Experimental Study of the Effects of Dietressa, a New Weight-Reducing Drug View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-01

AUTHORS

I. A. Kheyfets, L. I. Bugaeva, T. M. Vorob’eva, J. L. Dugina, S. A. Lebedeva, V. I. Petrov, S. A. Sergeeva, O. I. Epstein

ABSTRACT

The capacity of a new drug containing ultra-low doses of antibodies to cannabinoid receptor type 1 (Dietressa) to reduce body weight gain in mice on a high-calorie diet was evaluated, possible mechanisms of drug action were analyzed, and its safety (abuse potential in the reaction of self-stimulation) was evaluated. Dietressa was not inferior to sibutramine in reducing body weight gain in mice and exhibited no abuse potential. More... »

PAGES

321-324

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10517-012-1518-x

DOI

http://dx.doi.org/10.1007/s10517-012-1518-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011108745

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22803076


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