Camel Thorn Extract Reduces Activity of Angiotensin-Converting Enzyme in Rat Aorta Increased during Aging and Treatment with NO-Synthase Inhibitor View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-12

AUTHORS

T. V. Arutyunyan, A. F. Korystova, L. N. Kublik, M. Kh. Levitman, V. V. Shaposhnikova, N. O. Appazov, R. A. Narmanova, S. Zh. Ibadullayeva, Yu. N. Korystov

ABSTRACT

We studied the effect of camel thorn extract on activity of angiotensin-converting enzyme in rat aorta increased in animals during aging or treatment with NO-synthase inhibitor. Intake of camel thorn extract with drinking water reduced activity of angiotensin-converting enzyme; the effect increased with increasing the dose of the extract. Angiotensin-converting enzyme activity in older rats and animals treated with NO-synthase inhibitor decreased to the values observed in young control rats at extract concentration of 0.2%. Comparison of the effects of camel thorn extract with those of flavonoid taxifolin showed that the extract was not inferior to taxifolin in preventing the early stages of aortic atherosclerosis caused by increased activity of angiotensin-converting enzyme. More... »

PAGES

222-224

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10517-014-2727-2

DOI

http://dx.doi.org/10.1007/s10517-014-2727-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041357657

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25432277


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