PrEP Demonstration Project Showed Superior Adherence with Tenofovir Alafenamide/Emtricitabine Compared to Tenofovir Disoproxil Fumarate/Emtricitabine in a Sample of Partnered Sexual ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-11-18

AUTHORS

Gabriel Robles, Daniel Sauermilch, Monica Gandhi, Tyrel J. Starks

ABSTRACT

Sexual minority men (SMM) remain at high risk of HIV infection in the United States, and for those in relationships, dyadic functioning may contextualize prevention decisions. Pre-exposure prophylaxis (PrEP) for HIV prevention was previously limited to tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) until the FDA approved tenofovir alafenamide/FTC (TAF/FTC) for PrEP in 2019. Data regarding substance use, sexual behavior, holding an active PrEP prescription, and type of PrEP regimen (TDF/FTC versus TAF/FTC) were analyzed from a sample of 421 partnered SMM. The majority of the sample on PrEP reported a TDF/FTC prescription as opposed to TAF/FTC. However, SMM reported significantly better adherence to TAF/FTC than TDF/FTC in multivariable models. Novelty of TAF/FTC, treatment fatigue with TDF/FTC, and/or a belief in TAF/FTC’s superior efficacy and mitigated side effects may be plausible contributing factors. More studies using objective adherence metrics and surveys are needed. More... »

PAGES

1299-1305

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10461-020-03095-7

DOI

http://dx.doi.org/10.1007/s10461-020-03095-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1132688812

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33206262


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