Prognosis in epithelial ovarian cancer: Clinical analysis of 287 pelvic and para-aortic lymphadenectomy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-10

AUTHORS

Xiaoyun Yang, Minmin Hou, Kaixuan Yang, Hongjing Wang, Zhilan Peng, Zeyi Cao, Mingrong Xi

ABSTRACT

To evaluate the relationship between the pelvic and para-aortic lymphadenectomy and the prognosis of epithelial ovarian cancer. 287 patients suffering from primary epithelial ovarian cancer from 1995 to 2005 were analyzed retrospectively. The 3-, 5-, 10-year survival with systematic lymphadenectomy (SL) were slightly higher than those without SL, but there were no statistically significance (P > 0.05). The 3-, 5-, 10-year survival of clinical stages without SL were lower than those with SL, but there were no significant difference either (P > 0.05). The 3-,5-, and 10-year survival rates with SL were higher than those without SL with no statistically differences (P > 0.05) among the subgroups such as absent, ≤ 2 cm and > 2 cm residual tumor. The survival rates of the groups without residual tumor and the group with ≤ 2 cm residual tumor were significantly higher than that of > 2 cm (P < 0.005). On multivariate analysis, patient staging (P = 0.01) and size of residual disease after primary cytoreductive surgery (P < 0.001 and = 0.002, respectively) retained prognostic significance. SL was not proved to be an independent prognostic factor (P = 0.69). Systematic pelvic and paraaortic lymphadenectomy can not improve and prolong the survival time significantly. More... »

PAGES

492-496

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10330-007-0092-6

DOI

http://dx.doi.org/10.1007/s10330-007-0092-6

DIMENSIONS

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136 Department of Pathology, West China Second University Hospital, Sichuan University, 610041, Chengdu, China
137 rdf:type schema:Organization
 




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