A case of refractory cutaneous polyarteritis nodosa in a patient with hepatitis B carrier status successfully treated with tumor necrosis ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-09-13

AUTHORS

Takeshi Zoshima, Masami Matsumura, Yasunori Suzuki, Yasushi Kakuchi, Ichiro Mizushima, Hiroshi Fujii, Kazunori Yamada, Masakazu Yamagishi, Mitsuhiro Kawano

ABSTRACT

We describe a patient with refractory cutaneous polyarteritis nodosa (CPAN) with hepatitis B virus (HBV) carrier status who was successfully treated with tumor necrosis factor alpha (TNF-α) blockade, using etanercept, and we review 5 similar cases. We administered etanercept because of the occurrence of repeated flares despite aggressive therapy. C-reactive protein normalization; prednisolone dose-sparing; and absence of any adverse events, including HBV reactivation with nucleotide analogue administration, or renal dysfunction, have been achieved for 8 months. TNF-α blockade should be considered for intractable CPAN. More... »

PAGES

1029-1033

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10165-012-0732-8

DOI

http://dx.doi.org/10.1007/s10165-012-0732-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024385324

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22972013


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