Analysis of Serum Activities of Matrix Metalloproteinases and α1-Proteinase Inhibitor in Patients with Type 2 Diabetes Mellitus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-03

AUTHORS

O. N. Poteryaeva, G. S. Russkich, L. E. Panin

ABSTRACT

Activities of matrix metalloproteinases 2 and 7 and α1-proteinase inhibitor were measured in patients with type 2 diabetes mellitus. Correlations between enzyme activity and the main parameters of carbohydrate metabolism were studied. In patients, significant reduction of matrix metalloproteinase activity in the serum was noted, which correlated with the decrease in blood concentration of C-peptide (r=0.8). At the same time, serum activity of α1-proteinase inhibitor increased. No significant relationships between patient's age, glucose concentration, fructosamine concentration, and matrix metalloproteinase activity were observed. More... »

PAGES

578-579

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10517-012-1579-x

DOI

http://dx.doi.org/10.1007/s10517-012-1579-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015090424

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22803137


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