Assessment of peripapillary choroidal thickness in primary open-angle glaucoma patients with choroidal vascular prominence View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-11

AUTHORS

Yong Ju Song, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park

ABSTRACT

PURPOSE: To investigate the relationship between peripapillary choroidal thickness (PCT) and choroidal vascular prominence (CVP) colocalized with retinal nerve fiber layer (RNFL) defect in primary open-angle glaucoma (POAG) eyes and to evaluate the relationship between PCT and POAG severity. METHODS: In this cross-sectional comparative study, 29 POAG patients with CVP on RNFL imaging (Group A), 70 POAG patients without CVP (Group B) and 63 healthy controls (Group C) were examined. Various factors including age, intraocular pressure (IOP), spherical equivalent (SE), axial length (AXL), central corneal thickness (CCT), peripapillary RNFL thickness, visual-field mean deviation (MD) and pattern standard deviation (PSD) were investigated. Also, PCT (average, clock-hour) was measured by swept-source optical coherence tomography. The differences in each of the factors were analyzed among the groups. RESULTS: There was no significant difference in age, IOP, SE, AXL or CCT among the three groups (P > 0.05). MD, PSD and RNFL thickness (RNFLT) in Groups A and B were lower than in Group C, but there was no difference between Groups A and B. There was a significant difference in adjusted PCT between Groups A and B (79.39 ± 6.56 vs. 115.87 ± 4.25, P < 0.001). Every adjusted clock-hour PCT in Group A was significantly thinner than in Group B. CONCLUSIONS: CVP in red-free RNFL images indicated severe thinning of PCT. Although PCT thinning was not related to glaucoma severity, CVP in red-free RNFL images should be observed as an indicator of PCT thinning, associated with POAG. More... »

PAGES

448-456

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10384-017-0535-8

DOI

http://dx.doi.org/10.1007/s10384-017-0535-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091839074

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28929241


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