Clinical guides for atypical hemolytic uremic syndrome in Japan View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-07-15

AUTHORS

Hideki Kato, Masaomi Nangaku, Hiroshi Hataya, Toshihiro Sawai, Akira Ashida, Rika Fujimaru, Yoshihiko Hidaka, Shinya Kaname, Shoichi Maruyama, Takashi Yasuda, Yoko Yoshida, Shuichi Ito, Motoshi Hattori, Yoshitaka Miyakawa, Yoshihiro Fujimura, Hirokazu Okada, Shoji Kagami, The Joint Committee for the Revision of Clinical Guides of Atypical Hemolytic Uremic Syndrome in Japan

ABSTRACT

Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. In 2013, we developed diagnostic criteria to enable early diagnosis and timely initiation of appropriate treatment for aHUS. Recent clinical and molecular findings have resulted in several proposed classifications and definitions of thrombotic microangiopathy and aHUS. Based on recent advances in this field and the emerging international consensus to exclude secondary TMAs from the definition of aHUS, we have redefined aHUS and proposed diagnostic algorithms, differential diagnosis, and therapeutic strategies for aHUS. More... »

PAGES

536-543

Journal

TITLE

Clinical and Experimental Nephrology

ISSUE

4

VOLUME

20

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10157-016-1276-6

DOI

http://dx.doi.org/10.1007/s10157-016-1276-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023786470

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27422619


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31 anemia
32 appropriate treatment
33 atypical hemolytic uremic syndrome
34 classification
35 clinical guide
36 consensus
37 criteria
38 definition
39 diagnosis
40 diagnostic algorithm
41 diagnostic criteria
42 differential diagnosis
43 disease
44 early diagnosis
45 field
46 findings
47 guide
48 hemolytic anemia
49 hemolytic uremic syndrome
50 initiation
51 injury
52 international consensus
53 kidney injury
54 microangiopathic hemolytic anemia
55 microangiopathy
56 molecular findings
57 rare disease
58 recent advances
59 secondary TMA
60 strategies
61 syndrome
62 therapeutic strategies
63 thrombocytopenia
64 thrombotic microangiopathy
65 timely initiation
66 treatment
67 triad
68 uremic syndrome
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