Expression of a novel endothelial marker, C-type lectin 14A, in epithelial ovarian cancer and its prognostic significance View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-02

AUTHORS

S. Krishna Priya, Kishore Kumar, K. R. Hiran, M. R. Bindhu, Rohit. P. Nagare, D. K. Vijaykumar, T. S. Ganesan

ABSTRACT

OBJECTIVE: The purpose of this study was to evaluate microvessel density (MVD) as assessed by C-type lectin 14A (CLEC14A), which is a new marker for endothelial cells, and compare its expression to CD31 and CD105 in epithelial ovarian cancer (EOC). METHODS: MVD was evaluated in tumors (n = 50) from patients with EOC who underwent primary surgery and in patients with EOC who received preoperative chemotherapy (n = 49) using immunohistochemistry with antibodies to CLEC14A, CD31 and CD105. The median duration of follow-up was 24.5 months (range 1-101 months). The effect of prognostic factors on event-free survival (EFS) and overall survival (OS) was assessed using the Cox regression model. RESULTS: The amount of residual disease was found to be an independent prognostic factor in multivariate analysis with respect to EFS (P = 0.009) and OS (P < 0.001). The mean MVD of CLEC14A (MVD = 6), in tumors from patients who underwent primary surgery, was significantly lower than that of CD31 (MVD = 25, P < 0.0001) and CD105 (MVD = 11, P = 0.018). However, there was no significant correlation between MVD as detected by these markers and clinical outcome. There was no expression of CLEC14A in tumors from patients who received preoperative chemotherapy and the MVD of CD31 and CD105 was significantly reduced (P = 0.001 and 0.006, respectively) in this set of patients. CONCLUSION: This study demonstrates MVD as detected by CLEC14A in EOC. Treatment with chemotherapy reduces tumor blood vessels significantly. We suggest that CLEC14A may be a more specific endothelial marker to assess tumor angiogenesis. More... »

PAGES

107-117

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10147-016-1033-6

DOI

http://dx.doi.org/10.1007/s10147-016-1033-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024965768

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27567920


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Ovarian Epithelial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Adhesion Molecules", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chemotherapy, Adjuvant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease-Free Survival", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endoglin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lectins, C-Type", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microvessels", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoadjuvant Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm, Residual", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms, Glandular and Epithelial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neovascularization, Pathologic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ovarian Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Platelet Endothelial Cell Adhesion Molecule-1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.418600.b", 
          "name": [
            "Laboratory for Cancer Biology, Medical Oncology and Clinical Research, Cancer Institute (WIA), 38, Sardar Patel Road, Guindy, 600036, Chennai, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Krishna Priya", 
        "givenName": "S.", 
        "id": "sg:person.07771427211.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07771427211.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Command Hospital", 
          "id": "https://www.grid.ac/institutes/grid.414653.1", 
          "name": [
            "Medical Oncology, Command Hospital (CC), Lucknow Cantt., 226002, Lucknow, UP, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumar", 
        "givenName": "Kishore", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Amrita Institute of Medical Sciences and Research Centre", 
          "id": "https://www.grid.ac/institutes/grid.427788.6", 
          "name": [
            "Department of Histopathology, Amrita Institute of Medical Sciences and Research Centre, 682041, Cochin, Kerala, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hiran", 
        "givenName": "K. R.", 
        "id": "sg:person.01054370124.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054370124.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Amrita Institute of Medical Sciences and Research Centre", 
          "id": "https://www.grid.ac/institutes/grid.427788.6", 
          "name": [
            "Department of Histopathology, Amrita Institute of Medical Sciences and Research Centre, 682041, Cochin, Kerala, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bindhu", 
        "givenName": "M. R.", 
        "id": "sg:person.0745260342.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745260342.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.418600.b", 
          "name": [
            "Laboratory for Cancer Biology, Medical Oncology and Clinical Research, Cancer Institute (WIA), 38, Sardar Patel Road, Guindy, 600036, Chennai, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagare", 
        "givenName": "Rohit. P.", 
        "id": "sg:person.015677120011.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015677120011.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Amrita Institute of Medical Sciences and Research Centre", 
          "id": "https://www.grid.ac/institutes/grid.427788.6", 
          "name": [
            "Department of Surgical Oncology, Amrita Institute of Medical Sciences and Research Centre, 682041, Cochin, Kerala, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vijaykumar", 
        "givenName": "D. K.", 
        "id": "sg:person.0577433674.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577433674.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.418600.b", 
          "name": [
            "Laboratory for Cancer Biology, Medical Oncology and Clinical Research, Cancer Institute (WIA), 38, Sardar Patel Road, Guindy, 600036, Chennai, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ganesan", 
        "givenName": "T. S.", 
        "id": "sg:person.01354150255.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354150255.82"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1309/1kf54l6rb625556w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000084035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0463.2004.apm11207-0803.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001936516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-11-2188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003033217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-14-1143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004150869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13277-011-0157-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004601551", 
          "https://doi.org/10.1007/s13277-011-0157-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.284.5419.1534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006132706"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/mcp.m113.031344", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008617664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2015.34", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010777828", 
          "https://doi.org/10.1038/onc.2015.34"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6603491", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011822835", 
          "https://doi.org/10.1038/sj.bjc.6603491"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6603491", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011822835", 
          "https://doi.org/10.1038/sj.bjc.6603491"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/2159-8290.cd-12-0095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011831914"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1309/x6nxye57dlue2nq8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012318624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/bju.12986", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012444850"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(92)93150-l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012584461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(92)93150-l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012584461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006250-200004000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015005866"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006250-200004000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015005866"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ygyno.2008.11.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019016626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021001335", 
          "https://doi.org/10.1038/modpathol.3800034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021001335", 
          "https://doi.org/10.1038/modpathol.3800034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-12-0098", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021530646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-12-0098", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021530646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.30067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024764524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst20110746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026108282"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst20110746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026108282"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2010.11.075", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027135959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2013.156", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027699651", 
          "https://doi.org/10.1038/onc.2013.156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6603144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029222554", 
          "https://doi.org/10.1038/sj.bjc.6603144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6603144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029222554", 
          "https://doi.org/10.1038/sj.bjc.6603144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00428-013-1463-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029329585", 
          "https://doi.org/10.1007/s00428-013-1463-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00428-013-1463-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029329585", 
          "https://doi.org/10.1007/s00428-013-1463-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jcp.43.9.752", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030546454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm197111182852108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031952402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1998.367", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033661626", 
          "https://doi.org/10.1038/bjc.1998.367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1998.367", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033661626", 
          "https://doi.org/10.1038/bjc.1998.367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/scisignal.2004088", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033807182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1104390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035779003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1104390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035779003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1525-1438.2006.00658.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036092557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2011.233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038146202", 
          "https://doi.org/10.1038/onc.2011.233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-07-0237", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038240570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.10462", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038650754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.83.20.7898", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040042202"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm197108122850711", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042994614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7314/apjcp.2015.16.3.869", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044744261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1103799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052109861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1103799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052109861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.11699", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053394597"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01621459.1958.10501452", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058299418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/etm.2012.594", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071503328"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074272977", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078420587", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078832089", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082392557", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082405434", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-02", 
    "datePublishedReg": "2017-02-01", 
    "description": "OBJECTIVE: The purpose of this study was to evaluate microvessel density (MVD) as assessed by C-type lectin 14A (CLEC14A), which is a new marker for endothelial cells, and compare its expression to CD31 and CD105 in epithelial ovarian cancer (EOC).\nMETHODS: MVD was evaluated in tumors (n\u00a0=\u00a050) from patients with EOC who underwent primary surgery and in patients with EOC who received preoperative chemotherapy (n\u00a0=\u00a049) using immunohistochemistry with antibodies to CLEC14A, CD31 and CD105. The median duration of follow-up was 24.5\u00a0months (range 1-101\u00a0months). The effect of prognostic factors on event-free survival (EFS) and overall survival (OS) was assessed using the Cox regression model.\nRESULTS: The amount of residual disease was found to be an independent prognostic factor in multivariate analysis with respect to EFS (P\u00a0=\u00a00.009) and OS (P\u00a0<\u00a00.001). The mean MVD of CLEC14A (MVD\u00a0=\u00a06), in tumors from patients who underwent primary surgery, was significantly lower than that of CD31 (MVD\u00a0=\u00a025, P\u00a0<\u00a00.0001) and CD105 (MVD\u00a0=\u00a011, P\u00a0=\u00a00.018). However, there was no significant correlation between MVD as detected by these markers and clinical outcome. There was no expression of CLEC14A in tumors from patients who received preoperative chemotherapy and the MVD of CD31 and CD105 was significantly reduced (P\u00a0=\u00a00.001 and 0.006, respectively) in this set of patients.\nCONCLUSION: This study demonstrates MVD as detected by CLEC14A in EOC. Treatment with chemotherapy reduces tumor blood vessels significantly. We suggest that CLEC14A may be a more specific endothelial marker to assess tumor angiogenesis.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10147-016-1033-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1312225", 
        "issn": [
          "1341-9625", 
          "1437-7772"
        ], 
        "name": "International Journal of Clinical Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "22"
      }
    ], 
    "name": "Expression of a novel endothelial marker, C-type lectin 14A, in epithelial ovarian cancer and its prognostic significance", 
    "pagination": "107-117", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "76ef5fec211d61b4882294bfbc8cec9ee797c1824173bf28f903f9e0b8d71564"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27567920"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9616295"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10147-016-1033-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1024965768"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10147-016-1033-6", 
      "https://app.dimensions.ai/details/publication/pub.1024965768"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87112_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10147-016-1033-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10147-016-1033-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10147-016-1033-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10147-016-1033-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10147-016-1033-6'


 

This table displays all metadata directly associated to this object as RDF triples.

349 TRIPLES      21 PREDICATES      97 URIs      45 LITERALS      33 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10147-016-1033-6 schema:about N0f4fcba820ec40399a903ae5f13001aa
2 N253159c988db4149a88419f8d70bd6e1
3 N267cf2d2ad1c442896eb1f939a3d2491
4 N3ac152d9014c4172bc01894d42e7e1cc
5 N3c9f15c49b354d4db01ec0ab3da63c79
6 N3e20d15532154cbcaf7ab12b3c9a0b13
7 N42b8d63b549c43e1abdd6f356b946694
8 N42cae99eafdf4ab7a2f75b84f5d0b2aa
9 N487bdb266a0542f399e7d8352c9d7f27
10 N48eee0b2e89e4ea79999e960d482ef7f
11 N59d722cb5851450485de0c63b3d4b577
12 N5cda023ed0db4a4989dcd8ece7026100
13 N69fdc24169b84de28022360a11188653
14 N6b18d0ca01474c348265c67ea2e7c594
15 N7c4dd3e90f49422191cd973b61f01f7c
16 N7d131588c347482b80ef793e4f32f20b
17 N814e6927846f4396b8de92ea3d920a68
18 N869c19db384f469db54782195ad90c8c
19 N8d46dc5b3b5e41bda5187f89424ebf43
20 Na13fd30119e64f009b00bbce4e5a41e1
21 Nac7d5943654d45ddb6b6cce904e62bee
22 Nb8602dfcc7954b7fb17ef4e6b0f439aa
23 Nd75690181b7041b7aad26d0e719da884
24 Neb4684703a764e71942af6ee8dcfbf32
25 anzsrc-for:11
26 anzsrc-for:1112
27 schema:author N4f86a7d1196244c0b51e894e24799abd
28 schema:citation sg:pub.10.1007/s00428-013-1463-8
29 sg:pub.10.1007/s13277-011-0157-6
30 sg:pub.10.1038/bjc.1998.367
31 sg:pub.10.1038/modpathol.3800034
32 sg:pub.10.1038/onc.2011.233
33 sg:pub.10.1038/onc.2013.156
34 sg:pub.10.1038/onc.2015.34
35 sg:pub.10.1038/sj.bjc.6603144
36 sg:pub.10.1038/sj.bjc.6603491
37 https://app.dimensions.ai/details/publication/pub.1074272977
38 https://app.dimensions.ai/details/publication/pub.1078420587
39 https://app.dimensions.ai/details/publication/pub.1078832089
40 https://app.dimensions.ai/details/publication/pub.1082392557
41 https://app.dimensions.ai/details/publication/pub.1082405434
42 https://doi.org/10.1002/ijc.10462
43 https://doi.org/10.1002/ijc.11699
44 https://doi.org/10.1002/ijc.30067
45 https://doi.org/10.1016/0140-6736(92)93150-l
46 https://doi.org/10.1016/j.bbrc.2010.11.075
47 https://doi.org/10.1016/j.ygyno.2008.11.030
48 https://doi.org/10.1042/bst20110746
49 https://doi.org/10.1056/nejm197108122850711
50 https://doi.org/10.1056/nejm197111182852108
51 https://doi.org/10.1056/nejmoa1103799
52 https://doi.org/10.1056/nejmoa1104390
53 https://doi.org/10.1073/pnas.83.20.7898
54 https://doi.org/10.1074/mcp.m113.031344
55 https://doi.org/10.1080/01621459.1958.10501452
56 https://doi.org/10.1097/00006250-200004000-00013
57 https://doi.org/10.1111/bju.12986
58 https://doi.org/10.1111/j.1525-1438.2006.00658.x
59 https://doi.org/10.1111/j.1600-0463.2004.apm11207-0803.x
60 https://doi.org/10.1126/science.284.5419.1534
61 https://doi.org/10.1126/scisignal.2004088
62 https://doi.org/10.1136/jcp.43.9.752
63 https://doi.org/10.1158/1078-0432.ccr-11-2188
64 https://doi.org/10.1158/1078-0432.ccr-12-0098
65 https://doi.org/10.1158/1078-0432.ccr-14-1143
66 https://doi.org/10.1158/1535-7163.mct-07-0237
67 https://doi.org/10.1158/2159-8290.cd-12-0095
68 https://doi.org/10.1309/1kf54l6rb625556w
69 https://doi.org/10.1309/x6nxye57dlue2nq8
70 https://doi.org/10.3892/etm.2012.594
71 https://doi.org/10.7314/apjcp.2015.16.3.869
72 schema:datePublished 2017-02
73 schema:datePublishedReg 2017-02-01
74 schema:description OBJECTIVE: The purpose of this study was to evaluate microvessel density (MVD) as assessed by C-type lectin 14A (CLEC14A), which is a new marker for endothelial cells, and compare its expression to CD31 and CD105 in epithelial ovarian cancer (EOC). METHODS: MVD was evaluated in tumors (n = 50) from patients with EOC who underwent primary surgery and in patients with EOC who received preoperative chemotherapy (n = 49) using immunohistochemistry with antibodies to CLEC14A, CD31 and CD105. The median duration of follow-up was 24.5 months (range 1-101 months). The effect of prognostic factors on event-free survival (EFS) and overall survival (OS) was assessed using the Cox regression model. RESULTS: The amount of residual disease was found to be an independent prognostic factor in multivariate analysis with respect to EFS (P = 0.009) and OS (P < 0.001). The mean MVD of CLEC14A (MVD = 6), in tumors from patients who underwent primary surgery, was significantly lower than that of CD31 (MVD = 25, P < 0.0001) and CD105 (MVD = 11, P = 0.018). However, there was no significant correlation between MVD as detected by these markers and clinical outcome. There was no expression of CLEC14A in tumors from patients who received preoperative chemotherapy and the MVD of CD31 and CD105 was significantly reduced (P = 0.001 and 0.006, respectively) in this set of patients. CONCLUSION: This study demonstrates MVD as detected by CLEC14A in EOC. Treatment with chemotherapy reduces tumor blood vessels significantly. We suggest that CLEC14A may be a more specific endothelial marker to assess tumor angiogenesis.
75 schema:genre research_article
76 schema:inLanguage en
77 schema:isAccessibleForFree false
78 schema:isPartOf Na3450465f9ba4d499f3ddeb836628bb6
79 Nf98b846c6d4742b5992665e588b9c174
80 sg:journal.1312225
81 schema:name Expression of a novel endothelial marker, C-type lectin 14A, in epithelial ovarian cancer and its prognostic significance
82 schema:pagination 107-117
83 schema:productId N98701f181f54415ba8b7a72a3aa52bbe
84 N9b43ec822a644cc38ee272800a93b2d8
85 Na2976522408e405389327fb78dc5217c
86 Nc394bf3796a54202b0131472c4ab04ab
87 Ncd2c206f5a23470cbd001882cff1a927
88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024965768
89 https://doi.org/10.1007/s10147-016-1033-6
90 schema:sdDatePublished 2019-04-11T12:26
91 schema:sdLicense https://scigraph.springernature.com/explorer/license/
92 schema:sdPublisher Nd0955cfb61e144f1a5295b043016359c
93 schema:url https://link.springer.com/10.1007%2Fs10147-016-1033-6
94 sgo:license sg:explorer/license/
95 sgo:sdDataset articles
96 rdf:type schema:ScholarlyArticle
97 N0f4fcba820ec40399a903ae5f13001aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Disease-Free Survival
99 rdf:type schema:DefinedTerm
100 N253159c988db4149a88419f8d70bd6e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Neoplasm, Residual
102 rdf:type schema:DefinedTerm
103 N267cf2d2ad1c442896eb1f939a3d2491 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Biomarkers, Tumor
105 rdf:type schema:DefinedTerm
106 N269019cf1aa941079eb6206edc37cb96 rdf:first sg:person.01054370124.03
107 rdf:rest N459d73c55df440fb89d6aff0219660d5
108 N3ac152d9014c4172bc01894d42e7e1cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Immunohistochemistry
110 rdf:type schema:DefinedTerm
111 N3c9f15c49b354d4db01ec0ab3da63c79 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Aged
113 rdf:type schema:DefinedTerm
114 N3e20d15532154cbcaf7ab12b3c9a0b13 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Follow-Up Studies
116 rdf:type schema:DefinedTerm
117 N42b8d63b549c43e1abdd6f356b946694 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Aged, 80 and over
119 rdf:type schema:DefinedTerm
120 N42cae99eafdf4ab7a2f75b84f5d0b2aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Neoadjuvant Therapy
122 rdf:type schema:DefinedTerm
123 N459d73c55df440fb89d6aff0219660d5 rdf:first sg:person.0745260342.67
124 rdf:rest Ncfbde93b3b8e456f8282924f1ac7e063
125 N487bdb266a0542f399e7d8352c9d7f27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Adult
127 rdf:type schema:DefinedTerm
128 N48eee0b2e89e4ea79999e960d482ef7f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Neovascularization, Pathologic
130 rdf:type schema:DefinedTerm
131 N4f86a7d1196244c0b51e894e24799abd rdf:first sg:person.07771427211.35
132 rdf:rest Nc747fafd40694c0fb137c9a3e817aaf8
133 N59d722cb5851450485de0c63b3d4b577 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Chemotherapy, Adjuvant
135 rdf:type schema:DefinedTerm
136 N5cda023ed0db4a4989dcd8ece7026100 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Female
138 rdf:type schema:DefinedTerm
139 N69fdc24169b84de28022360a11188653 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Humans
141 rdf:type schema:DefinedTerm
142 N6b18d0ca01474c348265c67ea2e7c594 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Ovarian Neoplasms
144 rdf:type schema:DefinedTerm
145 N7c4dd3e90f49422191cd973b61f01f7c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Neoplasms, Glandular and Epithelial
147 rdf:type schema:DefinedTerm
148 N7d131588c347482b80ef793e4f32f20b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Platelet Endothelial Cell Adhesion Molecule-1
150 rdf:type schema:DefinedTerm
151 N814e6927846f4396b8de92ea3d920a68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Endoglin
153 rdf:type schema:DefinedTerm
154 N869c19db384f469db54782195ad90c8c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Lectins, C-Type
156 rdf:type schema:DefinedTerm
157 N8d46dc5b3b5e41bda5187f89424ebf43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Carcinoma, Ovarian Epithelial
159 rdf:type schema:DefinedTerm
160 N98701f181f54415ba8b7a72a3aa52bbe schema:name dimensions_id
161 schema:value pub.1024965768
162 rdf:type schema:PropertyValue
163 N9b43ec822a644cc38ee272800a93b2d8 schema:name doi
164 schema:value 10.1007/s10147-016-1033-6
165 rdf:type schema:PropertyValue
166 N9fd2d5645fcc45849758f199ad5959ce rdf:first sg:person.0577433674.57
167 rdf:rest Nf95e1b3eaaa04b1da45aca1a9677127a
168 Na13fd30119e64f009b00bbce4e5a41e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Cell Adhesion Molecules
170 rdf:type schema:DefinedTerm
171 Na2976522408e405389327fb78dc5217c schema:name nlm_unique_id
172 schema:value 9616295
173 rdf:type schema:PropertyValue
174 Na3450465f9ba4d499f3ddeb836628bb6 schema:volumeNumber 22
175 rdf:type schema:PublicationVolume
176 Nac7d5943654d45ddb6b6cce904e62bee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Microvessels
178 rdf:type schema:DefinedTerm
179 Nb8602dfcc7954b7fb17ef4e6b0f439aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Survival Rate
181 rdf:type schema:DefinedTerm
182 Nc394bf3796a54202b0131472c4ab04ab schema:name pubmed_id
183 schema:value 27567920
184 rdf:type schema:PropertyValue
185 Nc747fafd40694c0fb137c9a3e817aaf8 rdf:first Ne9862a63a54f401db95fa14e31ac5aeb
186 rdf:rest N269019cf1aa941079eb6206edc37cb96
187 Ncd2c206f5a23470cbd001882cff1a927 schema:name readcube_id
188 schema:value 76ef5fec211d61b4882294bfbc8cec9ee797c1824173bf28f903f9e0b8d71564
189 rdf:type schema:PropertyValue
190 Ncfbde93b3b8e456f8282924f1ac7e063 rdf:first sg:person.015677120011.26
191 rdf:rest N9fd2d5645fcc45849758f199ad5959ce
192 Nd0955cfb61e144f1a5295b043016359c schema:name Springer Nature - SN SciGraph project
193 rdf:type schema:Organization
194 Nd75690181b7041b7aad26d0e719da884 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Middle Aged
196 rdf:type schema:DefinedTerm
197 Ne9862a63a54f401db95fa14e31ac5aeb schema:affiliation https://www.grid.ac/institutes/grid.414653.1
198 schema:familyName Kumar
199 schema:givenName Kishore
200 rdf:type schema:Person
201 Neb4684703a764e71942af6ee8dcfbf32 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Young Adult
203 rdf:type schema:DefinedTerm
204 Nf95e1b3eaaa04b1da45aca1a9677127a rdf:first sg:person.01354150255.82
205 rdf:rest rdf:nil
206 Nf98b846c6d4742b5992665e588b9c174 schema:issueNumber 1
207 rdf:type schema:PublicationIssue
208 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
209 schema:name Medical and Health Sciences
210 rdf:type schema:DefinedTerm
211 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
212 schema:name Oncology and Carcinogenesis
213 rdf:type schema:DefinedTerm
214 sg:journal.1312225 schema:issn 1341-9625
215 1437-7772
216 schema:name International Journal of Clinical Oncology
217 rdf:type schema:Periodical
218 sg:person.01054370124.03 schema:affiliation https://www.grid.ac/institutes/grid.427788.6
219 schema:familyName Hiran
220 schema:givenName K. R.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054370124.03
222 rdf:type schema:Person
223 sg:person.01354150255.82 schema:affiliation https://www.grid.ac/institutes/grid.418600.b
224 schema:familyName Ganesan
225 schema:givenName T. S.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354150255.82
227 rdf:type schema:Person
228 sg:person.015677120011.26 schema:affiliation https://www.grid.ac/institutes/grid.418600.b
229 schema:familyName Nagare
230 schema:givenName Rohit. P.
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015677120011.26
232 rdf:type schema:Person
233 sg:person.0577433674.57 schema:affiliation https://www.grid.ac/institutes/grid.427788.6
234 schema:familyName Vijaykumar
235 schema:givenName D. K.
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577433674.57
237 rdf:type schema:Person
238 sg:person.0745260342.67 schema:affiliation https://www.grid.ac/institutes/grid.427788.6
239 schema:familyName Bindhu
240 schema:givenName M. R.
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745260342.67
242 rdf:type schema:Person
243 sg:person.07771427211.35 schema:affiliation https://www.grid.ac/institutes/grid.418600.b
244 schema:familyName Krishna Priya
245 schema:givenName S.
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07771427211.35
247 rdf:type schema:Person
248 sg:pub.10.1007/s00428-013-1463-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029329585
249 https://doi.org/10.1007/s00428-013-1463-8
250 rdf:type schema:CreativeWork
251 sg:pub.10.1007/s13277-011-0157-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004601551
252 https://doi.org/10.1007/s13277-011-0157-6
253 rdf:type schema:CreativeWork
254 sg:pub.10.1038/bjc.1998.367 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033661626
255 https://doi.org/10.1038/bjc.1998.367
256 rdf:type schema:CreativeWork
257 sg:pub.10.1038/modpathol.3800034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021001335
258 https://doi.org/10.1038/modpathol.3800034
259 rdf:type schema:CreativeWork
260 sg:pub.10.1038/onc.2011.233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038146202
261 https://doi.org/10.1038/onc.2011.233
262 rdf:type schema:CreativeWork
263 sg:pub.10.1038/onc.2013.156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027699651
264 https://doi.org/10.1038/onc.2013.156
265 rdf:type schema:CreativeWork
266 sg:pub.10.1038/onc.2015.34 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010777828
267 https://doi.org/10.1038/onc.2015.34
268 rdf:type schema:CreativeWork
269 sg:pub.10.1038/sj.bjc.6603144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029222554
270 https://doi.org/10.1038/sj.bjc.6603144
271 rdf:type schema:CreativeWork
272 sg:pub.10.1038/sj.bjc.6603491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011822835
273 https://doi.org/10.1038/sj.bjc.6603491
274 rdf:type schema:CreativeWork
275 https://app.dimensions.ai/details/publication/pub.1074272977 schema:CreativeWork
276 https://app.dimensions.ai/details/publication/pub.1078420587 schema:CreativeWork
277 https://app.dimensions.ai/details/publication/pub.1078832089 schema:CreativeWork
278 https://app.dimensions.ai/details/publication/pub.1082392557 schema:CreativeWork
279 https://app.dimensions.ai/details/publication/pub.1082405434 schema:CreativeWork
280 https://doi.org/10.1002/ijc.10462 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038650754
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1002/ijc.11699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053394597
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1002/ijc.30067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024764524
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/0140-6736(92)93150-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1012584461
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/j.bbrc.2010.11.075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027135959
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1016/j.ygyno.2008.11.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019016626
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1042/bst20110746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026108282
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1056/nejm197108122850711 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042994614
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1056/nejm197111182852108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031952402
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1056/nejmoa1103799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052109861
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1056/nejmoa1104390 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035779003
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1073/pnas.83.20.7898 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040042202
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1074/mcp.m113.031344 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008617664
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1080/01621459.1958.10501452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058299418
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1097/00006250-200004000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015005866
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1111/bju.12986 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012444850
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1111/j.1525-1438.2006.00658.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036092557
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1111/j.1600-0463.2004.apm11207-0803.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001936516
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1126/science.284.5419.1534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006132706
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1126/scisignal.2004088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033807182
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1136/jcp.43.9.752 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030546454
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1158/1078-0432.ccr-11-2188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003033217
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1158/1078-0432.ccr-12-0098 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021530646
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1158/1078-0432.ccr-14-1143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004150869
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1158/1535-7163.mct-07-0237 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038240570
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1158/2159-8290.cd-12-0095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011831914
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1309/1kf54l6rb625556w schema:sameAs https://app.dimensions.ai/details/publication/pub.1000084035
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1309/x6nxye57dlue2nq8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012318624
335 rdf:type schema:CreativeWork
336 https://doi.org/10.3892/etm.2012.594 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071503328
337 rdf:type schema:CreativeWork
338 https://doi.org/10.7314/apjcp.2015.16.3.869 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044744261
339 rdf:type schema:CreativeWork
340 https://www.grid.ac/institutes/grid.414653.1 schema:alternateName Command Hospital
341 schema:name Medical Oncology, Command Hospital (CC), Lucknow Cantt., 226002, Lucknow, UP, India
342 rdf:type schema:Organization
343 https://www.grid.ac/institutes/grid.418600.b schema:alternateName Cancer Institute
344 schema:name Laboratory for Cancer Biology, Medical Oncology and Clinical Research, Cancer Institute (WIA), 38, Sardar Patel Road, Guindy, 600036, Chennai, Tamil Nadu, India
345 rdf:type schema:Organization
346 https://www.grid.ac/institutes/grid.427788.6 schema:alternateName Amrita Institute of Medical Sciences and Research Centre
347 schema:name Department of Histopathology, Amrita Institute of Medical Sciences and Research Centre, 682041, Cochin, Kerala, India
348 Department of Surgical Oncology, Amrita Institute of Medical Sciences and Research Centre, 682041, Cochin, Kerala, India
349 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...