A dosimetric comparison between 3D-conformal radiation therapy and intensity modulated radiation therapy plans in the treatment of posterior fossa boost ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-11

AUTHORS

I. Saad El Din, H. Abd El AAl, W. Makaar, K. Mashhour, D. El Beih, W. Hashem

ABSTRACT

ObjectiveThe work is a comparative study between two modalities of radiation therapy, the aim of which is to compare 3D conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) in treating posterior fossa boost in children with high risk medulloblastoma; dosimetrically evaluating and comparing both techniques as regard target coverage and doses to organs at risk (OAR).MethodsTwenty patients with high risk medulloblastoma were treated by 3D-CRT technique. A dosimetric comparison was done by performing two plans for the posterior fossa boost, 3D-CRT and IMRT plans, for the same patient using Eclipse planning system (version 8.6).ResultsIMRT had a better conformity index compared to 3D-CRT plans (P value of 0.000). As for the dose homogeneity it was also better in the IMRT plans, yet it hasn’t reached the statistical significant value. Also, doses received by the cochleae, brainstem and spinal cord were significantly less in the IMRT plans than those of 3D-CRT (P value < 0.05).ConclusionIMRT technique was clearly able to improve conformity and homogeneity index, spare the cochleae, reduce dose to the brainstem and spinal cord in comparison to 3D-CRT technique. More... »

PAGES

540-545

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10330-013-1211-1

DOI

http://dx.doi.org/10.1007/s10330-013-1211-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041678102


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