Radiofrequency induction on sodium/iodide symporter expression of thyroid cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-11

AUTHORS

Youxin Tian, Qinjiang Liu, Yaqiong Ni

ABSTRACT

ObjectiveThe aim of this study was to investigate the effects of radiofrequency treatment on sodium/iodide symporter expression of thyroid cancer cells.MethodsIn 29 thyroid cancer patients with low or no expression of soda \ iodide symporter, the radio frequency combined 131I therapy was used, the whole-body scintigraphy and serum Ig were detected before and after the radiofrequency treatment.ResultsThe whole-body scintigraphy showed that 4 cases (4/29) before radiofrequency treatment had positive iodine uptake, 19 cases (19/29) two weeks after radiofrequency treatment had the positive iodine uptake, 12 cases (12/29) four weeks after radiofrequency treatment had the positive iodine uptake. Four weeks after radiofrequency treatment, 5 cases had increased serum Ig levels, 17 cases had decreased serum Ig levels, 7 cases showed no change. 25 cases (25/29) were effective, 15 cases (15/29) were cured.ConclusionThe radiofrequency induced the non-expressed the sodium/iodide symporter of thyroid cancer cells regain the iodine intake ability, it improved the clinical efficacy of 131I therapy in dedifferentiated thyroid cancer. More... »

PAGES

516-520

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10330-013-1224-9

DOI

http://dx.doi.org/10.1007/s10330-013-1224-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012621505


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