Subclinical crystal arthropathy: a silent contributor to inflammation and functional disability in knees with osteoarthritis—an ultrasound study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-01

AUTHORS

Reem Hamdy A. Mohammed, Hanan Kotb, Marian Amir, Andrea Di Matteo

ABSTRACT

PURPOSE: This study aimed at investigating the prevalence of crystal deposits with knee osteoarthritis (OA) by ultrasonography and measure the inflammatory burden associated with crystal deposits in OA using WOMAC score. METHODS: Adult patients with primary knee OA diagnosed according to the American College of Rheumatology criteria were included. Participants were subjected to history taking, clinical examination, knee US, and plain radiography. The EULAR and the OMERACT ultrasonography definitions and scanning protocols were used. RESULTS: Fifty-three patients (44 females, 9 males) were enrolled. Mean values were 53.5 years ± 8.3 SD for age and 42.5 months ± 49.5 SD for disease duration. Crystals were detected by US in 73/106 knees (68.9%). Plain radiography revealed chondrocalcinosis in three patients. Mean values for WOMAC pain, stiffness, and disability scores were 14.38 ± 3.99, 4.93 ± 2.06, and 49.61 ± 13.06, respectively, with insignificant differences relative to presence of crystals (P > 0.05). Regression analysis revealed a 4.1-fold increase in the incidence of sonographic crystals with bursitis (OR = 4.13, CI = 1.5-11.2, p = 0.01) and a 3.2-fold increase in the incidence of sonographic crystals with synovial effusion (OR = 3.16, CI = 1.34-7.44, p = 0.01). CONCLUSION: Subclinical crystals were detected in a considerable number of patients with primary knee OA. The incidence of crystal deposits was significantly higher in patients with bursitis and knee effusion. More... »

PAGES

1-10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10396-018-0912-z

DOI

http://dx.doi.org/10.1007/s10396-018-0912-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107665328

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30327988


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Cairo University hospitals", 
          "id": "https://www.grid.ac/institutes/grid.476980.4", 
          "name": [
            "Department of Rheumatology and Rehabilitation, School of Medicine, Cairo University Hospitals, Cairo, Egypt"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mohammed", 
        "givenName": "Reem Hamdy A.", 
        "id": "sg:person.0717755022.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717755022.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cairo University hospitals", 
          "id": "https://www.grid.ac/institutes/grid.476980.4", 
          "name": [
            "Department of Rheumatology and Rehabilitation, School of Medicine, Cairo University Hospitals, Cairo, Egypt"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kotb", 
        "givenName": "Hanan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cairo University hospitals", 
          "id": "https://www.grid.ac/institutes/grid.476980.4", 
          "name": [
            "Department of Rheumatology and Rehabilitation, School of Medicine, Cairo University Hospitals, Cairo, Egypt"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amir", 
        "givenName": "Marian", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Marche Polytechnic University", 
          "id": "https://www.grid.ac/institutes/grid.7010.6", 
          "name": [
            "Rheumatology Department, Universit\u00e0 Politecnica delle Marche, \u201cCarlo Urbani\u201d Hospital, Iesi, Ancona, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Di Matteo", 
        "givenName": "Andrea", 
        "id": "sg:person.010750005365.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010750005365.55"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1136/annrheumdis-2012-202748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001996159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000357756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003776728"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.joca.2006.10.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004023852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2007.082222", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005511612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.joca.2016.01.136", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008772998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/art.1780290816", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008960615"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/j.cpradiol.2007.08.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011816863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/kes433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012282973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.berh.2009.08.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013922269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0092901", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016051407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/kev032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016338821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/acr.21952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016491213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0901-5027(05)80509-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017164833"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002560050132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019611697", 
          "https://doi.org/10.1007/s002560050132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2474-9-116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019861259", 
          "https://doi.org/10.1186/1471-2474-9-116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13075-015-0701-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020144565", 
          "https://doi.org/10.1186/s13075-015-0701-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13075-015-0701-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020144565", 
          "https://doi.org/10.1186/s13075-015-0701-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.semarthrit.2006.08.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027721076"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0049-0172(99)80005-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031091021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10067-014-2505-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031337464", 
          "https://doi.org/10.1007/s10067-014-2505-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/ar4043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031547323", 
          "https://doi.org/10.1186/ar4043"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2011.150508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032678039"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/annrheumdis-2011-201001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032930060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/acr.22190", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033215265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2005.037382", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033669564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04516", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039236419", 
          "https://doi.org/10.1038/nature04516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04516", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039236419", 
          "https://doi.org/10.1038/nature04516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04516", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039236419", 
          "https://doi.org/10.1038/nature04516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.joca.2005.02.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039463631"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2007.069344", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040511466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1012743108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043466725"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.60.7.641", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045755239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2010.139105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048598957"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2004.030387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051124595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.16.4.494", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052069859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1759720x12442112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064077515"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1759720x12442112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064077515"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1211/pj.2013.11126020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064335849"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.h.01385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068901152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.h.01385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068901152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.h.01385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068901152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4081/reumatismo.2011.207", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072203148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074653463", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075282280", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077151912", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077171143", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078788903", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079228949", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079322087", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079536772", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3899/jrheum.161057", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084443726"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-01", 
    "datePublishedReg": "2019-01-01", 
    "description": "PURPOSE: This study aimed at investigating the prevalence of crystal deposits with knee osteoarthritis (OA) by ultrasonography and measure the inflammatory burden associated with crystal deposits in OA using WOMAC score.\nMETHODS: Adult patients with primary knee OA diagnosed according to the American College of Rheumatology criteria were included. Participants were subjected to history taking, clinical examination, knee US, and plain radiography. The EULAR and the OMERACT ultrasonography definitions and scanning protocols were used.\nRESULTS: Fifty-three patients (44 females, 9 males) were enrolled. Mean values were 53.5\u00a0years\u2009\u00b1\u20098.3 SD for age and 42.5\u00a0months\u2009\u00b1\u200949.5 SD for disease duration. Crystals were detected by US in 73/106 knees (68.9%). Plain radiography revealed chondrocalcinosis in three patients. Mean values for WOMAC pain, stiffness, and disability scores were 14.38\u2009\u00b1\u20093.99, 4.93\u2009\u00b1\u20092.06, and 49.61\u2009\u00b1\u200913.06, respectively, with insignificant differences relative to presence of crystals (P\u2009>\u20090.05). Regression analysis revealed a 4.1-fold increase in the incidence of sonographic crystals with bursitis (OR\u2009=\u20094.13, CI\u2009=\u20091.5-11.2, p\u2009=\u20090.01) and a 3.2-fold increase in the incidence of sonographic crystals with synovial effusion (OR\u2009=\u20093.16, CI\u2009=\u20091.34-7.44, p\u2009=\u20090.01).\nCONCLUSION: Subclinical crystals were detected in a considerable number of patients with primary knee OA. The incidence of crystal deposits was significantly higher in patients with bursitis and knee effusion.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10396-018-0912-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1029940", 
        "issn": [
          "1346-4523", 
          "1613-2254"
        ], 
        "name": "Journal of Medical Ultrasonics", 
        "type": "Periodical"
      }
    ], 
    "name": "Subclinical crystal arthropathy: a silent contributor to inflammation and functional disability in knees with osteoarthritis\u2014an ultrasound study", 
    "pagination": "1-10", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9de3f17224f61fdd59ca02054f618542295df40dcaff0d5b3018a54a7bb913d2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30327988"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101128385"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10396-018-0912-z"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1107665328"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10396-018-0912-z", 
      "https://app.dimensions.ai/details/publication/pub.1107665328"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:28", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000563.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10396-018-0912-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10396-018-0912-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10396-018-0912-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10396-018-0912-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10396-018-0912-z'


 

This table displays all metadata directly associated to this object as RDF triples.

218 TRIPLES      21 PREDICATES      72 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10396-018-0912-z schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N021547ffb95048e3b92e9026cda4fb11
4 schema:citation sg:pub.10.1007/s002560050132
5 sg:pub.10.1007/s10067-014-2505-6
6 sg:pub.10.1038/nature04516
7 sg:pub.10.1186/1471-2474-9-116
8 sg:pub.10.1186/ar4043
9 sg:pub.10.1186/s13075-015-0701-7
10 https://app.dimensions.ai/details/publication/pub.1074653463
11 https://app.dimensions.ai/details/publication/pub.1075282280
12 https://app.dimensions.ai/details/publication/pub.1077151912
13 https://app.dimensions.ai/details/publication/pub.1077171143
14 https://app.dimensions.ai/details/publication/pub.1078788903
15 https://app.dimensions.ai/details/publication/pub.1079228949
16 https://app.dimensions.ai/details/publication/pub.1079322087
17 https://app.dimensions.ai/details/publication/pub.1079536772
18 https://doi.org/10.1002/acr.21952
19 https://doi.org/10.1002/acr.22190
20 https://doi.org/10.1002/art.1780290816
21 https://doi.org/10.1016/j.berh.2009.08.012
22 https://doi.org/10.1016/j.joca.2005.02.008
23 https://doi.org/10.1016/j.joca.2006.10.002
24 https://doi.org/10.1016/j.joca.2016.01.136
25 https://doi.org/10.1016/j.semarthrit.2006.08.001
26 https://doi.org/10.1016/s0049-0172(99)80005-5
27 https://doi.org/10.1016/s0901-5027(05)80509-0
28 https://doi.org/10.1067/j.cpradiol.2007.08.001
29 https://doi.org/10.1073/pnas.1012743108
30 https://doi.org/10.1093/rheumatology/kes433
31 https://doi.org/10.1093/rheumatology/kev032
32 https://doi.org/10.1136/annrheumdis-2011-201001
33 https://doi.org/10.1136/annrheumdis-2012-202748
34 https://doi.org/10.1136/ard.16.4.494
35 https://doi.org/10.1136/ard.2004.030387
36 https://doi.org/10.1136/ard.2005.037382
37 https://doi.org/10.1136/ard.2007.069344
38 https://doi.org/10.1136/ard.2007.082222
39 https://doi.org/10.1136/ard.2010.139105
40 https://doi.org/10.1136/ard.2011.150508
41 https://doi.org/10.1136/ard.60.7.641
42 https://doi.org/10.1159/000357756
43 https://doi.org/10.1177/1759720x12442112
44 https://doi.org/10.1211/pj.2013.11126020
45 https://doi.org/10.1371/journal.pone.0092901
46 https://doi.org/10.2106/jbjs.h.01385
47 https://doi.org/10.3899/jrheum.161057
48 https://doi.org/10.4081/reumatismo.2011.207
49 schema:datePublished 2019-01
50 schema:datePublishedReg 2019-01-01
51 schema:description PURPOSE: This study aimed at investigating the prevalence of crystal deposits with knee osteoarthritis (OA) by ultrasonography and measure the inflammatory burden associated with crystal deposits in OA using WOMAC score. METHODS: Adult patients with primary knee OA diagnosed according to the American College of Rheumatology criteria were included. Participants were subjected to history taking, clinical examination, knee US, and plain radiography. The EULAR and the OMERACT ultrasonography definitions and scanning protocols were used. RESULTS: Fifty-three patients (44 females, 9 males) were enrolled. Mean values were 53.5 years ± 8.3 SD for age and 42.5 months ± 49.5 SD for disease duration. Crystals were detected by US in 73/106 knees (68.9%). Plain radiography revealed chondrocalcinosis in three patients. Mean values for WOMAC pain, stiffness, and disability scores were 14.38 ± 3.99, 4.93 ± 2.06, and 49.61 ± 13.06, respectively, with insignificant differences relative to presence of crystals (P > 0.05). Regression analysis revealed a 4.1-fold increase in the incidence of sonographic crystals with bursitis (OR = 4.13, CI = 1.5-11.2, p = 0.01) and a 3.2-fold increase in the incidence of sonographic crystals with synovial effusion (OR = 3.16, CI = 1.34-7.44, p = 0.01). CONCLUSION: Subclinical crystals were detected in a considerable number of patients with primary knee OA. The incidence of crystal deposits was significantly higher in patients with bursitis and knee effusion.
52 schema:genre research_article
53 schema:inLanguage en
54 schema:isAccessibleForFree false
55 schema:isPartOf sg:journal.1029940
56 schema:name Subclinical crystal arthropathy: a silent contributor to inflammation and functional disability in knees with osteoarthritis—an ultrasound study
57 schema:pagination 1-10
58 schema:productId N14afc2b665854c5594df7b4b251c2ab1
59 N1e1b9c4b32274898892c1d675f5c8b42
60 Na435664e3faa45c693ab9696579292b0
61 Na84dabe3ca4f42dab8756f391035f774
62 Nbca1a2be305c4b78b61381a8acfe0b03
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107665328
64 https://doi.org/10.1007/s10396-018-0912-z
65 schema:sdDatePublished 2019-04-10T18:28
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher Nd277f8745a34443bb12281a47ea978e1
68 schema:url https://link.springer.com/10.1007%2Fs10396-018-0912-z
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N021547ffb95048e3b92e9026cda4fb11 rdf:first sg:person.0717755022.14
73 rdf:rest Nb296b13f38b44198ab11fe5ba6016c92
74 N14afc2b665854c5594df7b4b251c2ab1 schema:name readcube_id
75 schema:value 9de3f17224f61fdd59ca02054f618542295df40dcaff0d5b3018a54a7bb913d2
76 rdf:type schema:PropertyValue
77 N1e1b9c4b32274898892c1d675f5c8b42 schema:name nlm_unique_id
78 schema:value 101128385
79 rdf:type schema:PropertyValue
80 N3799403321cf4685a52a9722b26b3655 schema:affiliation https://www.grid.ac/institutes/grid.476980.4
81 schema:familyName Kotb
82 schema:givenName Hanan
83 rdf:type schema:Person
84 N5770148c28b740b89738a0e9c0798f0f schema:affiliation https://www.grid.ac/institutes/grid.476980.4
85 schema:familyName Amir
86 schema:givenName Marian
87 rdf:type schema:Person
88 Na435664e3faa45c693ab9696579292b0 schema:name dimensions_id
89 schema:value pub.1107665328
90 rdf:type schema:PropertyValue
91 Na84dabe3ca4f42dab8756f391035f774 schema:name doi
92 schema:value 10.1007/s10396-018-0912-z
93 rdf:type schema:PropertyValue
94 Nb296b13f38b44198ab11fe5ba6016c92 rdf:first N3799403321cf4685a52a9722b26b3655
95 rdf:rest Nefc1a8ec8e2548aca283717b0a2accb3
96 Nba5887b166664031a6c2e4ccad14f187 rdf:first sg:person.010750005365.55
97 rdf:rest rdf:nil
98 Nbca1a2be305c4b78b61381a8acfe0b03 schema:name pubmed_id
99 schema:value 30327988
100 rdf:type schema:PropertyValue
101 Nd277f8745a34443bb12281a47ea978e1 schema:name Springer Nature - SN SciGraph project
102 rdf:type schema:Organization
103 Nefc1a8ec8e2548aca283717b0a2accb3 rdf:first N5770148c28b740b89738a0e9c0798f0f
104 rdf:rest Nba5887b166664031a6c2e4ccad14f187
105 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
106 schema:name Medical and Health Sciences
107 rdf:type schema:DefinedTerm
108 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
109 schema:name Clinical Sciences
110 rdf:type schema:DefinedTerm
111 sg:journal.1029940 schema:issn 1346-4523
112 1613-2254
113 schema:name Journal of Medical Ultrasonics
114 rdf:type schema:Periodical
115 sg:person.010750005365.55 schema:affiliation https://www.grid.ac/institutes/grid.7010.6
116 schema:familyName Di Matteo
117 schema:givenName Andrea
118 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010750005365.55
119 rdf:type schema:Person
120 sg:person.0717755022.14 schema:affiliation https://www.grid.ac/institutes/grid.476980.4
121 schema:familyName Mohammed
122 schema:givenName Reem Hamdy A.
123 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717755022.14
124 rdf:type schema:Person
125 sg:pub.10.1007/s002560050132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019611697
126 https://doi.org/10.1007/s002560050132
127 rdf:type schema:CreativeWork
128 sg:pub.10.1007/s10067-014-2505-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031337464
129 https://doi.org/10.1007/s10067-014-2505-6
130 rdf:type schema:CreativeWork
131 sg:pub.10.1038/nature04516 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039236419
132 https://doi.org/10.1038/nature04516
133 rdf:type schema:CreativeWork
134 sg:pub.10.1186/1471-2474-9-116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019861259
135 https://doi.org/10.1186/1471-2474-9-116
136 rdf:type schema:CreativeWork
137 sg:pub.10.1186/ar4043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031547323
138 https://doi.org/10.1186/ar4043
139 rdf:type schema:CreativeWork
140 sg:pub.10.1186/s13075-015-0701-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020144565
141 https://doi.org/10.1186/s13075-015-0701-7
142 rdf:type schema:CreativeWork
143 https://app.dimensions.ai/details/publication/pub.1074653463 schema:CreativeWork
144 https://app.dimensions.ai/details/publication/pub.1075282280 schema:CreativeWork
145 https://app.dimensions.ai/details/publication/pub.1077151912 schema:CreativeWork
146 https://app.dimensions.ai/details/publication/pub.1077171143 schema:CreativeWork
147 https://app.dimensions.ai/details/publication/pub.1078788903 schema:CreativeWork
148 https://app.dimensions.ai/details/publication/pub.1079228949 schema:CreativeWork
149 https://app.dimensions.ai/details/publication/pub.1079322087 schema:CreativeWork
150 https://app.dimensions.ai/details/publication/pub.1079536772 schema:CreativeWork
151 https://doi.org/10.1002/acr.21952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016491213
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1002/acr.22190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033215265
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1002/art.1780290816 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008960615
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/j.berh.2009.08.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013922269
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/j.joca.2005.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039463631
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/j.joca.2006.10.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004023852
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/j.joca.2016.01.136 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008772998
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/j.semarthrit.2006.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027721076
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/s0049-0172(99)80005-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031091021
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/s0901-5027(05)80509-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017164833
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1067/j.cpradiol.2007.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011816863
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1073/pnas.1012743108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043466725
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1093/rheumatology/kes433 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012282973
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1093/rheumatology/kev032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016338821
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1136/annrheumdis-2011-201001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032930060
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1136/annrheumdis-2012-202748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001996159
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1136/ard.16.4.494 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052069859
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1136/ard.2004.030387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051124595
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1136/ard.2005.037382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033669564
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1136/ard.2007.069344 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040511466
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1136/ard.2007.082222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005511612
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1136/ard.2010.139105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048598957
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1136/ard.2011.150508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032678039
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1136/ard.60.7.641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045755239
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1159/000357756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003776728
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1177/1759720x12442112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064077515
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1211/pj.2013.11126020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064335849
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1371/journal.pone.0092901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016051407
206 rdf:type schema:CreativeWork
207 https://doi.org/10.2106/jbjs.h.01385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068901152
208 rdf:type schema:CreativeWork
209 https://doi.org/10.3899/jrheum.161057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084443726
210 rdf:type schema:CreativeWork
211 https://doi.org/10.4081/reumatismo.2011.207 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072203148
212 rdf:type schema:CreativeWork
213 https://www.grid.ac/institutes/grid.476980.4 schema:alternateName Cairo University hospitals
214 schema:name Department of Rheumatology and Rehabilitation, School of Medicine, Cairo University Hospitals, Cairo, Egypt
215 rdf:type schema:Organization
216 https://www.grid.ac/institutes/grid.7010.6 schema:alternateName Marche Polytechnic University
217 schema:name Rheumatology Department, Università Politecnica delle Marche, “Carlo Urbani” Hospital, Iesi, Ancona, Italy
218 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...