3D Bioprinting for Tissue and Organ Fabrication View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-01

AUTHORS

Yu Shrike Zhang, Kan Yue, Julio Aleman, Kamyar Mollazadeh-Moghaddam, Syeda Mahwish Bakht, Jingzhou Yang, Weitao Jia, Valeria Dell’Erba, Pribpandao Assawes, Su Ryon Shin, Mehmet Remzi Dokmeci, Rahmi Oklu, Ali Khademhosseini

ABSTRACT

The field of regenerative medicine has progressed tremendously over the past few decades in its ability to fabricate functional tissue substitutes. Conventional approaches based on scaffolding and microengineering are limited in their capacity of producing tissue constructs with precise biomimetic properties. Three-dimensional (3D) bioprinting technology, on the other hand, promises to bridge the divergence between artificially engineered tissue constructs and native tissues. In a sense, 3D bioprinting offers unprecedented versatility to co-deliver cells and biomaterials with precise control over their compositions, spatial distributions, and architectural accuracy, therefore achieving detailed or even personalized recapitulation of the fine shape, structure, and architecture of target tissues and organs. Here we briefly describe recent progresses of 3D bioprinting technology and associated bioinks suitable for the printing process. We then focus on the applications of this technology in fabrication of biomimetic constructs of several representative tissues and organs, including blood vessel, heart, liver, and cartilage. We finally conclude with future challenges in 3D bioprinting as well as potential solutions for further development. More... »

PAGES

148-163

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10439-016-1612-8

DOI

http://dx.doi.org/10.1007/s10439-016-1612-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045852636

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27126775


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573 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
574 schema:name Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 02139, Cambridge, MA, USA
575 Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 02139, Cambridge, MA, USA
576 Wyss Institute for Biologically Inspired Engineering, Harvard University, 02115, Boston, MA, USA
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578 https://www.grid.ac/institutes/grid.412125.1 schema:alternateName King Abdulaziz University
579 schema:name Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 02139, Cambridge, MA, USA
580 Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Hwayang-dong, Gwangjin-gu, 143-701, Seoul, Republic of Korea
581 Department of Physics, King Abdulaziz University, 21569, Jeddah, Saudi Arabia
582 Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 02139, Cambridge, MA, USA
583 Wyss Institute for Biologically Inspired Engineering, Harvard University, 02115, Boston, MA, USA
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585 https://www.grid.ac/institutes/grid.417468.8 schema:alternateName Mayo Clinic
586 schema:name Division of Vascular & Interventional Radiology, Mayo Clinic, 85259, Scottsdale, AZ, USA
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588 https://www.grid.ac/institutes/grid.418920.6 schema:alternateName COMSATS Institute of Information Technology
589 schema:name Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 02139, Cambridge, MA, USA
590 Comsats Institute of Information and Technology, 45550, Islamabad, Pakistan
591 Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 02139, Cambridge, MA, USA
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593 https://www.grid.ac/institutes/grid.4800.c schema:alternateName Polytechnic University of Turin
594 schema:name Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 02139, Cambridge, MA, USA
595 Department of Biomedical Engineering, Politecnico di Torino, 10129, Turin, Italy
596 Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 02139, Cambridge, MA, USA
597 rdf:type schema:Organization
 




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