A case of small-cell esophageal cancer with chronic renal failure undergoing hemodialysis safely treated with cisplatin and etoposide View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-09

AUTHORS

Kentaro Murakami, Yasunori Akutsu, Yukimasa Miyazawa, Kiyohiko Shuto, Toru Shiratori, Masaya Uesato, Isamu Hoshino, Taito Aoki, Hisahiro Matsubara

ABSTRACT

A 54-year-old male undergoing hemodialysis was admitted to our hospital because of difficulty in swallowing. Esophagography and esophageal endoscopy revealed an irregular ulcerated lesion in the cervical esophagus. It was diagnosed as a small-cell esophageal cancer from the biopsy sample. Computed tomography showed a tumor infiltrating the trachea and a few lymph node metastases in the cervix, upper mediastinum, and abdomen. The patient was started on chemotherapy with cisplatin (CDDP) and etoposide (VP-16), which had been reported to be effective for small-cell lung cancer. The patient was treated with CDDP (80 mg/m(2)) on day 1 and VP-16 (100 mg/m(2)) on days 1, 3, and 5, every 4 weeks. On the days of chemotherapy, hemodialysis was started as soon as possible after completion of administration of the agents. No severe side effects were observed. After 4 courses of therapy, the patient achieved a partial response. More... »

PAGES

209-215

Journal

TITLE

Esophagus

ISSUE

3

VOLUME

8

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10388-011-0284-6

DOI

http://dx.doi.org/10.1007/s10388-011-0284-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005345272

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22593728


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