Biomarkers of bone turnover in diagnosis and therapy of osteoporosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-08-14

AUTHORS

Christian Bieglmayer, Hans Peter Dimai, Rudolf Wolfgang Gasser, Stefan Kudlacek, Barbara Obermayer-Pietsch, Wolfgang Woloszczuk, Elisabeth Zwettler, Andrea Griesmacher

ABSTRACT

AimReasonable application of laboratory parameters in prevention, diagnosis, treatment and therapy monitoring of osteoporosis.Target groupsPhysicians from different specialist disciplines (general medicine, geriatrics, gynaecology, urology, internal medicine—especially endocrinology and metabolism, nephrology, laboratory medicine, rheumatology, nuclear medicine, orthopaedics, paediatrics, rehabilitation and physical medicine, radiology, social medicine, transplantation medicine, accident surgery), moreover social insurances, hospitals and self-help groups.BackgroundEvaluation of aetiology of bone disorders, widening of the therapeutic spectrum for diseases of bone and knowledge on biochemical markers of bone turnover. Improvements in judging the success of therapy and in monitoring the compliance of patients. Research perspectives.BasesScientific literature and guidelines, consensus meetings.RésuméBasic and specialized laboratory investigations are important in differentiation between primary and secondary osteoporosis for an adequate therapy. Biochemical markers of bone turnover are an additional aid in evaluation of individual fracture risk. These markers identify responders to bone therapy faster than surveillance of bone mineral density, which helps to improve patient’s compliance too. Characteristics, preanalytic precautions and applications are presented for selected markers of bone resorption and formation and for parameters regulating bone metabolism. More... »

PAGES

464-477

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  • Journal

    TITLE

    Wiener Medizinische Wochenschrift

    ISSUE

    21-22

    VOLUME

    162

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10354-012-0133-9

    DOI

    http://dx.doi.org/10.1007/s10354-012-0133-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1018623753

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22890523


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    362 grid-institutes:grid.11598.34 schema:alternateName Department of Endocrinology and Metabolism, Clinic for Internal Medicine, Medical University of Graz, Graz, Austria
    363 Laboratory for Endocrinology and Metabolism, Clinic for Internal Medicine Medical University of Graz, Graz, Austria
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    365 Laboratory for Endocrinology and Metabolism, Clinic for Internal Medicine Medical University of Graz, Graz, Austria
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    367 grid-institutes:grid.410706.4 schema:alternateName Central Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Innsbruck, Innsbruck, Austria
    368 schema:name Central Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Innsbruck, Innsbruck, Austria
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    370 grid-institutes:grid.411904.9 schema:alternateName Department of Laboratory Medicine Diagnostics, General Hospital of Vienna, Medical University of Vienna, 1090 Währinger Gürtel 18-20, Vienna, Austria
    371 schema:name Department of Laboratory Medicine Diagnostics, General Hospital of Vienna, Medical University of Vienna, 1090 Währinger Gürtel 18-20, Vienna, Austria
    372 ÖQUASTA (Austrian Society for Quality Assurance and Standardization of Medical Laboratory Tests), 1090 Hörlgasse 18/5, Vienna, Austria
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    374 grid-institutes:grid.491980.d schema:alternateName Ludwig Boltzmann Institute of Osteology, 1st Medical Department, Hanusch Hospital WGKK and AUVA Trauma Center Meidling, Vienna, Austria
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    377 grid-institutes:grid.5361.1 schema:alternateName Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria
    378 schema:name Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria
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