Application of a Novel Oscillatory Flow Micro-bioreactor to the Production of γ-decalactone in a Two Immiscible Liquid Phase Medium View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-04

AUTHORS

N. Reis, C. N. Gonçalves, M. Aguedo, N. Gomes, J. A. Teixeira, A. A. Vicente

ABSTRACT

A novel micro-bioreactor based on the oscillatory flow technology was applied to the scale-down of the biotechnological production of gamma-decalactone. A decrease up to 50% of the time required to obtain the maximum concentration of the compound was observed, when compared with other scaled-down platforms (stirred tank bioreactor or shake flask). A three-fold increase in gamma-decalactone productivity was obtained by increasing oscillatory mixing intensity from Re(o) approximately 482 to Re(o) approximately 1447. This was presumably related to the effective contribution of the reactor geometry to enhanced mass transfer rates between the two immiscible liquid phases involved in the process by increasing the interfacial area. More... »

PAGES

485-490

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10529-006-0003-x

DOI

http://dx.doi.org/10.1007/s10529-006-0003-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022082747

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16614930


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