Cloning and molecular characterization of a putative voltage-gated sodium channel gene in the crayfish View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-06

AUTHORS

Cagil Coskun, Nuhan Purali

ABSTRACT

Voltage-gated sodium channel genes and associated proteins have been cloned and studied in many mammalian and invertebrate species. However, there is no data available about the sodium channel gene(s) in the crayfish, although the animal has frequently been used as a model to investigate various aspects of neural cellular and circuit function. In the present work, by using RNA extracts from crayfish abdominal ganglia samples, the complete open reading frame of a putative sodium channel gene has firstly been cloned and molecular properties of the associated peptide have been analyzed. The open reading frame of the gene has a length of 5793 bp that encodes for the synthesis of a peptide, with 1930 amino acids, that is 82% similar to the α-peptide of a sodium channel in a neighboring species, Cancer borealis. The transmembrane topology analysis of the crayfish peptide indicated a pattern of four folding domains with several transmembrane segments, as observed in other known voltage-gated sodium channels. Upon analysis of the obtained sequence, functional regions of the putative sodium channel responsible for the selectivity filter, inactivation gate, voltage sensor, and phosphorylation have been predicted. The expression level of the putative sodium channel gene, as defined by a qPCR method, was measured and found to be the highest in nervous tissue. More... »

PAGES

2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10158-016-0185-4

DOI

http://dx.doi.org/10.1007/s10158-016-0185-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023146325

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27032955


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Astacoidea", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cloning, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Open Reading Frames", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Voltage-Gated Sodium Channels", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hacettepe University", 
          "id": "https://www.grid.ac/institutes/grid.14442.37", 
          "name": [
            "Department of Biophysics, Faculty of Medicine, Hacettepe University, 06100, Sihhiye, Ankara, Turkey"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Coskun", 
        "givenName": "Cagil", 
        "id": "sg:person.01237261265.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237261265.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hacettepe University", 
          "id": "https://www.grid.ac/institutes/grid.14442.37", 
          "name": [
            "Department of Biophysics, Faculty of Medicine, Hacettepe University, 06100, Sihhiye, Ankara, Turkey"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Purali", 
        "givenName": "Nuhan", 
        "id": "sg:person.0753655157.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753655157.03"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0022-2836(82)90515-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001452096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(96)66011-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001774806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkm256", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004179101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/neu.10214", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007257700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02577691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007514196", 
          "https://doi.org/10.1007/bf02577691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02577691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007514196", 
          "https://doi.org/10.1007/bf02577691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btm404", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007683223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1748-1716.1992.tb09394.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014493977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ps.392", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014689678"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fphar.2012.00124", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016425870"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biochi.2013.05.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019726603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m108258200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021349326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/expphysiol.2013.071969", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022688051"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10158-006-0036-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024685589", 
          "https://doi.org/10.1007/s10158-006-0036-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10158-006-0036-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024685589", 
          "https://doi.org/10.1007/s10158-006-0036-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1748-1716.1994.tb09672.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026537746"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(95)90279-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028817532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jmedent/45.6.1092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031295688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/pr.57.4.4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033404688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bcp.2008.09.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034784578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.1952.sp004764", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038260469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00424-011-1019-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039541277", 
          "https://doi.org/10.1007/s00424-011-1019-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02481713", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042586775", 
          "https://doi.org/10.1007/bf02481713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02481713", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042586775", 
          "https://doi.org/10.1007/bf02481713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/tjb-2016-0024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044353043"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0896-6273(04)00148-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045218977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.2000.3290", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047137116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0965-1748(00)00019-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050477153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cne.20590", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051978581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cne.20590", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051978581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m313100200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052243817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2583.2011.01079.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053137755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/pr.57.4.14", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053208465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-10-159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053736708", 
          "https://doi.org/10.1186/1471-2105-10-159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1065635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062445524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/stke.2532004re15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062692339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1603/0022-2585(2008)45[1092:bamaod]2.0.co;2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068117991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075125980", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jn.1998.80.4.2121", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083329732"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-06", 
    "datePublishedReg": "2016-06-01", 
    "description": "Voltage-gated sodium channel genes and associated proteins have been cloned and studied in many mammalian and invertebrate species. However, there is no data available about the sodium channel gene(s) in the crayfish, although the animal has frequently been used as a model to investigate various aspects of neural cellular and circuit function. In the present work, by using RNA extracts from crayfish abdominal ganglia samples, the complete open reading frame of a putative sodium channel gene has firstly been cloned and molecular properties of the associated peptide have been analyzed. The open reading frame of the gene has a length of 5793 bp that encodes for the synthesis of a peptide, with 1930 amino acids, that is 82% similar to the \u03b1-peptide of a sodium channel in a neighboring species, Cancer borealis. The transmembrane topology analysis of the crayfish peptide indicated a pattern of four folding domains with several transmembrane segments, as observed in other known voltage-gated sodium channels. Upon analysis of the obtained sequence, functional regions of the putative sodium channel responsible for the selectivity filter, inactivation gate, voltage sensor, and phosphorylation have been predicted. The expression level of the putative sodium channel gene, as defined by a qPCR method, was measured and found to be the highest in nervous tissue.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10158-016-0185-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1115073", 
        "issn": [
          "1354-2516", 
          "1439-1104"
        ], 
        "name": "Invertebrate Neuroscience", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "name": "Cloning and molecular characterization of a putative voltage-gated sodium channel gene in the crayfish", 
    "pagination": "2", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "6e4640380f0e44ee34344b8cc93c79b5c9bd6185ae212be009c76390b61fffec"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27032955"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9602489"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10158-016-0185-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1023146325"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10158-016-0185-4", 
      "https://app.dimensions.ai/details/publication/pub.1023146325"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:55", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8663_00000488.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s10158-016-0185-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10158-016-0185-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10158-016-0185-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10158-016-0185-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10158-016-0185-4'


 

This table displays all metadata directly associated to this object as RDF triples.

213 TRIPLES      21 PREDICATES      71 URIs      28 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10158-016-0185-4 schema:about N54a9520393be43ce89dbaed8816d3f02
2 N5675744f720c449c8b02e5e4b6db6403
3 N710b6482bfc442c2b3b409087f98afd9
4 N7833114c0c6c4253bdd46b31c5879e47
5 N79a30cc54bcb47099ad00feda1c1e511
6 Nba9237f34a234578a04e31478e4695ec
7 Nbf16aef99c5d48508e648192361f9245
8 anzsrc-for:06
9 anzsrc-for:0604
10 schema:author Nc96d3af28ef04a7ca2805a53e6580d51
11 schema:citation sg:pub.10.1007/bf02481713
12 sg:pub.10.1007/bf02577691
13 sg:pub.10.1007/s00424-011-1019-1
14 sg:pub.10.1007/s10158-006-0036-9
15 sg:pub.10.1186/1471-2105-10-159
16 https://app.dimensions.ai/details/publication/pub.1075125980
17 https://doi.org/10.1002/cne.20590
18 https://doi.org/10.1002/neu.10214
19 https://doi.org/10.1002/ps.392
20 https://doi.org/10.1006/bbrc.2000.3290
21 https://doi.org/10.1016/0022-2836(82)90515-0
22 https://doi.org/10.1016/0092-8674(95)90279-1
23 https://doi.org/10.1016/j.bcp.2008.09.008
24 https://doi.org/10.1016/j.biochi.2013.05.009
25 https://doi.org/10.1016/s0076-6879(96)66011-x
26 https://doi.org/10.1016/s0896-6273(04)00148-5
27 https://doi.org/10.1016/s0965-1748(00)00019-9
28 https://doi.org/10.1074/jbc.m108258200
29 https://doi.org/10.1074/jbc.m313100200
30 https://doi.org/10.1093/bioinformatics/btm404
31 https://doi.org/10.1093/jmedent/45.6.1092
32 https://doi.org/10.1093/nar/gkm256
33 https://doi.org/10.1111/j.1365-2583.2011.01079.x
34 https://doi.org/10.1111/j.1748-1716.1992.tb09394.x
35 https://doi.org/10.1111/j.1748-1716.1994.tb09672.x
36 https://doi.org/10.1113/expphysiol.2013.071969
37 https://doi.org/10.1113/jphysiol.1952.sp004764
38 https://doi.org/10.1124/pr.57.4.14
39 https://doi.org/10.1124/pr.57.4.4
40 https://doi.org/10.1126/science.1065635
41 https://doi.org/10.1126/stke.2532004re15
42 https://doi.org/10.1152/jn.1998.80.4.2121
43 https://doi.org/10.1515/tjb-2016-0024
44 https://doi.org/10.1603/0022-2585(2008)45[1092:bamaod]2.0.co;2
45 https://doi.org/10.3389/fphar.2012.00124
46 schema:datePublished 2016-06
47 schema:datePublishedReg 2016-06-01
48 schema:description Voltage-gated sodium channel genes and associated proteins have been cloned and studied in many mammalian and invertebrate species. However, there is no data available about the sodium channel gene(s) in the crayfish, although the animal has frequently been used as a model to investigate various aspects of neural cellular and circuit function. In the present work, by using RNA extracts from crayfish abdominal ganglia samples, the complete open reading frame of a putative sodium channel gene has firstly been cloned and molecular properties of the associated peptide have been analyzed. The open reading frame of the gene has a length of 5793 bp that encodes for the synthesis of a peptide, with 1930 amino acids, that is 82% similar to the α-peptide of a sodium channel in a neighboring species, Cancer borealis. The transmembrane topology analysis of the crayfish peptide indicated a pattern of four folding domains with several transmembrane segments, as observed in other known voltage-gated sodium channels. Upon analysis of the obtained sequence, functional regions of the putative sodium channel responsible for the selectivity filter, inactivation gate, voltage sensor, and phosphorylation have been predicted. The expression level of the putative sodium channel gene, as defined by a qPCR method, was measured and found to be the highest in nervous tissue.
49 schema:genre research_article
50 schema:inLanguage en
51 schema:isAccessibleForFree false
52 schema:isPartOf N6b042c057d0f42a7a54f6c4f1bb69065
53 Nec37ce5621b247ae89941f0cf25bf239
54 sg:journal.1115073
55 schema:name Cloning and molecular characterization of a putative voltage-gated sodium channel gene in the crayfish
56 schema:pagination 2
57 schema:productId N1f1b2117b74e4038916b2f37a8ab4f0f
58 N3ad497beda8841b0941bf892b6a7be6c
59 N92d9e6a5079a45e297bb721a978c7b9e
60 Nd6a162742a5e477e85ea35456bf1b1b3
61 Nfb23f8e5bde84e6ea92c69d14ed8ead5
62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023146325
63 https://doi.org/10.1007/s10158-016-0185-4
64 schema:sdDatePublished 2019-04-10T14:55
65 schema:sdLicense https://scigraph.springernature.com/explorer/license/
66 schema:sdPublisher N41dc61229d9a4150888a2ba151c45478
67 schema:url http://link.springer.com/10.1007/s10158-016-0185-4
68 sgo:license sg:explorer/license/
69 sgo:sdDataset articles
70 rdf:type schema:ScholarlyArticle
71 N1f1b2117b74e4038916b2f37a8ab4f0f schema:name doi
72 schema:value 10.1007/s10158-016-0185-4
73 rdf:type schema:PropertyValue
74 N23528101145f430897721d1a4a937233 rdf:first sg:person.0753655157.03
75 rdf:rest rdf:nil
76 N3ad497beda8841b0941bf892b6a7be6c schema:name nlm_unique_id
77 schema:value 9602489
78 rdf:type schema:PropertyValue
79 N41dc61229d9a4150888a2ba151c45478 schema:name Springer Nature - SN SciGraph project
80 rdf:type schema:Organization
81 N54a9520393be43ce89dbaed8816d3f02 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Amino Acid Sequence
83 rdf:type schema:DefinedTerm
84 N5675744f720c449c8b02e5e4b6db6403 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Polymerase Chain Reaction
86 rdf:type schema:DefinedTerm
87 N6b042c057d0f42a7a54f6c4f1bb69065 schema:issueNumber 2
88 rdf:type schema:PublicationIssue
89 N710b6482bfc442c2b3b409087f98afd9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Astacoidea
91 rdf:type schema:DefinedTerm
92 N7833114c0c6c4253bdd46b31c5879e47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Cloning, Molecular
94 rdf:type schema:DefinedTerm
95 N79a30cc54bcb47099ad00feda1c1e511 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Open Reading Frames
97 rdf:type schema:DefinedTerm
98 N92d9e6a5079a45e297bb721a978c7b9e schema:name readcube_id
99 schema:value 6e4640380f0e44ee34344b8cc93c79b5c9bd6185ae212be009c76390b61fffec
100 rdf:type schema:PropertyValue
101 Nba9237f34a234578a04e31478e4695ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Animals
103 rdf:type schema:DefinedTerm
104 Nbf16aef99c5d48508e648192361f9245 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Voltage-Gated Sodium Channels
106 rdf:type schema:DefinedTerm
107 Nc96d3af28ef04a7ca2805a53e6580d51 rdf:first sg:person.01237261265.01
108 rdf:rest N23528101145f430897721d1a4a937233
109 Nd6a162742a5e477e85ea35456bf1b1b3 schema:name pubmed_id
110 schema:value 27032955
111 rdf:type schema:PropertyValue
112 Nec37ce5621b247ae89941f0cf25bf239 schema:volumeNumber 16
113 rdf:type schema:PublicationVolume
114 Nfb23f8e5bde84e6ea92c69d14ed8ead5 schema:name dimensions_id
115 schema:value pub.1023146325
116 rdf:type schema:PropertyValue
117 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
118 schema:name Biological Sciences
119 rdf:type schema:DefinedTerm
120 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
121 schema:name Genetics
122 rdf:type schema:DefinedTerm
123 sg:journal.1115073 schema:issn 1354-2516
124 1439-1104
125 schema:name Invertebrate Neuroscience
126 rdf:type schema:Periodical
127 sg:person.01237261265.01 schema:affiliation https://www.grid.ac/institutes/grid.14442.37
128 schema:familyName Coskun
129 schema:givenName Cagil
130 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237261265.01
131 rdf:type schema:Person
132 sg:person.0753655157.03 schema:affiliation https://www.grid.ac/institutes/grid.14442.37
133 schema:familyName Purali
134 schema:givenName Nuhan
135 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753655157.03
136 rdf:type schema:Person
137 sg:pub.10.1007/bf02481713 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042586775
138 https://doi.org/10.1007/bf02481713
139 rdf:type schema:CreativeWork
140 sg:pub.10.1007/bf02577691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007514196
141 https://doi.org/10.1007/bf02577691
142 rdf:type schema:CreativeWork
143 sg:pub.10.1007/s00424-011-1019-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039541277
144 https://doi.org/10.1007/s00424-011-1019-1
145 rdf:type schema:CreativeWork
146 sg:pub.10.1007/s10158-006-0036-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024685589
147 https://doi.org/10.1007/s10158-006-0036-9
148 rdf:type schema:CreativeWork
149 sg:pub.10.1186/1471-2105-10-159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053736708
150 https://doi.org/10.1186/1471-2105-10-159
151 rdf:type schema:CreativeWork
152 https://app.dimensions.ai/details/publication/pub.1075125980 schema:CreativeWork
153 https://doi.org/10.1002/cne.20590 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051978581
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1002/neu.10214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007257700
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1002/ps.392 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014689678
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1006/bbrc.2000.3290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047137116
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/0022-2836(82)90515-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001452096
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/0092-8674(95)90279-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028817532
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/j.bcp.2008.09.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034784578
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/j.biochi.2013.05.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019726603
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/s0076-6879(96)66011-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001774806
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/s0896-6273(04)00148-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045218977
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/s0965-1748(00)00019-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050477153
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1074/jbc.m108258200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021349326
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1074/jbc.m313100200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052243817
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1093/bioinformatics/btm404 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007683223
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1093/jmedent/45.6.1092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031295688
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1093/nar/gkm256 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004179101
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1111/j.1365-2583.2011.01079.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053137755
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1111/j.1748-1716.1992.tb09394.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014493977
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1111/j.1748-1716.1994.tb09672.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026537746
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1113/expphysiol.2013.071969 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022688051
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1113/jphysiol.1952.sp004764 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038260469
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1124/pr.57.4.14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053208465
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1124/pr.57.4.4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033404688
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1126/science.1065635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062445524
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1126/stke.2532004re15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062692339
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1152/jn.1998.80.4.2121 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083329732
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1515/tjb-2016-0024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044353043
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1603/0022-2585(2008)45[1092:bamaod]2.0.co;2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068117991
208 rdf:type schema:CreativeWork
209 https://doi.org/10.3389/fphar.2012.00124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016425870
210 rdf:type schema:CreativeWork
211 https://www.grid.ac/institutes/grid.14442.37 schema:alternateName Hacettepe University
212 schema:name Department of Biophysics, Faculty of Medicine, Hacettepe University, 06100, Sihhiye, Ankara, Turkey
213 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...