Enhancement of xylitol productivity and yield using a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis under fully aerobic conditions View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-06-30

AUTHORS

Byoung Sam Ko, Chang Hoon Rhee, Jung Hoe Kim

ABSTRACT

The effects of glycerol and the oxygen transfer rate on the xylitol production rate by a xylitol dehydrogenase gene (XYL2)-disrupted mutant of Candida tropicalis were investigated. The mutant produced xylitol near the almost yield of 100% from d-xylose using glycerol as a co-substrate for cell growth and NADPH regeneration: 50 g d-xylose l−1 was completely converted into xylitol when at least 20 g glycerol l−1 was used as a co-substrate. The xylitol production rate increased with the O2 transfer rate until saturation and it was not necessary to control the dissolved O2 tension precisely. Under the optimum conditions, the volumetric productivity and xylitol yield were 3.2 g l−1 h−1 and 97% (w/w), respectively. More... »

PAGES

1159-1162

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10529-006-9068-9

DOI

http://dx.doi.org/10.1007/s10529-006-9068-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005723899

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16810450


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