Accommodative changes in human eye observed by Kitasato anterior segment optical coherence tomography View Full Text


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Article Info

DATE

2013-01

AUTHORS

Nobuyuki Satoh, Kimiya Shimizu, Atsushi Goto, Akihito Igarashi, Kazutaka Kamiya, Kohji Ohbayashi

ABSTRACT

PURPOSE: To study accommodative changes in the human lens using swept-source optical coherence tomography (Kitasato anterior segment OCT/KAs-OCT), which can image the whole anterior segment of the eye. METHODS: Thirty-five healthy subjects (mean age 41 years, range 13-79 years) were recruited. Using KAs-OCT, we measured the curvature of the anterior (ASC) and posterior surfaces (PSC), the thickness (LT) of the lens and the anterior chamber depth (ACD) in response to far (0.4 D) and near (10 D) accommodative stimuli. RESULTS: In response to accommodative stimuli (0.4/10 D), the mean values ± standard deviations were: radius of ASC, 9.72 ± 2.53/7.84 ± 1.85 mm (Wilcoxon ranked-sign test, p < 0.0001); radius of PSC, 5.06 ± 0.71/4.70 ± 0.76 mm (p = 0.0012); LT, 3.86 ± 0.77/4.00 ± 0.76 mm (p < 0.0001); ACD, 2.72 ± 0.61/2.61 ± 0.54 mm (p = 0.0002). The rate of accommodation-associated changes in ASC, LT, and ACD showed significant correlation with aging (Pearson correlation coefficient: r = -0.725, p < 0.0001; r = -0.626, p = 0.0001; r = -0.720, p < 0.0001, respectively), but there was no such correlation in PSC (r = -0.064, p = 0.401). CONCLUSION: The radius of ASC and PSC decreased with accommodation, and the rates of changes in ASC were larger than those in PSC. More... »

PAGES

113-119

References to SciGraph publications

  • 1855-03. Ueber die Accommodation des Auges in GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10384-012-0208-6

    DOI

    http://dx.doi.org/10.1007/s10384-012-0208-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1053487941

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23179763


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