Expression of Molecular Markers in the Tumor and Survival Prognosis in Osteosarcoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-12

AUTHORS

I. V. Boulytcheva, Yu. N. Soloviev, N. E. Kushlinskii, A. N. Mahson

ABSTRACT

Immunohistochemical study of p53, VEGF, Flt-1/VEGFR1 Ab-1, EGFR, HER-2/neu, Bax, and Cox-2 expression in osteosarcomas was carried out in 40 patients aged 16-70 years. Expression of p53 was detected in 27.5% tumors, VEGF in 15%, Flt-1/VEGFR1 Ab-1 in 97.5%, EGFR in 52.5%, HER-2/neu in 32.5%, Bax in 77.8%, and Cox-2 in 32.3% tumors. Multifactorial analysis showed that the expression of HER-2/neu (p=0.004), p53 (p=0.01), and Cox-2 (p=0.04) in osteosarcomas significantly correlated with unfavorable prognosis for overall survival, while HER-2/neu (p=0.02) and Cox-2 (p=0.003) with relapse-free survival. Analysis of HER-2/neu, p53, and Cox-2 expression in the primary tumor should be taken into consideration in the treatment of patients with osteosarcoma. More... »

PAGES

237-242

References to SciGraph publications

  • 2008-02. Livin and Bcl-2 expression in high-grade osteosarcoma in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 2009-11. Cyclooxygenase-2 Overexpression Predicts Poor Survival in Patients with High-grade Extremity Osteosarcoma: A Pilot Study in CLINICAL ORTHOPAEDICS AND RELATED RESEARCH®
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10517-010-1114-x

    DOI

    http://dx.doi.org/10.1007/s10517-010-1114-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1024843927

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21240382


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adolescent", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Antibodies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Biomarkers, Tumor", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bone Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cyclooxygenase 2", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "ErbB Receptors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene Expression Regulation, Neoplastic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Immunohistochemistry", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Osteosarcoma", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prognosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Receptor, ErbB-2", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tumor Suppressor Protein p53", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Vascular Endothelial Growth Factor A", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Vascular Endothelial Growth Factor Receptor-1", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "bcl-2-Associated X Protein", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "name": [
                "Department of Pathological Anatomy, Moscow Oncological Hospital No. 62, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Boulytcheva", 
            "givenName": "I. V.", 
            "id": "sg:person.016475506214.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016475506214.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medical Sciences", 
              "id": "https://www.grid.ac/institutes/grid.466123.4", 
              "name": [
                "N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Soloviev", 
            "givenName": "Yu. N.", 
            "id": "sg:person.01146751753.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146751753.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medical Sciences", 
              "id": "https://www.grid.ac/institutes/grid.466123.4", 
              "name": [
                "N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kushlinskii", 
            "givenName": "N. E.", 
            "id": "sg:person.010676513277.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010676513277.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Pathological Anatomy, Moscow Oncological Hospital No. 62, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mahson", 
            "givenName": "A. N.", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s11999-009-0814-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010213937", 
              "https://doi.org/10.1007/s11999-009-0814-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1007/s11999-009-0814-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010213937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11999-009-0814-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010213937", 
              "https://doi.org/10.1007/s11999-009-0814-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1007/s11999-009-0814-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010213937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1007/s11999-009-0814-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010213937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0142(19960101)77:1<71::aid-cncr13>3.0.co;2-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033256925"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.prp.2008.01.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037710062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pbc.22178", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040455729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pbc.22178", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040455729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1302/0301-620x.91b6.21853", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043658105"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1081/cnv-120027577", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045107970"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.pai.0000213131.63417.fa", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045518712"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.pai.0000213131.63417.fa", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045518712"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jso.20913", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046362753"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00432-007-0276-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049559174", 
              "https://doi.org/10.1007/s00432-007-0276-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00432-007-0276-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049559174", 
              "https://doi.org/10.1007/s00432-007-0276-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mph.0b013e318197947e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053626975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mph.0b013e318197947e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053626975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mph.0b013e318197947e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053626975"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2010-12", 
        "datePublishedReg": "2010-12-01", 
        "description": "Immunohistochemical study of p53, VEGF, Flt-1/VEGFR1 Ab-1, EGFR, HER-2/neu, Bax, and Cox-2 expression in osteosarcomas was carried out in 40 patients aged 16-70 years. Expression of p53 was detected in 27.5% tumors, VEGF in 15%, Flt-1/VEGFR1 Ab-1 in 97.5%, EGFR in 52.5%, HER-2/neu in 32.5%, Bax in 77.8%, and Cox-2 in 32.3% tumors. Multifactorial analysis showed that the expression of HER-2/neu (p=0.004), p53 (p=0.01), and Cox-2 (p=0.04) in osteosarcomas significantly correlated with unfavorable prognosis for overall survival, while HER-2/neu (p=0.02) and Cox-2 (p=0.003) with relapse-free survival. Analysis of HER-2/neu, p53, and Cox-2 expression in the primary tumor should be taken into consideration in the treatment of patients with osteosarcoma.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s10517-010-1114-x", 
        "inLanguage": [
          "ru"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1017316", 
            "issn": [
              "0007-4888", 
              "1573-8221"
            ], 
            "name": "Bulletin of Experimental Biology and Medicine", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "150"
          }
        ], 
        "name": "Expression of Molecular Markers in the Tumor and Survival Prognosis in Osteosarcoma", 
        "pagination": "237-242", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "765b71f076cb0e6b3f19acaf576716e2ed934b3265a22a28a4df92746b01c9d1"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "21240382"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0372557"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s10517-010-1114-x"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1024843927"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s10517-010-1114-x", 
          "https://app.dimensions.ai/details/publication/pub.1024843927"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T11:03", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000352_0000000352/records_60354_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007%2Fs10517-010-1114-x"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10517-010-1114-x'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10517-010-1114-x'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10517-010-1114-x'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10517-010-1114-x'


     

    This table displays all metadata directly associated to this object as RDF triples.

    204 TRIPLES      21 PREDICATES      59 URIs      40 LITERALS      28 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s10517-010-1114-x schema:about N0fbe0c9083084afe8d4f155f3d4c4a82
    2 N2076b98ae7314d32832792c1b1c5f332
    3 N236310bcb4b048f1a5d7f6a9574d7f5d
    4 N301b518b89eb4b39bdf38fd963042df6
    5 N33564e6badb549c8a9d05de306076c48
    6 N35d306b5888a45f9a3dfaf8b75e4c4e8
    7 N4793cb5d6c874ca3b3cb8614c8d59d9a
    8 N621e209d63e743ea8864571a316d32c7
    9 N6699b1b031ac4a0f978d054c4fb01520
    10 N6ed22cdf42d040db9ac5281878cbed59
    11 Nb08b03ce848c43e8bd1fd4f0f3b32aba
    12 Nb215567d78774d1a8743d3a5e824cfc4
    13 Nb26d9b1c2a8a49939045e7c12a90c333
    14 Nbcfe3607777a4daeab28f6dd2b918f95
    15 Nd1227eaf03ae433cba9bdb9eabb8d549
    16 Necaa1a8e65dd4f50b4c8d4b236066251
    17 Ned5c9a69d92f4475b91468fc997f5bbe
    18 Nf1b57fd71b7b468aa3c6ed5f914b5a76
    19 Nf1f417a470fa4689b2b4d76dab5143f7
    20 anzsrc-for:11
    21 anzsrc-for:1112
    22 schema:author N429a4fffa56244abb6997690349064cc
    23 schema:citation sg:pub.10.1007/s00432-007-0276-z
    24 sg:pub.10.1007/s11999-009-0814-x
    25 https://doi.org/10.1002/(sici)1097-0142(19960101)77:1<71::aid-cncr13>3.0.co;2-5
    26 https://doi.org/10.1002/jso.20913
    27 https://doi.org/10.1002/pbc.22178
    28 https://doi.org/10.1007/s11999-009-0814-x
    29 https://doi.org/10.1016/j.prp.2008.01.015
    30 https://doi.org/10.1081/cnv-120027577
    31 https://doi.org/10.1097/01.pai.0000213131.63417.fa
    32 https://doi.org/10.1097/mph.0b013e318197947e
    33 https://doi.org/10.1302/0301-620x.91b6.21853
    34 schema:datePublished 2010-12
    35 schema:datePublishedReg 2010-12-01
    36 schema:description Immunohistochemical study of p53, VEGF, Flt-1/VEGFR1 Ab-1, EGFR, HER-2/neu, Bax, and Cox-2 expression in osteosarcomas was carried out in 40 patients aged 16-70 years. Expression of p53 was detected in 27.5% tumors, VEGF in 15%, Flt-1/VEGFR1 Ab-1 in 97.5%, EGFR in 52.5%, HER-2/neu in 32.5%, Bax in 77.8%, and Cox-2 in 32.3% tumors. Multifactorial analysis showed that the expression of HER-2/neu (p=0.004), p53 (p=0.01), and Cox-2 (p=0.04) in osteosarcomas significantly correlated with unfavorable prognosis for overall survival, while HER-2/neu (p=0.02) and Cox-2 (p=0.003) with relapse-free survival. Analysis of HER-2/neu, p53, and Cox-2 expression in the primary tumor should be taken into consideration in the treatment of patients with osteosarcoma.
    37 schema:genre research_article
    38 schema:inLanguage ru
    39 schema:isAccessibleForFree false
    40 schema:isPartOf N9caf3374f9f24699b6772e1b3a0c078a
    41 Nac7428f11d1248b8ba1b959c5bb735f7
    42 sg:journal.1017316
    43 schema:name Expression of Molecular Markers in the Tumor and Survival Prognosis in Osteosarcoma
    44 schema:pagination 237-242
    45 schema:productId N1a0e7265ec40443286dc0d66206150df
    46 N905ec7cd488f4f928325c39a4066d5db
    47 Naa396f00f8744701ad0fe52afda8d1b8
    48 Nd71bb2d397304aa187ca5ca6f7d477fc
    49 Nee3a7ac2e1b84b44943f861459b452b1
    50 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024843927
    51 https://doi.org/10.1007/s10517-010-1114-x
    52 schema:sdDatePublished 2019-04-11T11:03
    53 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    54 schema:sdPublisher N4b2d2d772de1482181be5c0a0a35089f
    55 schema:url http://link.springer.com/10.1007%2Fs10517-010-1114-x
    56 sgo:license sg:explorer/license/
    57 sgo:sdDataset articles
    58 rdf:type schema:ScholarlyArticle
    59 N0fbe0c9083084afe8d4f155f3d4c4a82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    60 schema:name Tumor Suppressor Protein p53
    61 rdf:type schema:DefinedTerm
    62 N1a0e7265ec40443286dc0d66206150df schema:name doi
    63 schema:value 10.1007/s10517-010-1114-x
    64 rdf:type schema:PropertyValue
    65 N2076b98ae7314d32832792c1b1c5f332 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    66 schema:name ErbB Receptors
    67 rdf:type schema:DefinedTerm
    68 N236310bcb4b048f1a5d7f6a9574d7f5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    69 schema:name Adult
    70 rdf:type schema:DefinedTerm
    71 N301b518b89eb4b39bdf38fd963042df6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    72 schema:name Vascular Endothelial Growth Factor Receptor-1
    73 rdf:type schema:DefinedTerm
    74 N33564e6badb549c8a9d05de306076c48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    75 schema:name Immunohistochemistry
    76 rdf:type schema:DefinedTerm
    77 N35d306b5888a45f9a3dfaf8b75e4c4e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    78 schema:name Humans
    79 rdf:type schema:DefinedTerm
    80 N429a4fffa56244abb6997690349064cc rdf:first sg:person.016475506214.27
    81 rdf:rest N7701023b13ec4c728a184e56880b23c8
    82 N4793cb5d6c874ca3b3cb8614c8d59d9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    83 schema:name bcl-2-Associated X Protein
    84 rdf:type schema:DefinedTerm
    85 N4b2d2d772de1482181be5c0a0a35089f schema:name Springer Nature - SN SciGraph project
    86 rdf:type schema:Organization
    87 N621e209d63e743ea8864571a316d32c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    88 schema:name Aged
    89 rdf:type schema:DefinedTerm
    90 N6699b1b031ac4a0f978d054c4fb01520 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    91 schema:name Adolescent
    92 rdf:type schema:DefinedTerm
    93 N6ed22cdf42d040db9ac5281878cbed59 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Osteosarcoma
    95 rdf:type schema:DefinedTerm
    96 N758838bfb5f7459e9a516573395ab65c schema:name Department of Pathological Anatomy, Moscow Oncological Hospital No. 62, Moscow, Russia
    97 rdf:type schema:Organization
    98 N7701023b13ec4c728a184e56880b23c8 rdf:first sg:person.01146751753.18
    99 rdf:rest N7d9a02874d6c4fd79f2621484a2e9066
    100 N7d9a02874d6c4fd79f2621484a2e9066 rdf:first sg:person.010676513277.84
    101 rdf:rest Na81d67381840486da32f0b8eb7e189bb
    102 N905ec7cd488f4f928325c39a4066d5db schema:name pubmed_id
    103 schema:value 21240382
    104 rdf:type schema:PropertyValue
    105 N9caf3374f9f24699b6772e1b3a0c078a schema:volumeNumber 150
    106 rdf:type schema:PublicationVolume
    107 Na81d67381840486da32f0b8eb7e189bb rdf:first Ncb5e6aad75564e5db7e3316c1dac6e2d
    108 rdf:rest rdf:nil
    109 Naa396f00f8744701ad0fe52afda8d1b8 schema:name dimensions_id
    110 schema:value pub.1024843927
    111 rdf:type schema:PropertyValue
    112 Nac7428f11d1248b8ba1b959c5bb735f7 schema:issueNumber 2
    113 rdf:type schema:PublicationIssue
    114 Nb08b03ce848c43e8bd1fd4f0f3b32aba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Middle Aged
    116 rdf:type schema:DefinedTerm
    117 Nb215567d78774d1a8743d3a5e824cfc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Bone Neoplasms
    119 rdf:type schema:DefinedTerm
    120 Nb26d9b1c2a8a49939045e7c12a90c333 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Cyclooxygenase 2
    122 rdf:type schema:DefinedTerm
    123 Nbcfe3607777a4daeab28f6dd2b918f95 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    124 schema:name Prognosis
    125 rdf:type schema:DefinedTerm
    126 Nc5759e1a052d48f8847e613bf7dc748d schema:name Department of Pathological Anatomy, Moscow Oncological Hospital No. 62, Moscow, Russia
    127 rdf:type schema:Organization
    128 Ncb5e6aad75564e5db7e3316c1dac6e2d schema:affiliation N758838bfb5f7459e9a516573395ab65c
    129 schema:familyName Mahson
    130 schema:givenName A. N.
    131 rdf:type schema:Person
    132 Nd1227eaf03ae433cba9bdb9eabb8d549 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    133 schema:name Vascular Endothelial Growth Factor A
    134 rdf:type schema:DefinedTerm
    135 Nd71bb2d397304aa187ca5ca6f7d477fc schema:name readcube_id
    136 schema:value 765b71f076cb0e6b3f19acaf576716e2ed934b3265a22a28a4df92746b01c9d1
    137 rdf:type schema:PropertyValue
    138 Necaa1a8e65dd4f50b4c8d4b236066251 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    139 schema:name Biomarkers, Tumor
    140 rdf:type schema:DefinedTerm
    141 Ned5c9a69d92f4475b91468fc997f5bbe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    142 schema:name Receptor, ErbB-2
    143 rdf:type schema:DefinedTerm
    144 Nee3a7ac2e1b84b44943f861459b452b1 schema:name nlm_unique_id
    145 schema:value 0372557
    146 rdf:type schema:PropertyValue
    147 Nf1b57fd71b7b468aa3c6ed5f914b5a76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Gene Expression Regulation, Neoplastic
    149 rdf:type schema:DefinedTerm
    150 Nf1f417a470fa4689b2b4d76dab5143f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    151 schema:name Antibodies
    152 rdf:type schema:DefinedTerm
    153 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    154 schema:name Medical and Health Sciences
    155 rdf:type schema:DefinedTerm
    156 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    157 schema:name Oncology and Carcinogenesis
    158 rdf:type schema:DefinedTerm
    159 sg:journal.1017316 schema:issn 0007-4888
    160 1573-8221
    161 schema:name Bulletin of Experimental Biology and Medicine
    162 rdf:type schema:Periodical
    163 sg:person.010676513277.84 schema:affiliation https://www.grid.ac/institutes/grid.466123.4
    164 schema:familyName Kushlinskii
    165 schema:givenName N. E.
    166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010676513277.84
    167 rdf:type schema:Person
    168 sg:person.01146751753.18 schema:affiliation https://www.grid.ac/institutes/grid.466123.4
    169 schema:familyName Soloviev
    170 schema:givenName Yu. N.
    171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146751753.18
    172 rdf:type schema:Person
    173 sg:person.016475506214.27 schema:affiliation Nc5759e1a052d48f8847e613bf7dc748d
    174 schema:familyName Boulytcheva
    175 schema:givenName I. V.
    176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016475506214.27
    177 rdf:type schema:Person
    178 sg:pub.10.1007/s00432-007-0276-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1049559174
    179 https://doi.org/10.1007/s00432-007-0276-z
    180 rdf:type schema:CreativeWork
    181 sg:pub.10.1007/s11999-009-0814-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010213937
    182 https://doi.org/10.1007/s11999-009-0814-x
    183 rdf:type schema:CreativeWork
    184 https://doi.org/10.1002/(sici)1097-0142(19960101)77:1<71::aid-cncr13>3.0.co;2-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033256925
    185 rdf:type schema:CreativeWork
    186 https://doi.org/10.1002/jso.20913 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046362753
    187 rdf:type schema:CreativeWork
    188 https://doi.org/10.1002/pbc.22178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040455729
    189 rdf:type schema:CreativeWork
    190 https://doi.org/10.1007/s11999-009-0814-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010213937
    191 rdf:type schema:CreativeWork
    192 https://doi.org/10.1016/j.prp.2008.01.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037710062
    193 rdf:type schema:CreativeWork
    194 https://doi.org/10.1081/cnv-120027577 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045107970
    195 rdf:type schema:CreativeWork
    196 https://doi.org/10.1097/01.pai.0000213131.63417.fa schema:sameAs https://app.dimensions.ai/details/publication/pub.1045518712
    197 rdf:type schema:CreativeWork
    198 https://doi.org/10.1097/mph.0b013e318197947e schema:sameAs https://app.dimensions.ai/details/publication/pub.1053626975
    199 rdf:type schema:CreativeWork
    200 https://doi.org/10.1302/0301-620x.91b6.21853 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043658105
    201 rdf:type schema:CreativeWork
    202 https://www.grid.ac/institutes/grid.466123.4 schema:alternateName Department of Medical Sciences
    203 schema:name N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia
    204 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...