Carcinosarcoma of the esophagus producing granulocyte-colony stimulating factor: report of a case View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-09-18

AUTHORS

Keiichi Miyamoto, Shigeru Shibata, Hitoshi Kawasaki

ABSTRACT

A 51-year-old man was admitted to the hospital for dysphagia, pyrexia, and leukocytosis. The serum level of granulocyte-colony stimulating factor (G-CSF) was elevated. Barium esophagography and endoscopy revealed a polypoid tumor in the middle portion of the esophagus. After an esophagectomy, the leukocyte count and serum G-CSF level normalized. The pathological diagnosis was carcinosarcoma of the esophagus with two components: namely, squamous cell carcinoma and sarcoma. Moreover, cancer cells were positive for G-CSF antibody. These findings confirmed that the esophageal carcinosarcoma in this case was a G-CSF-producing tumor. Although a G-CSF-producing esophageal carcinosarcoma is very rare, this disease should be considered when a patient has symptoms such as leukocytosis and pyrexia without an associated infection. More... »

PAGES

171

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10388-008-0164-x

DOI

http://dx.doi.org/10.1007/s10388-008-0164-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020493274


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