Long-term social outcome after pediatric kidney transplantation: a single-center experience View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2022-01-06

AUTHORS

Yuko Hamasaki, Junya Hashimoto, Yujiro Aoki, Mai Kubota, Masaki Muramatsu, Takeshi Kawamura, Seiichiro Shishido, Ken Sakai

ABSTRACT

BackgroundPatient and graft survival rates after pediatric kidney transplantation have improved recently. Therefore, the quality of life or social outcome after kidney transplantation has become important for patients and their families.MethodsPatients who underwent kidney transplantation at < 18 years old and were observed for > 10 years were included in this study. The median age at first kidney transplantation was 9.2 (interquartile range [IQR] = 5.6–13.0) years; there were 56 males and 50 females. The median age at last follow-up was 29.9 (IQR = 22.2–36.0) years. We evaluated the patients’ renal function, growth, professional status, and marital status at the last follow-up.ResultsThe percentage of functioning grafts at the last follow-up was 81.1%; 73 patients (68.9%) had a first graft. The mean estimated GFR was 51.0 ± 20.5 mL/min/1.73 m2. Twenty patients received dialysis for graft failure. The mean final heights of the males and females were 158.1 ± 9.2 cm (− 2.2 standard deviations) and 149.1 ± 6.4 cm (− 1.7 standard deviations), respectively. Excluding 23 students, 63 patients (75.9%) were employed. Office worker was the most common profession. Twelve patients (14.5%) were unemployed. Of patients > 20 years old, 14 (16.7%), three males and 11 females, were married. Five females had one child each.ConclusionsThe graft survival rate was favorable. The final height was short, particularly in male. The rate of employment was relatively high. The rate of marriage and having children were still low. Improving the social outcome is an important problem after pediatric kidney transplantation. More... »

PAGES

368-375

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10157-021-02158-w

DOI

http://dx.doi.org/10.1007/s10157-021-02158-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1144440159

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34988725


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25 schema:description BackgroundPatient and graft survival rates after pediatric kidney transplantation have improved recently. Therefore, the quality of life or social outcome after kidney transplantation has become important for patients and their families.MethodsPatients who underwent kidney transplantation at < 18 years old and were observed for > 10 years were included in this study. The median age at first kidney transplantation was 9.2 (interquartile range [IQR] = 5.6–13.0) years; there were 56 males and 50 females. The median age at last follow-up was 29.9 (IQR = 22.2–36.0) years. We evaluated the patients’ renal function, growth, professional status, and marital status at the last follow-up.ResultsThe percentage of functioning grafts at the last follow-up was 81.1%; 73 patients (68.9%) had a first graft. The mean estimated GFR was 51.0 ± 20.5 mL/min/1.73 m2. Twenty patients received dialysis for graft failure. The mean final heights of the males and females were 158.1 ± 9.2 cm (− 2.2 standard deviations) and 149.1 ± 6.4 cm (− 1.7 standard deviations), respectively. Excluding 23 students, 63 patients (75.9%) were employed. Office worker was the most common profession. Twelve patients (14.5%) were unemployed. Of patients > 20 years old, 14 (16.7%), three males and 11 females, were married. Five females had one child each.ConclusionsThe graft survival rate was favorable. The final height was short, particularly in male. The rate of employment was relatively high. The rate of marriage and having children were still low. Improving the social outcome is an important problem after pediatric kidney transplantation.
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