Comparison of B0 versus B0 and B1 field inhomogeneity correction for glycosaminoglycan chemical exchange saturation transfer imaging View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-05-14

AUTHORS

Anja Müller-Lutz, Alexandra Ljimani, Julia Stabinska, Moritz Zaiss, Johannes Boos, Hans-Jörg Wittsack, Christoph Schleich

ABSTRACT

PurposeThe study compares glycosaminoglycan chemical exchange saturation transfer (gagCEST) imaging of intervertebral discs corrected for solely B0 inhomogeneities or both B0 and B1 inhomogeneities.MethodsLumbar intervertebral discs of 20 volunteers were examined with T2-weighted and gagCEST imaging. Field inhomogeneity correction was performed with B0 correction only and with correction of both B0 and B1. GagCEST effects measured by the asymmetric magnetization transfer ratio (MTRasym) and signal-to-noise ratio (SNR) were compared between both methods.ResultsSignificant higher MTRasym and SNR values were obtained in the nucleus pulposus using B0 and B1 correction compared with B0-corrected gagCEST. The GagCEST effect was significantly different in the nucleus pulposus compared with the annulus fibrosus for both methods.ConclusionThe B0 and B1 field inhomogeneity correction method leads to an improved quality of gagCEST imaging in IVDs compared with only B0 correction. More... »

PAGES

645-651

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10334-018-0689-5

DOI

http://dx.doi.org/10.1007/s10334-018-0689-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1103973817

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29761413


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