From single muscle fiber to whole muscle mechanics: a finite element model of a muscle bundle with fast and slow ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-06-05

AUTHORS

Lorenzo Marcucci, Carlo Reggiani, Arturo N. Natali, Piero G. Pavan

ABSTRACT

Muscles exhibit highly complex, multi-scale architecture with thousands of muscle fibers, each with different properties, interacting with each other and surrounding connective structures. Consequently, the results of single-fiber experiments are scarcely linked to the macroscopic or whole muscle behavior. This is especially true for human muscles where it would be important to understand of how skeletal muscles disorders affect patients’ life. In this work, we developed a mathematical model to study how fast and slow muscle fibers, well characterized in single-fiber experiments, work and generate together force and displacement in muscle bundles. We characterized the parameters of a Hill-type model, using experimental data on fast and slow single human muscle fibers, and comparing experimental data with numerical simulations obtained from finite element (FE) models of single fibers. Then, we developed a FE model of a bundle of 19 fibers, based on an immunohistochemically stained cross section of human diaphragm and including the corresponding properties of each slow or fast fiber. Simulations of isotonic contractions of the bundle model allowed the generation of its apparent force–velocity relationship. Although close to the average of the force–velocity curves of fast and slow fibers, the bundle curve deviates substantially toward the fast fibers at low loads. We believe that the present model and the characterization of the force–velocity curve of a fiber bundle represents the starting point to link the single-fiber properties to those of whole muscle with FE application in phenomenological models of human muscles. More... »

PAGES

1833-1843

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10237-017-0922-6

DOI

http://dx.doi.org/10.1007/s10237-017-0922-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1085862644

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28584973


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/09", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0903", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biomedical Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0913", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Mechanical Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomechanical Phenomena", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Computer Simulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Finite Element Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Biological", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Contraction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Fibers, Fast-Twitch", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Fibers, Slow-Twitch", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Numerical Analysis, Computer-Assisted", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Biomedical Sciences, University of Padova, Via Marzolo 3, 35131, Padua, Italy", 
            "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Marcucci", 
        "givenName": "Lorenzo", 
        "id": "sg:person.016523732771.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016523732771.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Biomedical Sciences, University of Padova, Via Marzolo 3, 35131, Padua, Italy", 
            "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reggiani", 
        "givenName": "Carlo", 
        "id": "sg:person.01050447244.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050447244.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Industrial Engineering, University of Padova, Via Venezia 1, 35131, Padua, Italy", 
            "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Natali", 
        "givenName": "Arturo N.", 
        "id": "sg:person.01023027206.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023027206.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy", 
          "id": "http://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Industrial Engineering, University of Padova, Via Venezia 1, 35131, Padua, Italy", 
            "Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pavan", 
        "givenName": "Piero G.", 
        "id": "sg:person.015610706160.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015610706160.57"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s10439-012-0531-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038006378", 
          "https://doi.org/10.1007/s10439-012-0531-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.2152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049776797", 
          "https://doi.org/10.1038/nmeth.2152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/372515a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036881226", 
          "https://doi.org/10.1038/372515a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/16403", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000451350", 
          "https://doi.org/10.1038/16403"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-06-05", 
    "datePublishedReg": "2017-06-05", 
    "description": "Muscles exhibit highly complex, multi-scale architecture with thousands of muscle fibers, each with different properties, interacting with each other and surrounding connective structures. Consequently, the results of single-fiber experiments are scarcely linked to the macroscopic or whole muscle behavior. This is especially true for human muscles where it would be important to understand of how skeletal muscles disorders affect patients\u2019 life. In this work, we developed a mathematical model to study how fast and slow muscle fibers, well characterized in single-fiber experiments, work and generate together force and displacement in muscle bundles. We characterized the parameters of a Hill-type model, using experimental data on fast and slow single human muscle fibers, and comparing experimental data with numerical simulations obtained from finite element (FE) models of single fibers. Then, we developed a FE model of a bundle of 19 fibers, based on an immunohistochemically stained cross section of human diaphragm and including the corresponding properties of each slow or fast fiber. Simulations of isotonic contractions of the bundle model allowed the generation of its apparent force\u2013velocity relationship. Although close to the average of the force\u2013velocity curves of fast and slow fibers, the bundle curve deviates substantially toward the fast fibers at low loads. We believe that the present model and the characterization of the force\u2013velocity curve of a fiber bundle represents the starting point to link the single-fiber properties to those of whole muscle with FE application in phenomenological models of human muscles.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s10237-017-0922-6", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3799434", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1030355", 
        "issn": [
          "1617-7959", 
          "1617-7940"
        ], 
        "name": "Biomechanics and Modeling in Mechanobiology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "keywords": [
      "mathematical model", 
      "single-fiber experiments", 
      "experimental data", 
      "whole muscle behaviour", 
      "finite element model", 
      "numerical simulations", 
      "phenomenological model", 
      "Hill-type model", 
      "corresponding properties", 
      "present model", 
      "bundle model", 
      "element model", 
      "connective structures", 
      "force-velocity curve", 
      "single fiber properties", 
      "simulations", 
      "model", 
      "cross sections", 
      "different properties", 
      "mechanics", 
      "starting point", 
      "properties", 
      "fiber bundles", 
      "force-velocity relationship", 
      "curves", 
      "bundles", 
      "FE model", 
      "Fe application", 
      "parameters", 
      "muscle mechanics", 
      "point", 
      "muscle behavior", 
      "applications", 
      "experiments", 
      "force", 
      "displacement", 
      "structure", 
      "data", 
      "single human muscle fibers", 
      "behavior", 
      "work", 
      "results", 
      "thousands", 
      "average", 
      "generation", 
      "sections", 
      "load", 
      "characterization", 
      "multi-scale architecture", 
      "architecture", 
      "human diaphragm", 
      "isotonic contractions", 
      "fibers", 
      "single fiber", 
      "contraction", 
      "relationship", 
      "human muscle", 
      "low load", 
      "whole muscle", 
      "diaphragm", 
      "human muscle fibers", 
      "slow muscle fibers", 
      "fast fibers", 
      "single muscle fibers", 
      "life", 
      "muscle fibers", 
      "disorders", 
      "muscle bundles", 
      "muscle", 
      "patient's life", 
      "skeletal muscle disorders", 
      "slow fibers", 
      "muscle disorders"
    ], 
    "name": "From single muscle fiber to whole muscle mechanics: a finite element model of a muscle bundle with fast and slow fibers", 
    "pagination": "1833-1843", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1085862644"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10237-017-0922-6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28584973"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10237-017-0922-6", 
      "https://app.dimensions.ai/details/publication/pub.1085862644"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:43", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_754.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s10237-017-0922-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10237-017-0922-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10237-017-0922-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10237-017-0922-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10237-017-0922-6'


 

This table displays all metadata directly associated to this object as RDF triples.

211 TRIPLES      21 PREDICATES      111 URIs      98 LITERALS      15 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10237-017-0922-6 schema:about N0b60b1a8287343628917dba9dd7a823a
2 N3a4fac762b8342dc8b3bbf9ec2f5c513
3 N4244b8636cf84bdbb321d74ecabc15cc
4 N57fe29b1223b494baadf13b320ffdfdc
5 N864bcb2e60e243268a32f82571fcf345
6 N9ec1e07a072740a7824339d5590fd551
7 Ncc061e5683f74752b7ee5ba9c8536e98
8 Nfb806c2dba4f40d6a25d7734f42ce84d
9 anzsrc-for:09
10 anzsrc-for:0903
11 anzsrc-for:0913
12 schema:author N64d7ca879318451dbb38f7369ecbd94b
13 schema:citation sg:pub.10.1007/s10439-012-0531-6
14 sg:pub.10.1038/16403
15 sg:pub.10.1038/372515a0
16 sg:pub.10.1038/nmeth.2152
17 schema:datePublished 2017-06-05
18 schema:datePublishedReg 2017-06-05
19 schema:description Muscles exhibit highly complex, multi-scale architecture with thousands of muscle fibers, each with different properties, interacting with each other and surrounding connective structures. Consequently, the results of single-fiber experiments are scarcely linked to the macroscopic or whole muscle behavior. This is especially true for human muscles where it would be important to understand of how skeletal muscles disorders affect patients’ life. In this work, we developed a mathematical model to study how fast and slow muscle fibers, well characterized in single-fiber experiments, work and generate together force and displacement in muscle bundles. We characterized the parameters of a Hill-type model, using experimental data on fast and slow single human muscle fibers, and comparing experimental data with numerical simulations obtained from finite element (FE) models of single fibers. Then, we developed a FE model of a bundle of 19 fibers, based on an immunohistochemically stained cross section of human diaphragm and including the corresponding properties of each slow or fast fiber. Simulations of isotonic contractions of the bundle model allowed the generation of its apparent force–velocity relationship. Although close to the average of the force–velocity curves of fast and slow fibers, the bundle curve deviates substantially toward the fast fibers at low loads. We believe that the present model and the characterization of the force–velocity curve of a fiber bundle represents the starting point to link the single-fiber properties to those of whole muscle with FE application in phenomenological models of human muscles.
20 schema:genre article
21 schema:isAccessibleForFree false
22 schema:isPartOf N1186767fcd954feaba7d6c299e4890b6
23 Ncbbccdffe7e9425ba89b6901a2ee14db
24 sg:journal.1030355
25 schema:keywords FE model
26 Fe application
27 Hill-type model
28 applications
29 architecture
30 average
31 behavior
32 bundle model
33 bundles
34 characterization
35 connective structures
36 contraction
37 corresponding properties
38 cross sections
39 curves
40 data
41 diaphragm
42 different properties
43 disorders
44 displacement
45 element model
46 experimental data
47 experiments
48 fast fibers
49 fiber bundles
50 fibers
51 finite element model
52 force
53 force-velocity curve
54 force-velocity relationship
55 generation
56 human diaphragm
57 human muscle
58 human muscle fibers
59 isotonic contractions
60 life
61 load
62 low load
63 mathematical model
64 mechanics
65 model
66 multi-scale architecture
67 muscle
68 muscle behavior
69 muscle bundles
70 muscle disorders
71 muscle fibers
72 muscle mechanics
73 numerical simulations
74 parameters
75 patient's life
76 phenomenological model
77 point
78 present model
79 properties
80 relationship
81 results
82 sections
83 simulations
84 single fiber
85 single fiber properties
86 single human muscle fibers
87 single muscle fibers
88 single-fiber experiments
89 skeletal muscle disorders
90 slow fibers
91 slow muscle fibers
92 starting point
93 structure
94 thousands
95 whole muscle
96 whole muscle behaviour
97 work
98 schema:name From single muscle fiber to whole muscle mechanics: a finite element model of a muscle bundle with fast and slow fibers
99 schema:pagination 1833-1843
100 schema:productId N7384f9c95ef9423fbb018acab285226c
101 Nf6a5bbcb1a984e38b47f91376748d1c3
102 Nfb7f93d2691f4ee7b3b4358876891eab
103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085862644
104 https://doi.org/10.1007/s10237-017-0922-6
105 schema:sdDatePublished 2022-10-01T06:43
106 schema:sdLicense https://scigraph.springernature.com/explorer/license/
107 schema:sdPublisher Nf92aef49b7af4ee2a51e2174cce34d1c
108 schema:url https://doi.org/10.1007/s10237-017-0922-6
109 sgo:license sg:explorer/license/
110 sgo:sdDataset articles
111 rdf:type schema:ScholarlyArticle
112 N082ff996415543da9570d6649fb40c5f rdf:first sg:person.01050447244.76
113 rdf:rest N08b92f0043e34b5a9c37babd44d190f1
114 N08b92f0043e34b5a9c37babd44d190f1 rdf:first sg:person.01023027206.95
115 rdf:rest Nc3b8ab93d9964259ae551472eefce42e
116 N0b60b1a8287343628917dba9dd7a823a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Numerical Analysis, Computer-Assisted
118 rdf:type schema:DefinedTerm
119 N1186767fcd954feaba7d6c299e4890b6 schema:issueNumber 6
120 rdf:type schema:PublicationIssue
121 N3a4fac762b8342dc8b3bbf9ec2f5c513 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Biomechanical Phenomena
123 rdf:type schema:DefinedTerm
124 N4244b8636cf84bdbb321d74ecabc15cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Finite Element Analysis
126 rdf:type schema:DefinedTerm
127 N57fe29b1223b494baadf13b320ffdfdc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Models, Biological
129 rdf:type schema:DefinedTerm
130 N64d7ca879318451dbb38f7369ecbd94b rdf:first sg:person.016523732771.39
131 rdf:rest N082ff996415543da9570d6649fb40c5f
132 N7384f9c95ef9423fbb018acab285226c schema:name pubmed_id
133 schema:value 28584973
134 rdf:type schema:PropertyValue
135 N864bcb2e60e243268a32f82571fcf345 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Muscle Contraction
137 rdf:type schema:DefinedTerm
138 N9ec1e07a072740a7824339d5590fd551 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Muscle Fibers, Fast-Twitch
140 rdf:type schema:DefinedTerm
141 Nc3b8ab93d9964259ae551472eefce42e rdf:first sg:person.015610706160.57
142 rdf:rest rdf:nil
143 Ncbbccdffe7e9425ba89b6901a2ee14db schema:volumeNumber 16
144 rdf:type schema:PublicationVolume
145 Ncc061e5683f74752b7ee5ba9c8536e98 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Computer Simulation
147 rdf:type schema:DefinedTerm
148 Nf6a5bbcb1a984e38b47f91376748d1c3 schema:name doi
149 schema:value 10.1007/s10237-017-0922-6
150 rdf:type schema:PropertyValue
151 Nf92aef49b7af4ee2a51e2174cce34d1c schema:name Springer Nature - SN SciGraph project
152 rdf:type schema:Organization
153 Nfb7f93d2691f4ee7b3b4358876891eab schema:name dimensions_id
154 schema:value pub.1085862644
155 rdf:type schema:PropertyValue
156 Nfb806c2dba4f40d6a25d7734f42ce84d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Muscle Fibers, Slow-Twitch
158 rdf:type schema:DefinedTerm
159 anzsrc-for:09 schema:inDefinedTermSet anzsrc-for:
160 schema:name Engineering
161 rdf:type schema:DefinedTerm
162 anzsrc-for:0903 schema:inDefinedTermSet anzsrc-for:
163 schema:name Biomedical Engineering
164 rdf:type schema:DefinedTerm
165 anzsrc-for:0913 schema:inDefinedTermSet anzsrc-for:
166 schema:name Mechanical Engineering
167 rdf:type schema:DefinedTerm
168 sg:grant.3799434 http://pending.schema.org/fundedItem sg:pub.10.1007/s10237-017-0922-6
169 rdf:type schema:MonetaryGrant
170 sg:journal.1030355 schema:issn 1617-7940
171 1617-7959
172 schema:name Biomechanics and Modeling in Mechanobiology
173 schema:publisher Springer Nature
174 rdf:type schema:Periodical
175 sg:person.01023027206.95 schema:affiliation grid-institutes:grid.5608.b
176 schema:familyName Natali
177 schema:givenName Arturo N.
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023027206.95
179 rdf:type schema:Person
180 sg:person.01050447244.76 schema:affiliation grid-institutes:grid.5608.b
181 schema:familyName Reggiani
182 schema:givenName Carlo
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050447244.76
184 rdf:type schema:Person
185 sg:person.015610706160.57 schema:affiliation grid-institutes:grid.5608.b
186 schema:familyName Pavan
187 schema:givenName Piero G.
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015610706160.57
189 rdf:type schema:Person
190 sg:person.016523732771.39 schema:affiliation grid-institutes:grid.5608.b
191 schema:familyName Marcucci
192 schema:givenName Lorenzo
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016523732771.39
194 rdf:type schema:Person
195 sg:pub.10.1007/s10439-012-0531-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038006378
196 https://doi.org/10.1007/s10439-012-0531-6
197 rdf:type schema:CreativeWork
198 sg:pub.10.1038/16403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000451350
199 https://doi.org/10.1038/16403
200 rdf:type schema:CreativeWork
201 sg:pub.10.1038/372515a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036881226
202 https://doi.org/10.1038/372515a0
203 rdf:type schema:CreativeWork
204 sg:pub.10.1038/nmeth.2152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049776797
205 https://doi.org/10.1038/nmeth.2152
206 rdf:type schema:CreativeWork
207 grid-institutes:grid.5608.b schema:alternateName Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy
208 schema:name Centre for Mechanics of Biological Materials, University of Padova, Via Marzolo 9, 35131, Padua, Italy
209 Department of Biomedical Sciences, University of Padova, Via Marzolo 3, 35131, Padua, Italy
210 Department of Industrial Engineering, University of Padova, Via Venezia 1, 35131, Padua, Italy
211 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...