An Application of the Elastic Net for an Endophenotype Analysis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-01

AUTHORS

Dean Palejev, Wookyeon Hwang, Nicole Landi, Maria Eastman, Stephen J. Frost, Robert K. Fulbright, Judith R. Kidd, Kenneth K. Kidd, Graeme F. Mason, W. Einar Mencl, Carolyn Yrigollen, Kenneth R. Pugh, Elena L. Grigorenko

ABSTRACT

We provide an illustration of an application of the elastic net to a large number of common genetic variants in the context of the search for the genetic bases of an endophenotype conceivably related to individual differences in learning. GABA concentration in the occipital cortex, a critical area for reading, was obtained in a group (n = 76) of children aged 6-10 years. Two extreme groups, high and low, were selected for genotyping with the 650Y Illumina array chip (Ilmn650Y). An elastic net approach was applied to the resulting SNP dataset; 100 SNPs were identified for each chromosome as "interesting" based on having the highest absolute value coefficients. The analyses highlighted chromosomes 15 and 20, which contained 55 candidate genes. The STRING partner analyses of the associated proteins pointed to a number of related genes, most notably, GABA and NTRK receptors. More... »

PAGES

120-124

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10519-011-9443-8

DOI

http://dx.doi.org/10.1007/s10519-011-9443-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009401720

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21229297


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Algorithms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 15", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 20", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dyslexia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endophenotypes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Variation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome-Wide Association Study", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Spectroscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Occipital Lobe", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "gamma-Aminobutyric Acid", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Yale University, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Palejev", 
        "givenName": "Dean", 
        "id": "sg:person.0754731357.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754731357.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "LG Corporation (South Korea)", 
          "id": "https://www.grid.ac/institutes/grid.464630.3", 
          "name": [
            "Home Entertainment Company, LG Electronics, Seoul, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hwang", 
        "givenName": "Wookyeon", 
        "id": "sg:person.01135540051.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01135540051.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Haskins Laboratories", 
          "id": "https://www.grid.ac/institutes/grid.249445.a", 
          "name": [
            "Yale University, New Haven, CT, USA", 
            "Haskins Laboratories, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Landi", 
        "givenName": "Nicole", 
        "id": "sg:person.01152602713.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152602713.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Yale University, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eastman", 
        "givenName": "Maria", 
        "id": "sg:person.01251766451.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251766451.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Haskins Laboratories", 
          "id": "https://www.grid.ac/institutes/grid.249445.a", 
          "name": [
            "Haskins Laboratories, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Frost", 
        "givenName": "Stephen J.", 
        "id": "sg:person.01226224252.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226224252.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Yale University, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fulbright", 
        "givenName": "Robert K.", 
        "id": "sg:person.01365755172.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365755172.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Yale University, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kidd", 
        "givenName": "Judith R.", 
        "id": "sg:person.01216111541.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216111541.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Yale University, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kidd", 
        "givenName": "Kenneth K.", 
        "id": "sg:person.01264224741.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264224741.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Yale University, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mason", 
        "givenName": "Graeme F.", 
        "id": "sg:person.01210242533.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210242533.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Haskins Laboratories", 
          "id": "https://www.grid.ac/institutes/grid.249445.a", 
          "name": [
            "Haskins Laboratories, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mencl", 
        "givenName": "W. Einar", 
        "id": "sg:person.01150107261.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150107261.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, Davis", 
          "id": "https://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "University of California, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yrigollen", 
        "givenName": "Carolyn", 
        "id": "sg:person.01121057711.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121057711.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Haskins Laboratories", 
          "id": "https://www.grid.ac/institutes/grid.249445.a", 
          "name": [
            "Yale University, New Haven, CT, USA", 
            "Haskins Laboratories, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pugh", 
        "givenName": "Kenneth R.", 
        "id": "sg:person.01040175463.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040175463.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Moscow State University", 
          "id": "https://www.grid.ac/institutes/grid.14476.30", 
          "name": [
            "Yale University, New Haven, CT, USA", 
            "Child Study Center, Yale University, 230 South Fontage Road, 06519-1124, New Haven, CT, USA", 
            "Columbia University, New York, NY, USA", 
            "Moscow State University, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grigorenko", 
        "givenName": "Elena L.", 
        "id": "sg:person.01207514351.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207514351.67"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1471-2105-11-311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001053475", 
          "https://doi.org/10.1186/1471-2105-11-311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08494", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005147626", 
          "https://doi.org/10.1038/nature08494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08494", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005147626", 
          "https://doi.org/10.1038/nature08494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.1910380521", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013449902"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1054-3589(10)58007-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017705318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1022356842", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-0-387-21606-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022356842", 
          "https://doi.org/10.1007/978-0-387-21606-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-0-387-21606-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022356842", 
          "https://doi.org/10.1007/978-0-387-21606-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkn760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032318578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.1910290613", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033561485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1467-9868.2005.00503.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043971564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.90.12.5662", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044174299"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/092986709787549271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069161429"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-01", 
    "datePublishedReg": "2011-01-01", 
    "description": "We provide an illustration of an application of the elastic net to a large number of common genetic variants in the context of the search for the genetic bases of an endophenotype conceivably related to individual differences in learning. GABA concentration in the occipital cortex, a critical area for reading, was obtained in a group (n = 76) of children aged 6-10 years. Two extreme groups, high and low, were selected for genotyping with the 650Y Illumina array chip (Ilmn650Y). An elastic net approach was applied to the resulting SNP dataset; 100 SNPs were identified for each chromosome as \"interesting\" based on having the highest absolute value coefficients. The analyses highlighted chromosomes 15 and 20, which contained 55 candidate genes. The STRING partner analyses of the associated proteins pointed to a number of related genes, most notably, GABA and NTRK receptors.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10519-011-9443-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2440581", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2443054", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2527244", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2436450", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2436384", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2574995", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2488943", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2564814", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1013844", 
        "issn": [
          "0001-8244", 
          "1573-3297"
        ], 
        "name": "Behavior Genetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "41"
      }
    ], 
    "name": "An Application of the Elastic Net for an Endophenotype Analysis", 
    "pagination": "120-124", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "2cc93d459376337f900360d500929ed1e7aaa5be8b88bbd0157824326784ccb0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21229297"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0251711"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10519-011-9443-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1009401720"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10519-011-9443-8", 
      "https://app.dimensions.ai/details/publication/pub.1009401720"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:53", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89793_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10519-011-9443-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10519-011-9443-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10519-011-9443-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10519-011-9443-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10519-011-9443-8'


 

This table displays all metadata directly associated to this object as RDF triples.

292 TRIPLES      21 PREDICATES      58 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10519-011-9443-8 schema:about N04c54f62eb5b481986e49d6c1343366d
2 N091e0036e6cf4bd8906ace00ffd48600
3 N10fa360cb8914bf1aad44a838d98aabe
4 N1db306d4304f4b2b9c207cb3b9f41055
5 N3f45d1fe431e4bdd8945d91b61bcbe74
6 N41fd70d0d6b74acdb65855da1cd10502
7 N4b9e60f03a9d46a1b72fda73ba1056df
8 N50f6307eddbb4582a0264fe3d66aab92
9 N5461104c3e6d4f38a83ea9b1d542e9bc
10 N65e701eb0bf7453ea6bf7006d9d78738
11 N66bba5ece63b435897d21960a0cc64b0
12 N70f15b1525a3481fb86129f215c088b4
13 N88203831ea2e4edca1dfede1122404e9
14 N89bea4ae51dc4e07af12f447f1e23d19
15 N9d0e78802c624fee849856a2783dd1e3
16 N9e70061d4c104c25ae7911bc1a32f72c
17 Na6dbcae2c9924935a8f442f444f12035
18 Nbb19aaacf5464b24ade497f286b811c2
19 anzsrc-for:06
20 anzsrc-for:0604
21 schema:author Nb75a7c8d7c3f47d7bfa67778f07448c8
22 schema:citation sg:pub.10.1007/978-0-387-21606-5
23 sg:pub.10.1038/nature08494
24 sg:pub.10.1186/1471-2105-11-311
25 https://app.dimensions.ai/details/publication/pub.1022356842
26 https://doi.org/10.1002/mrm.1910290613
27 https://doi.org/10.1002/mrm.1910380521
28 https://doi.org/10.1016/s1054-3589(10)58007-4
29 https://doi.org/10.1073/pnas.90.12.5662
30 https://doi.org/10.1093/nar/gkn760
31 https://doi.org/10.1111/j.1467-9868.2005.00503.x
32 https://doi.org/10.2174/092986709787549271
33 schema:datePublished 2011-01
34 schema:datePublishedReg 2011-01-01
35 schema:description We provide an illustration of an application of the elastic net to a large number of common genetic variants in the context of the search for the genetic bases of an endophenotype conceivably related to individual differences in learning. GABA concentration in the occipital cortex, a critical area for reading, was obtained in a group (n = 76) of children aged 6-10 years. Two extreme groups, high and low, were selected for genotyping with the 650Y Illumina array chip (Ilmn650Y). An elastic net approach was applied to the resulting SNP dataset; 100 SNPs were identified for each chromosome as "interesting" based on having the highest absolute value coefficients. The analyses highlighted chromosomes 15 and 20, which contained 55 candidate genes. The STRING partner analyses of the associated proteins pointed to a number of related genes, most notably, GABA and NTRK receptors.
36 schema:genre research_article
37 schema:inLanguage en
38 schema:isAccessibleForFree true
39 schema:isPartOf N04decc5eafc6437882c6e093d087a40c
40 Ncd2af15a71be413ab140f825004d27a4
41 sg:journal.1013844
42 schema:name An Application of the Elastic Net for an Endophenotype Analysis
43 schema:pagination 120-124
44 schema:productId N6720263c241c40429b652188b72f7d64
45 N68761ef4a9d94f5d93b7dfb9f35d6fec
46 Nb9734a49343e4dfb9c7792e6c916fbdd
47 Ncdb6895044c149f2affddb2e265d78cd
48 Ndc960c62ab0c4a559a8482f004a6668f
49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009401720
50 https://doi.org/10.1007/s10519-011-9443-8
51 schema:sdDatePublished 2019-04-11T09:53
52 schema:sdLicense https://scigraph.springernature.com/explorer/license/
53 schema:sdPublisher N37439cfd85d04665b2ac1dd91c8b8d84
54 schema:url https://link.springer.com/10.1007%2Fs10519-011-9443-8
55 sgo:license sg:explorer/license/
56 sgo:sdDataset articles
57 rdf:type schema:ScholarlyArticle
58 N04c54f62eb5b481986e49d6c1343366d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
59 schema:name Dyslexia
60 rdf:type schema:DefinedTerm
61 N04decc5eafc6437882c6e093d087a40c schema:issueNumber 1
62 rdf:type schema:PublicationIssue
63 N091e0036e6cf4bd8906ace00ffd48600 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name Phenotype
65 rdf:type schema:DefinedTerm
66 N0ebd08ec080343d29db64d84f3512bb2 rdf:first sg:person.01152602713.85
67 rdf:rest Nb6b90ace611a4eda88bbf727cb889eda
68 N10fa360cb8914bf1aad44a838d98aabe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Magnetic Resonance Spectroscopy
70 rdf:type schema:DefinedTerm
71 N1db306d4304f4b2b9c207cb3b9f41055 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name gamma-Aminobutyric Acid
73 rdf:type schema:DefinedTerm
74 N244e1df8206e492598e8857ff0809a3e rdf:first sg:person.01040175463.18
75 rdf:rest Nd538dbd5e90e44949bb78c2922ef167d
76 N2a263dd4693242c5923f849402babcf3 rdf:first sg:person.01264224741.31
77 rdf:rest N8c103e35ae44423a827d6dce09d418ff
78 N2b2071c0d3dd4badb4de2261b56b29cc rdf:first sg:person.01121057711.20
79 rdf:rest N244e1df8206e492598e8857ff0809a3e
80 N37439cfd85d04665b2ac1dd91c8b8d84 schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 N3f45d1fe431e4bdd8945d91b61bcbe74 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Polymorphism, Single Nucleotide
84 rdf:type schema:DefinedTerm
85 N41fd70d0d6b74acdb65855da1cd10502 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Male
87 rdf:type schema:DefinedTerm
88 N4b9e60f03a9d46a1b72fda73ba1056df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Chromosomes, Human, Pair 20
90 rdf:type schema:DefinedTerm
91 N50f6307eddbb4582a0264fe3d66aab92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Humans
93 rdf:type schema:DefinedTerm
94 N5461104c3e6d4f38a83ea9b1d542e9bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Occipital Lobe
96 rdf:type schema:DefinedTerm
97 N55911181a14e4e4cae9945fed2a950ba rdf:first sg:person.01216111541.41
98 rdf:rest N2a263dd4693242c5923f849402babcf3
99 N65e701eb0bf7453ea6bf7006d9d78738 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Genotype
101 rdf:type schema:DefinedTerm
102 N66bba5ece63b435897d21960a0cc64b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Models, Genetic
104 rdf:type schema:DefinedTerm
105 N6720263c241c40429b652188b72f7d64 schema:name dimensions_id
106 schema:value pub.1009401720
107 rdf:type schema:PropertyValue
108 N68761ef4a9d94f5d93b7dfb9f35d6fec schema:name doi
109 schema:value 10.1007/s10519-011-9443-8
110 rdf:type schema:PropertyValue
111 N70f15b1525a3481fb86129f215c088b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Female
113 rdf:type schema:DefinedTerm
114 N88203831ea2e4edca1dfede1122404e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Algorithms
116 rdf:type schema:DefinedTerm
117 N89bea4ae51dc4e07af12f447f1e23d19 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Child
119 rdf:type schema:DefinedTerm
120 N8c103e35ae44423a827d6dce09d418ff rdf:first sg:person.01210242533.67
121 rdf:rest N8efea2bbfe164839a5e2d2d098d233de
122 N8efea2bbfe164839a5e2d2d098d233de rdf:first sg:person.01150107261.95
123 rdf:rest N2b2071c0d3dd4badb4de2261b56b29cc
124 N9d0e78802c624fee849856a2783dd1e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Endophenotypes
126 rdf:type schema:DefinedTerm
127 N9e70061d4c104c25ae7911bc1a32f72c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Genome-Wide Association Study
129 rdf:type schema:DefinedTerm
130 Na6dbcae2c9924935a8f442f444f12035 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Chromosomes, Human, Pair 15
132 rdf:type schema:DefinedTerm
133 Nb6b90ace611a4eda88bbf727cb889eda rdf:first sg:person.01251766451.69
134 rdf:rest Nda821a30c3d34e53a0e41f52a3beef77
135 Nb75a7c8d7c3f47d7bfa67778f07448c8 rdf:first sg:person.0754731357.90
136 rdf:rest Nd137faf4a9264a4386d673b7c2b32ece
137 Nb9734a49343e4dfb9c7792e6c916fbdd schema:name pubmed_id
138 schema:value 21229297
139 rdf:type schema:PropertyValue
140 Nbb19aaacf5464b24ade497f286b811c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Genetic Variation
142 rdf:type schema:DefinedTerm
143 Ncd2af15a71be413ab140f825004d27a4 schema:volumeNumber 41
144 rdf:type schema:PublicationVolume
145 Ncdb6895044c149f2affddb2e265d78cd schema:name readcube_id
146 schema:value 2cc93d459376337f900360d500929ed1e7aaa5be8b88bbd0157824326784ccb0
147 rdf:type schema:PropertyValue
148 Nd137faf4a9264a4386d673b7c2b32ece rdf:first sg:person.01135540051.47
149 rdf:rest N0ebd08ec080343d29db64d84f3512bb2
150 Nd538dbd5e90e44949bb78c2922ef167d rdf:first sg:person.01207514351.67
151 rdf:rest rdf:nil
152 Nda821a30c3d34e53a0e41f52a3beef77 rdf:first sg:person.01226224252.78
153 rdf:rest Ne3f0deb01e954879a63065f0ba914383
154 Ndc960c62ab0c4a559a8482f004a6668f schema:name nlm_unique_id
155 schema:value 0251711
156 rdf:type schema:PropertyValue
157 Ne3f0deb01e954879a63065f0ba914383 rdf:first sg:person.01365755172.23
158 rdf:rest N55911181a14e4e4cae9945fed2a950ba
159 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
160 schema:name Biological Sciences
161 rdf:type schema:DefinedTerm
162 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
163 schema:name Genetics
164 rdf:type schema:DefinedTerm
165 sg:grant.2436384 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
166 rdf:type schema:MonetaryGrant
167 sg:grant.2436450 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
168 rdf:type schema:MonetaryGrant
169 sg:grant.2440581 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
170 rdf:type schema:MonetaryGrant
171 sg:grant.2443054 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
172 rdf:type schema:MonetaryGrant
173 sg:grant.2488943 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
174 rdf:type schema:MonetaryGrant
175 sg:grant.2527244 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
176 rdf:type schema:MonetaryGrant
177 sg:grant.2564814 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
178 rdf:type schema:MonetaryGrant
179 sg:grant.2574995 http://pending.schema.org/fundedItem sg:pub.10.1007/s10519-011-9443-8
180 rdf:type schema:MonetaryGrant
181 sg:journal.1013844 schema:issn 0001-8244
182 1573-3297
183 schema:name Behavior Genetics
184 rdf:type schema:Periodical
185 sg:person.01040175463.18 schema:affiliation https://www.grid.ac/institutes/grid.249445.a
186 schema:familyName Pugh
187 schema:givenName Kenneth R.
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040175463.18
189 rdf:type schema:Person
190 sg:person.01121057711.20 schema:affiliation https://www.grid.ac/institutes/grid.27860.3b
191 schema:familyName Yrigollen
192 schema:givenName Carolyn
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121057711.20
194 rdf:type schema:Person
195 sg:person.01135540051.47 schema:affiliation https://www.grid.ac/institutes/grid.464630.3
196 schema:familyName Hwang
197 schema:givenName Wookyeon
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01135540051.47
199 rdf:type schema:Person
200 sg:person.01150107261.95 schema:affiliation https://www.grid.ac/institutes/grid.249445.a
201 schema:familyName Mencl
202 schema:givenName W. Einar
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150107261.95
204 rdf:type schema:Person
205 sg:person.01152602713.85 schema:affiliation https://www.grid.ac/institutes/grid.249445.a
206 schema:familyName Landi
207 schema:givenName Nicole
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152602713.85
209 rdf:type schema:Person
210 sg:person.01207514351.67 schema:affiliation https://www.grid.ac/institutes/grid.14476.30
211 schema:familyName Grigorenko
212 schema:givenName Elena L.
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207514351.67
214 rdf:type schema:Person
215 sg:person.01210242533.67 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
216 schema:familyName Mason
217 schema:givenName Graeme F.
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210242533.67
219 rdf:type schema:Person
220 sg:person.01216111541.41 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
221 schema:familyName Kidd
222 schema:givenName Judith R.
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216111541.41
224 rdf:type schema:Person
225 sg:person.01226224252.78 schema:affiliation https://www.grid.ac/institutes/grid.249445.a
226 schema:familyName Frost
227 schema:givenName Stephen J.
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226224252.78
229 rdf:type schema:Person
230 sg:person.01251766451.69 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
231 schema:familyName Eastman
232 schema:givenName Maria
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251766451.69
234 rdf:type schema:Person
235 sg:person.01264224741.31 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
236 schema:familyName Kidd
237 schema:givenName Kenneth K.
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264224741.31
239 rdf:type schema:Person
240 sg:person.01365755172.23 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
241 schema:familyName Fulbright
242 schema:givenName Robert K.
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365755172.23
244 rdf:type schema:Person
245 sg:person.0754731357.90 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
246 schema:familyName Palejev
247 schema:givenName Dean
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754731357.90
249 rdf:type schema:Person
250 sg:pub.10.1007/978-0-387-21606-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022356842
251 https://doi.org/10.1007/978-0-387-21606-5
252 rdf:type schema:CreativeWork
253 sg:pub.10.1038/nature08494 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005147626
254 https://doi.org/10.1038/nature08494
255 rdf:type schema:CreativeWork
256 sg:pub.10.1186/1471-2105-11-311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001053475
257 https://doi.org/10.1186/1471-2105-11-311
258 rdf:type schema:CreativeWork
259 https://app.dimensions.ai/details/publication/pub.1022356842 schema:CreativeWork
260 https://doi.org/10.1002/mrm.1910290613 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033561485
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1002/mrm.1910380521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013449902
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1016/s1054-3589(10)58007-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017705318
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1073/pnas.90.12.5662 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044174299
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1093/nar/gkn760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032318578
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1111/j.1467-9868.2005.00503.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043971564
271 rdf:type schema:CreativeWork
272 https://doi.org/10.2174/092986709787549271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069161429
273 rdf:type schema:CreativeWork
274 https://www.grid.ac/institutes/grid.14476.30 schema:alternateName Moscow State University
275 schema:name Child Study Center, Yale University, 230 South Fontage Road, 06519-1124, New Haven, CT, USA
276 Columbia University, New York, NY, USA
277 Moscow State University, Moscow, Russia
278 Yale University, New Haven, CT, USA
279 rdf:type schema:Organization
280 https://www.grid.ac/institutes/grid.249445.a schema:alternateName Haskins Laboratories
281 schema:name Haskins Laboratories, New Haven, CT, USA
282 Yale University, New Haven, CT, USA
283 rdf:type schema:Organization
284 https://www.grid.ac/institutes/grid.27860.3b schema:alternateName University of California, Davis
285 schema:name University of California, Davis, CA, USA
286 rdf:type schema:Organization
287 https://www.grid.ac/institutes/grid.464630.3 schema:alternateName LG Corporation (South Korea)
288 schema:name Home Entertainment Company, LG Electronics, Seoul, South Korea
289 rdf:type schema:Organization
290 https://www.grid.ac/institutes/grid.47100.32 schema:alternateName Yale University
291 schema:name Yale University, New Haven, CT, USA
292 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...