Ontology type: schema:ScholarlyArticle
2015-04
AUTHORSLorraine L. Lipscombe, Hadas D. Fischer, Peter C. Austin, Longdi Fu, R. Liisa Jaakkimainen, Ophira Ginsburg, Paula A. Rochon, Steven Narod, Lawrence Paszat
ABSTRACTWomen with diabetes have higher breast cancer incidence and mortality. The purpose of this study was to examine the impact of diabetes on stage at breast cancer diagnosis, as a possible reason for their higher mortality. Using population-based health databases from Ontario, Canada, this retrospective cohort study examined stage at diagnosis (II, III, or IV vs I) among women aged 20-105 years who were newly diagnosed with invasive breast cancer between 2007 and 2012. We compared those with diabetes to those without diabetes. Diabetes was defined based on medical records using a validated algorithm. Among 38,407 women with breast cancer, 6115 (15.9 %) women had diabetes. Breast cancer patients with diabetes were significantly more likely to present with advanced-stage breast cancer than those without diabetes. After adjustment for mammograms and other covariates, diabetes was associated with a significantly increased risk of Stage II [adjusted odds ratio (aOR) 1.14, 95 % confidence interval (CI) 1.07, 1.22], Stage III (aOR 1.21, 95 % CI 1.11, 1.33), and Stage IV (aOR 1.16, 95 % CI 1.01, 1.33) versus Stage I breast cancer. Women with diabetes had a higher risk of lymph node metastases (aOR 1.16, 95 % CI 1.06, 1.27) and tumors with size over 2 cm (aOR 1.16, 95 % CI 1.06, 1.28). Diabetes was associated with more advanced-stage breast cancer, even after accounting for differences in screening mammogram use and other factors. Our findings suggest that diabetes may predispose to more aggressive breast cancer, which may be a contributor to their higher cancer mortality. More... »
PAGES613-620
http://scigraph.springernature.com/pub.10.1007/s10549-015-3323-5
DOIhttp://dx.doi.org/10.1007/s10549-015-3323-5
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/25779100
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"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"25779100"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"8111104"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s10549-015-3323-5"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1011662195"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s10549-015-3323-5",
"https://app.dimensions.ai/details/publication/pub.1011662195"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T15:43",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000480.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/s10549-015-3323-5"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10549-015-3323-5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10549-015-3323-5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10549-015-3323-5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10549-015-3323-5'
This table displays all metadata directly associated to this object as RDF triples.
321 TRIPLES
21 PREDICATES
83 URIs
37 LITERALS
25 BLANK NODES