Dipeptidyl peptidase-4(DPP-4) inhibitors: promising new agents for autoimmune diabetes View Full Text


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Article Info

DATE

2018-11

AUTHORS

Xia Wang, Peilin Zheng, Gan Huang, Lin Yang, Zhiguang Zhou

ABSTRACT

Dipeptidyl peptidase-4 (DPP-4) inhibitors constitute a novel class of anti-diabetic agents confirmed to improve glycemic control and preserve β-cell function in type 2 diabetes. Three major large-scale studies, EXAMINE, SAVOR-TIMI 53, and TECOS, have confirmed the cardiovascular safety profile of DPP-4 inhibitors. Based on these results, DPP-4 inhibitors have gained widespread use in type 2 diabetes treatment. It is currently unknown, however, whether DPP-4 inhibitors have similar therapeutic efficacy against autoimmune diabetes. Several in vitro and in vivo studies have addressed this issue, but the results remain controversial. In this review, we summarize experimental findings and preliminary clinical trial results, and identify potentially effective immune modulation targets of DPP-4 inhibitors for autoimmune diabetes. More... »

PAGES

473-480

References to SciGraph publications

  • 2014-12. Dipeptidyl peptidase-4 inhibitors do not increase the risk of cardiovascular events in type 2 diabetes: a cohort study in ACTA DIABETOLOGICA
  • 2017-10. Possible Long-Term Efficacy of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, for Slowly Progressive Type 1 Diabetes (SPIDDM) in the Stage of Non-Insulin-Dependency: An Open-Label Randomized Controlled Pilot Trial (SPAN-S) in DIABETES THERAPY
  • 2012-12. Treatment of autoimmune diabetes in NOD mice by Toll-like receptor 2 tolerance in conjunction with dipeptidyl peptidase 4 inhibition in DIABETOLOGIA
  • 2011-07. Pharmacology of Dipeptidyl Peptidase-4 Inhibitors in DRUGS
  • 2017-05. DPP4 inhibitors and cardiovascular outcomes: safety on heart failure in HEART FAILURE REVIEWS
  • 2012-10. Insulin autoantibody could help to screen latent autoimmune diabetes in adults in phenotypic type 2 diabetes mellitus in Chinese in ACTA DIABETOLOGICA
  • 2012-06. TGF-β and IL-23 gene expression in unstimulated PBMCs of patients with diabetes in ENDOCRINE
  • 2016-09. Tetraspanin 7 autoantibodies in type 1 diabetes in DIABETOLOGIA
  • 2005-04. IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes (UKPDS 71) in DIABETOLOGIA
  • 2015-11. TAK1 inhibition prevents the development of autoimmune diabetes in NOD mice in SCIENTIFIC REPORTS
  • 2014-10. Elevated Levels of Serum IL-12 and IL-18 are Associated with Lower Frequencies of CD4+CD25highFOXP3+ Regulatory T cells in Young Patients with Type 1 Diabetes in INFLAMMATION
  • 2017-10. Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it? in DIABETOLOGIA
  • 2009-08. Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor restores normoglycaemia in non-obese diabetic mice in DIABETOLOGIA
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10238-018-0519-0

    DOI

    http://dx.doi.org/10.1007/s10238-018-0519-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1105642773

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30022375


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