Antimicrobial activity on glass materials subject to disinfectant xerogel coating View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-12-09

AUTHORS

G. J. Copello, S. Teves, J. Degrossi, M. D’Aquino, M. F. Desimone, L. E. Diaz

ABSTRACT

The antimicrobial compound dodecyl-di(aminoethyl)-glycine was immobilized in a silicon oxide xerogel matrix and used for glass surface coating. Coated glasses were tested for surface antimicrobial activity. The utilization of tetraethoxysilane (TEOS) as a silicon oxide polymer precursor, using the dip-coating process, allowed for the generation of transparent thin films over glass surfaces. Different concentrations of the antimicrobial compound were used to generate the coatings. The presence of dodecyl-di(aminoethyl)-glycine on coated and uncoated slides was analyzed by FT-IR spectra. Coated glass slides were exposed to suspensions of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus for 24 h. Surface contamination was evaluated by the microbial plate count technique. When antimicrobial-coated glasses were compared with antimicrobial-free coated glasses, the former showed greater than 99% reduction of colony-forming units (cfu) for E. coli and P. aeruginosa, when 1% of antimicrobial was present in the coating solution. The same percentage of reduction for S. aureus was achieved when 1.5% of the antimicrobial was present in the coating solution. In a direct inhibition test on agar plates, no inhibitory zone was observed, indicating that the antimicrobial did not diffuse into the media. More... »

PAGES

343-348

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10295-005-0066-z

DOI

http://dx.doi.org/10.1007/s10295-005-0066-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029001410

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16341729


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