Hydralazine-induced autoimmune disease: comparison to idiopathic lupus and ANCA-positive vasculitis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-06

AUTHORS

Naoto Yokogawa, Frederick B. Vivino

ABSTRACT

We report two cases of hydralazine-induced vasculitis with rare complications: pulmonary renal syndrome and digital gangrene. We also review 68 published cases of hydralazine-induced vasculitis. Hydralazine-induced vasculitis mimics idiopathic antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis. However, it also produces other autoantibodies, such as antinuclear antibodies, antihistone antibodies, anti-dsDNA antibodies, and antiphospholipid antibodies. Patients with hydralazine-induced vasculitis typically have a more severe course than those with hydralazine-induced lupus, predominantly due to renal vasculitis, and require a more aggressive treatment. More... »

PAGES

338

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10165-009-0168-y

DOI

http://dx.doi.org/10.1007/s10165-009-0168-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015084513

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19424772


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