Sodium MRI of human articular cartilage of the wrist: a feasibility study on a clinical 3T MRI scanner View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2020-06-04

AUTHORS

Anja Müller-Lutz, Benedikt Kamp, Armin M. Nagel, Alexandra Ljimani, Daniel Abrar, Christoph Schleich, Lena Wollschläger, Sven Nebelung, Hans-Jörg Wittsack

ABSTRACT

ObjectiveTo measure sodium relaxation times and concentrations in human wrists on a clinical magnetic resonance imaging (MRI) scanner with a density-adapted radial sequence.Materials and methodsSodium MRI of human wrists was conducted on a 3T MR system using a dual-tuned 1H/23Na surface coil. We performed two studies with 10 volunteers each investigating either sodium T1 (study 1) or sodium T2* (study 2) relaxation times in the radiocarpal joint (RCJ) and midcarpal joint (MCJ). Sodium concentrations of both regions were determined.ResultsNo differences for transversal of longitudinal relaxation times were found between RCJ and MCJ (T2,s*(RCJ) = (0.9 ± 0.4) ms; T2,s*(MCJ) = (0.9 ± 0.3) ms; T2,l*(RCJ) = (14.9 ± 0.9) ms; T2,l*(MCJ) = (13.9 ± 1.1) ms; T1(RCJ) = (19.0 ± 2.4) ms; T1(MCJ) = (18.5 ± 2.1) ms). Sodium concentrations were (157.7 ± 28.4) mmol/l for study 1 and (159.8 ± 29.1) mmol/l for study 2 in the RCJ, and (172.7 ± 35.6) mmol/l for study 1 and (163.4 ± 26.3) mmol/l for study 2 in the MCJ.ConclusionWe successfully determined sodium relaxation times and concentrations of the human wrist on a 3T MRI scanner. More... »

PAGES

241-248

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10334-020-00856-2

DOI

http://dx.doi.org/10.1007/s10334-020-00856-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1128219671

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32500389


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