grid.ac/institutes/grid.254880.3
173 schema:familyName Schned
174 schema:givenName Alan R.
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077706721.23
176 rdf:type schema:Person
177 sg:person.01100506032.35 schema:affiliation https://www.grid.ac/institutes/grid.40263.33
178 schema:familyName Christensen
179 schema:givenName Brock C.
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100506032.35
181 rdf:type schema:Person
182 sg:person.01170010143.70 schema:affiliation https://www.grid.ac/institutes/grid.40263.33
183 schema:familyName Andres Houseman
184 schema:givenName E.
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170010143.70
186 rdf:type schema:Person
187 sg:person.01226701141.38 schema:affiliation https://www.grid.ac/institutes/grid.40263.33
188 schema:familyName Wilhelm-Benartzi
189 schema:givenName Charlotte S.
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226701141.38
191 rdf:type schema:Person
192 sg:person.0603341031.23 schema:affiliation https://www.grid.ac/institutes/grid.40263.33
193 schema:familyName Kelsey
194 schema:givenName Karl T.
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603341031.23
196 rdf:type schema:Person
197 sg:person.0665636641.91 schema:affiliation https://www.grid.ac/institutes/grid.40263.33
198 schema:familyName Koestler
199 schema:givenName Devin C.
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665636641.91
201 rdf:type schema:Person
202 sg:person.07573167157.40 schema:affiliation https://www.grid.ac/institutes/grid.254880.3
203 schema:familyName Karagas
204 schema:givenName Margaret R.
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07573167157.40
206 rdf:type schema:Person
207 sg:pub.10.1023/a:1013954932343 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018978333
208 https://doi.org/10.1023/a:1013954932343
209 rdf:type schema:CreativeWork
210 sg:pub.10.1023/a:1018453104303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052300916
211 https://doi.org/10.1023/a:1018453104303
212 rdf:type schema:CreativeWork
213 sg:pub.10.1023/b:caco.0000036452.55199.a3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011609224
214 https://doi.org/10.1023/b:caco.0000036452.55199.a3
215 rdf:type schema:CreativeWork
216 sg:pub.10.1038/ncpuro0318 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045623818
217 https://doi.org/10.1038/ncpuro0318
218 rdf:type schema:CreativeWork
219 sg:pub.10.1038/ni1558 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049440431
220 https://doi.org/10.1038/ni1558
221 rdf:type schema:CreativeWork
222 sg:pub.10.1038/nrc1799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041169608
223 https://doi.org/10.1038/nrc1799
224 rdf:type schema:CreativeWork
225 sg:pub.10.1038/nrg816 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053491434
226 https://doi.org/10.1038/nrg816
227 rdf:type schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1075303191 schema:CreativeWork
229 https://app.dimensions.ai/details/publication/pub.1077285953 schema:CreativeWork
230 https://doi.org/10.1002/ijc.11467 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047900870
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1002/ijc.2910440411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010898321
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/jcp.22209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053287283
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/0092-8674(86)90360-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054549956
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/0304-3835(87)90079-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019918293
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/j.ccr.2004.08.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012235373
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/j.lfs.2010.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040946679
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/j.molmed.2009.12.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047503737
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/j.mrgentox.2006.02.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022709676
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/j.yexcr.2010.03.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008506367
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/s0140-6736(09)60491-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017197399
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1042/bst0371254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004867967
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1056/nejm199905063401810 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027579263
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1056/nejmoa043331 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029207836
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1080/03008880802285032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007941239
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1081/gnc-120021372 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058431294
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1093/acprof:oso/9780195149616.003.0058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1088889222
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1093/carcin/bgi172 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037478026
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1093/carcin/bgm116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038496205
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1093/jat/30.3.187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044989538
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1093/jnci/93.5.378 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026600565
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1093/jnci/djp361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051754382
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1093/nar/gkj468 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038984084
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1093/oxfordjournals.aje.a113980 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080057177
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1101/gr.4410706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033075033
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1111/j.1467-9868.2004.00439.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1007395272
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1126/science.1071545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021511972
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1158/0008-5472.can-05-0267 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026512316
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1158/0008-5472.can-05-2580 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005441037
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1158/0008-5472.can-06-4567 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044178352
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1158/1055-9965.epi-06-0636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038301216
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1182/blood-2009-05-222208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007002501
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1289/ehp.98106s41047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064747148
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1371/journal.pgen.1001043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001869456
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1371/journal.pone.0008357 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050617185
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1371/journal.pone.0012334 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039236324
301 rdf:type schema:CreativeWork
302 https://doi.org/10.2174/156652408785747979 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069185942
303 rdf:type schema:CreativeWork
304 https://doi.org/10.3892/ijmm.14.5.825 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071505862
305 rdf:type schema:CreativeWork
306 https://www.grid.ac/institutes/grid.254880.3 schema:alternateName Dartmouth College
307 schema:name Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
308 Department of Pathology, Dartmouth Medical School, Lebanon, NH, USA
309 rdf:type schema:Organization
310 https://www.grid.ac/institutes/grid.40263.33 schema:alternateName Brown University
311 schema:name Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA
312 Department of Pathology and Laboratory Medicine, Brown University, Box G-E537, 02912, Providence, RI, USA
313 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...