Ferritin involved in the tumor development View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-11

AUTHORS

Wenqing Wei

ABSTRACT

Ferritin is a kind of glycoprotein synthesized by the liver. Being the main form of stored iron in the body, it plays an important role in the iron balance. When the iron level in the body increases, ferritin can intake and storage the iron avoiding the cytotoxicity caused by the high level of intracellular iron; when body needs more iron, ferritin can release iron at any time. Recent studies have found that tumor tissue can synthesize and secrete ferritin. Ferritin levels increase in liver cancer, lung cancer, pancreatic cancer, breast cancer, leukemia and other malignancies. In this paper, we reviewed the relationship between the changed ferritin and the malignancy disease. More... »

PAGES

551-554

References to SciGraph publications

  • 2010-04-13. Role of ferritin alterations in human breast cancer cells in BREAST CANCER RESEARCH AND TREATMENT
  • 2008-09-30. Vasculogenic mimicry formation in hepatocellular carcinoma in THE CHINESE-GERMAN JOURNAL OF CLINICAL ONCOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10330-013-1237-4

    DOI

    http://dx.doi.org/10.1007/s10330-013-1237-4

    DIMENSIONS

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