Focal Unilateral Traumatic brain injury Causes Delayed Neurodegenerative Changes in the Brain of Rats View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-12

AUTHORS

E. E. Genrikhs, D. N. Voronkov, M. R. Kapkaeva, N. K. Isaev, E. V. Stelmashook

ABSTRACT

A cascade of pathological changes in the intact hemisphere developed in rats 6 months after focal unilateral traumatic brain injury: neuronal degeneration, hyperexpression of α-synuclein, APP (β-amyloid peptide precursor) protein, and glutamine synthetase in cells other than astrocytes. The development of these changes in the contralateral hemisphere indicated the emergence of extensive delayed neurodegenerative processes in the brain after traumatic brain injury, which were characteristic of diseases associated with pathological aging. More... »

PAGES

211-213

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10517-017-3960-2

DOI

http://dx.doi.org/10.1007/s10517-017-3960-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1092986026

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29177900


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