Role of Mitochondria in the Mechanisms of Glutamate Toxicity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-06

AUTHORS

N. K. Isaev, N. A. Andreeva, E. V. Stel’mashuk, D. B. Zorov

ABSTRACT

Current data on glutamate-induced functional and morphological changes in mitochondria correlating with or being a result of their membrane potential changes are reviewed. The important role of Ca2+, Na+, and H+ in the potentiation of such changes is considered. It is assumed that glutamate-induced loss of mitochondrial potential is mediated by Ca2+ overload resulting in the induction of nonspecific permeability of the inner mitochondrial membrane. More... »

PAGES

611-618

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10541-005-0160-x

DOI

http://dx.doi.org/10.1007/s10541-005-0160-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038988044

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16038602


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