Ontology type: schema:ScholarlyArticle
2004-10
AUTHORSJohannes T. Heverhagen, Horst K. Hahn, Michael Wegmann, Udo Herz, Chastity D. Shaffer Whitaker, Volker Matschl, Heiko Alfke
ABSTRACTSmall animal models are widely used to study various pathologies. Magnetic resonance imaging (MRI) allows investigation of these animals in a non-invasive way. Therefore, the aim of our study was to develop and evaluate a low-cost approach to measure lung volumes in small animal MRI using a clinical scanner and a specially designed RF coil. Five mice (three of an established emphysema model and two controls) were investigated in a 1.0-T clinical scanner using a specially built small animal saddle coil and three different three-dimensional sequences; overall imaging time was approximately 16 min. Lung volumes were calculated from these images using an interactive watershed transform algorithm for semi-automatic image segmentation. The gold standard for the volume measurement was water displacement after surgical explantation. MRI measured volumes correlated significantly with ex vivo measurements on the explanted lungs (r = 0.99 to 0.89; p < 0.05). Mean lung volume in emphysema model mice was larger than in controls. High-resolution, small animal MRI using a clinical scanner is feasible for volumetric analysis and provides an alternative to a dedicated small animal scanner. More... »
PAGES80-85
http://scigraph.springernature.com/pub.10.1007/s10334-004-0053-9
DOIhttp://dx.doi.org/10.1007/s10334-004-0053-9
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1036977953
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/15480944
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0903",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biomedical Engineering",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/09",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Engineering",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Disease Models, Animal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Emphysema",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Equipment Design",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Equipment Failure Analysis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lung Volume Measurements",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mice",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mice, Inbred C57BL",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Reproducibility of Results",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Sensitivity and Specificity",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Transducers",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Philipp University of Marburg",
"id": "https://www.grid.ac/institutes/grid.10253.35",
"name": [
"Department of Diagnostic Radiology, Philipps University, 35033, Marburg, Germany"
],
"type": "Organization"
},
"familyName": "Heverhagen",
"givenName": "Johannes T.",
"id": "sg:person.01227341013.74",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227341013.74"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The Ohio State University",
"id": "https://www.grid.ac/institutes/grid.261331.4",
"name": [
"Department of Radiology, The Ohio State University, 1654 Upham Drive, 647 Means Hall, 43210, Columbus, OH, USA"
],
"type": "Organization"
},
"familyName": "Hahn",
"givenName": "Horst K.",
"id": "sg:person.0764213163.20",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764213163.20"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"MeVis-Center for Medical Diagnostic Systems and Visualization, 28359, Bremen, Germany"
],
"type": "Organization"
},
"familyName": "Wegmann",
"givenName": "Michael",
"id": "sg:person.01057073775.47",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057073775.47"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"MeVis-Center for Medical Diagnostic Systems and Visualization, 28359, Bremen, Germany"
],
"type": "Organization"
},
"familyName": "Herz",
"givenName": "Udo",
"id": "sg:person.0675412673.89",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675412673.89"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The Ohio State University",
"id": "https://www.grid.ac/institutes/grid.261331.4",
"name": [
"Department of Radiology, The Ohio State University, 1654 Upham Drive, 647 Means Hall, 43210, Columbus, OH, USA"
],
"type": "Organization"
},
"familyName": "Whitaker",
"givenName": "Chastity D. Shaffer",
"id": "sg:person.01005306076.43",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005306076.43"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Siemens (Germany)",
"id": "https://www.grid.ac/institutes/grid.5406.7",
"name": [
"Department of Clinical Chemistry, Philipps University, 35033, Marburg, Germany",
"Siemens Medical Solutions, 91052, Erlangen, Germany"
],
"type": "Organization"
},
"familyName": "Matschl",
"givenName": "Volker",
"id": "sg:person.01371621225.70",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371621225.70"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Philipp University of Marburg",
"id": "https://www.grid.ac/institutes/grid.10253.35",
"name": [
"Department of Diagnostic Radiology, Philipps University, 35033, Marburg, Germany"
],
"type": "Organization"
},
"familyName": "Alfke",
"givenName": "Heiko",
"id": "sg:person.0732730137.65",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732730137.65"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/bf02678487",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005088893",
"https://doi.org/10.1007/bf02678487"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02678487",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005088893",
"https://doi.org/10.1007/bf02678487"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1023/a:1024241905888",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005202807",
"https://doi.org/10.1023/a:1024241905888"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1038/sj.neo.7900079",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006774337"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1359/jbmr.2000.15.12.2451",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010688912"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/mrm.1910320215",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013616532"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0344-0338(99)80052-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014162944"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1117/12.481097",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016849603"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00259-001-0683-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018614151",
"https://doi.org/10.1007/s00259-001-0683-3"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0165-0270(00)00172-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018952728"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0959-8049(02)00394-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022633040"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0959-8049(02)00394-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022633040"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002142-200108000-00006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025119996"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002142-200108000-00006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025119996"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ijc.10913",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026543885"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/mrm.10326",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029123315"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0361-9230(93)90017-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033455071"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0361-9230(93)90017-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033455071"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/ilar.42.3.248",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034242143"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0730-725x(97)00273-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037032007"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1097/00004647-200205000-00007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040107624",
"https://doi.org/10.1097/00004647-200205000-00007"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00004647-200205000-00007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040107624"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0301-0082(02)00020-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044743669"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.bioeng.1.1.611",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044979311"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1352-8661(00)00105-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054696616"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1352-8661(01)00147-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054696697"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1109/6.625252",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1061196287"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3109/10976649909088333",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070985776"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/physiolgenomics.2001.4.3.215",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074751858"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083347331",
"type": "CreativeWork"
}
],
"datePublished": "2004-10",
"datePublishedReg": "2004-10-01",
"description": "Small animal models are widely used to study various pathologies. Magnetic resonance imaging (MRI) allows investigation of these animals in a non-invasive way. Therefore, the aim of our study was to develop and evaluate a low-cost approach to measure lung volumes in small animal MRI using a clinical scanner and a specially designed RF coil. Five mice (three of an established emphysema model and two controls) were investigated in a 1.0-T clinical scanner using a specially built small animal saddle coil and three different three-dimensional sequences; overall imaging time was approximately 16 min. Lung volumes were calculated from these images using an interactive watershed transform algorithm for semi-automatic image segmentation. The gold standard for the volume measurement was water displacement after surgical explantation. MRI measured volumes correlated significantly with ex vivo measurements on the explanted lungs (r = 0.99 to 0.89; p < 0.05). Mean lung volume in emphysema model mice was larger than in controls. High-resolution, small animal MRI using a clinical scanner is feasible for volumetric analysis and provides an alternative to a dedicated small animal scanner.",
"genre": "research_article",
"id": "sg:pub.10.1007/s10334-004-0053-9",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1104145",
"issn": [
"0968-5243",
"1352-8661"
],
"name": "Magnetic Resonance Materials in Physics, Biology and Medicine",
"type": "Periodical"
},
{
"issueNumber": "2",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "17"
}
],
"name": "Volumetric analysis of mice lungs in a clinical magnetic resonance imaging scanner",
"pagination": "80-85",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"b026561bf79c0583a9721aeec11159e770b4953da6bfe99fac373201bb53f7e6"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"15480944"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9310752"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s10334-004-0053-9"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1036977953"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s10334-004-0053-9",
"https://app.dimensions.ai/details/publication/pub.1036977953"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T18:24",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000533.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007%2Fs10334-004-0053-9"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10334-004-0053-9'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10334-004-0053-9'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10334-004-0053-9'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10334-004-0053-9'
This table displays all metadata directly associated to this object as RDF triples.
247 TRIPLES
21 PREDICATES
66 URIs
32 LITERALS
20 BLANK NODES